Estudo randomizado | Entre pacientes com câncer colorretal metastático, os randomizados para tratamento sistêmico isolado tiveram menor mortalidade em 60 dias do que aqueles randomizados para ressecção de tumor primário seguida de tratamento sistêmico.

Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment: The CAIRO4 Phase 3 Randomized Clinical Trial – JAMA Surgery (gratuito por tempo limitado)

Editorial: Primary Tumor Resection and Patients With Asymptomatic Colorectal Cancer and Nonresectable Metastases: Results of Recent Randomized Trials – JAMA Surgery (gratuito por tempo limitado)

Comentário: Systemic Therapy Alone Bests Surgical Tx for Metastatic CRC – BreakingMed

Comentário no Twitter

Early mortality in patients with colorectal cancer and unresectable metastases randomized to primary tumor resection followed by systemic treatment is considerably higher than early mortality in patients randomized to systemic treatment only https://t.co/SyfYjmDU7i @DaveKruijssen

— JAMA Surgery (@JAMASurgery) October 11, 2021