Estudo randomizado | Em mulheres na pré-menopausa com câncer de mama, análogos do hormônio liberador de gonadotropina podem preservar a função ovariana contra os efeitos gonadotóxicos induzidos pela quimioterapia.

Effects of Gonadotropin-Releasing Hormone Analogs on Ovarian Function Against Chemotherapy-Induced Gonadotoxic Effects in Premenopausal Women With Breast Cancer in China: A Randomized Clinical Trial – JAMA Oncology (link para o resumo – $ para o texto completo)

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Randomized clinical trial finds administration of gonadotropin-releasing hormone analogs (GnRHa) with chemotherapy in premenopausal pts with #BreastCancer reduces risk of premature ovarian insufficiency (#POI) and promotes recovery of ovarian function. https://t.co/gymbKT9GWZ pic.twitter.com/OUOlIwPSsq

— JAMA Oncology (@JAMAOnc) December 30, 2021