Estudo randomizado | Efetividade da terapia com etoposídeo e cisplatina vs. irinotecano e cisplatina para pacientes com carcinoma neuroendócrino avançado do sistema digestório.

Effectiveness of Etoposide and Cisplatin vs Irinotecan and Cisplatin Therapy for Patients With Advanced Neuroendocrine Carcinoma of the Digestive System: The TOPIC-NEC Phase 3 Randomized Clinical Trial – JAMA Oncology

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JCOG1213 (TOPIC NEC), the first randomized phase III trial in advanced neuroendocrine carcinoma of the digestive system, shows no significant difference in overall survival for etoposide+cisplatin versus irinotecan+cisplatin therapy https://t.co/JTELRlzTzi #GICSM pic.twitter.com/AQT8U4yd3l

— JAMA Oncology (@JAMAOnc) August 18, 2022