Estudo randomizado | Efeito da quimioterapia de indução com paclitaxel, cisplatina e capecitabina vs. cisplatina e fluorouracil na sobrevida livre de recorrência para pacientes com carcinoma nasofaríngeo estágios IVA a IVB.

Effect of Induction Chemotherapy With Paclitaxel, Cisplatin, and Capecitabine vs Cisplatin and Fluorouracil on Failure-Free Survival for Patients With Stage IVA to IVB Nasopharyngeal Carcinoma: A Multicenter Phase 3 Randomized Clinical Trial – JAMA Oncology (link para o resumo – $ para o texto completo)

Comentário: Triplet Induction Regimen Bests Doublet for Nasopharyngeal Carcinoma — Three drugs reduced risk of disease failure, but longer follow-up needed to assess OS – MedPage Today (necessário cadastro gratuito)

Comentário no Twitter

Phase 3 randomized trial of paitents with stage IVA to IVB nasopharyngeal carcinoma shows that induction chemotherapy w 2 cycles of paclitaxel/cisplatin/capecitabine improved failure-free survival vs. cisplatin/5-FU before concurrent chemoradiation. https://t.co/YYEvFsTxgd pic.twitter.com/7qbSXLWCE1

— JAMA Oncology (@JAMAOnc) March 24, 2022