Arquivos do dia: Maio 17, 2022
Estudo randomizado | Efeito da posição prona na entubação endotraqueal de pacientes com COVID-19 e insuficiência respiratória aguda.
17 Mai, 2022 | 12:13hConteúdos relacionados:
RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv
Comentário no Twitter
In this trial, in patients with acute hypoxemic respiratory failure from #COVID19, prone positioning, compared with usual care without prone positioning, did not significantly reduce endotracheal intubation at 30 days. https://t.co/1RyYRtcrYj
— JAMA (@JAMA_current) May 15, 2022
Estudo randomizado | Efeito da cistectomia radical assistida por robô com derivação urinária intracorpórea vs. cistectomia radical aberta sobre a morbidade e a mortalidade de 90 dias entre pacientes com câncer de bexiga.
17 Mai, 2022 | 12:11hEditorial: Robotic Surgery for Bladder Cancer – JAMA
Comentário no Twitter
In this trial, robot-assisted surgery vs open surgery for radical cystectomy among patients with #bladdercancer resulted in a statistically significantly greater number of days alive and out of the hospital. https://t.co/icPLiKH0Lf
— JAMA (@JAMA_current) May 15, 2022
Estudo randomizado | Inalador de resgate com dose fixa combinada de albuterol-budesonida para asma.
17 Mai, 2022 | 12:10hAlbuterol–Budesonide Fixed-Dose Combination Rescue Inhaler for Asthma – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentário no Twitter
The risk of severe asthma exacerbation was significantly lower with as-needed use of a fixed-dose combination of 180 μg of albuterol and 160 μg of budesonide than with albuterol alone. #ATS2022 https://t.co/MRGaUaGVwj pic.twitter.com/6BZX9Q6WxX
— NEJM (@NEJM) May 15, 2022
Estudo de um inibidor de fosfodiesterase 4B na fibrose pulmonar idiopática.
17 Mai, 2022 | 12:09hTrial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentário no Twitter
https://twitter.com/NEJM/status/1525878684380430343
Estudo randomizado | Comparação de antibioticoterapia por 8 vs. 15 dias para pneumonia por Pseudomonas aeruginosa associada a ventilador mecânico em adultos.
17 Mai, 2022 | 12:07hComparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial – Intensive Care Medicine (artigo gratuito aqui)
Comentário no Twitter
🧫 8 vs 15 days ABT for Pseudomonas aeruginosa VAP in adults, iDIAPASON RCT: no differences in composite or separate outcomes (90-day mortality/VAP recurrence) between short & long duration treatment.
📢 @yourICM ground-breaking release #LIVES40 #FOAMcc
🖇 https://t.co/LfoUWxCkkl pic.twitter.com/XaWkQ5R6wT— Intensive Care Medicine (@yourICM) May 13, 2022
Posicionamento científico ESC | Cuidado integrado para melhorar o tratamento do AVC e da doença cardíaca associada.
17 Mai, 2022 | 12:06h
Comentário no Twitter
Integrated care for optimizing the management of stroke and associated heart disease: a position paper of the European Society of Cardiology Council on Strokehttps://t.co/L7dPxM6dZx#EHJ #stroke @escardio @ESC_Journals #CardioTwitter pic.twitter.com/MB6mIqzdui
— EHJ Editor-in-Chief (@ehj_ed) May 14, 2022
Sob licença de https://creativecommons.org/licenses/by-nc/4.0/
Estudo de caso-controle e teste negativo | Associação entre vacinação prévia com BNT162b2 contra COVID-19 e infecção sintomática por SARS-CoV-2 em crianças e adolescentes durante a predominância da variante Ômicron.
17 Mai, 2022 | 12:04hEstudo relacionado: Risk of Infection and Hospitalization Among Vaccinated and Unvaccinated Children and Adolescents in New York After the Emergence of the Omicron Variant – JAMA
Editorial: Protecting Children Against Omicron – JAMA
Comentário no Twitter (fio – clique para saber mais)
This new JAMA study is worth discussing. It found that, this winter, vax effectiveness in 12-15 yos dropped to 0% after 3-5 months & vaccinated were MORE likely to test+ at month 7. May be confounded (see🧵)
But I don't see this as good reason for boostershttps://t.co/zpkIDdZhnn pic.twitter.com/bxAIDmiR8s— Tracy Høeg, MD, PhD (@TracyBethHoeg) May 14, 2022
Hipótese | Hepatite aguda grave em crianças: investigação dos superantígenos do SARS-CoV-2.
17 Mai, 2022 | 12:03hConteúdos relacionados:
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Comentário no Twitter
A solid hypothesis for the basis of the mysterious, severe acute hepatitis in children: superantigen formation from prior Covid viral reservoir in the GI tract with superimposed adenovirus infection https://t.co/1eehyQmlhi @LancetGastroHep pic.twitter.com/UqCAh3igMH
— Eric Topol (@EricTopol) May 14, 2022
Recomendações baseadas em evidências para a ultrassonografia pulmonar à beira do leito.
17 Mai, 2022 | 12:01hInternational evidence-based recommendations for point-of-care lung ultrasound – Intensive Care Medicine (se o acesso a este link for pago, tente este)
Diretriz | Supervisão de saúde para crianças e adolescentes com síndrome de Down.
17 Mai, 2022 | 11:59hHealth Supervision for Children and Adolescents With Down Syndrome – Pediatrics