Arquivos do dia: Maio 4, 2022

Remdesivir e 3 outros medicamentos para pacientes internados com COVID-19: resultados finais do estudo randomizado WHO Solidarity e metanálise atualizada.

4 Mai, 2022 | 14:07h

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses – The Lancet

Comentário convidado: When and which patients should receive remdesivir? – The Lancet

---

Estudos randomizados | Efeitos de um programa online de respiração e bem-estar para pessoas com sintomas persistentes após COVID-19.

4 Mai, 2022 | 14:05h

An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trial – The Lancet Respiratory Medicine

Comentário convidado: Treating COVID-19-related breathlessness with novel interventions – The Lancet Respiratory Medicine

Comunicado de imprensa: Singing techniques can improve quality of life and breathlessness after COVID-19 – Imperial College London

 

Comentário no Twitter

NEW Research—Online breathing and wellbeing programme (ENO Breathe) can improve mental
component of HRQoL & elements of breathlessness in #LongCovid

Study from @keirphilip, @COPDdoc, & colleagues https://t.co/Sn0TO6gSev pic.twitter.com/asTiepHhyz

— The Lancet Respiratory Medicine (@LancetRespirMed) April 28, 2022

 

---

Revisão sistemática | Telerreabilitação melhora a função física e reduz a dispneia em pessoas com COVID-19 e condições pós-COVID-19.

4 Mai, 2022 | 14:03h

Telerehabilitation improves physical function and reduces dyspnoea in people with COVID-19 and post-COVID-19 conditions: a systematic review – Journal of Physiotherapy

---

Ponto/Contraponto | Heparina terapêutica deveria ser administrada para pacientes críticos internados com COVID-19?

4 Mai, 2022 | 14:00h

PONTO: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? Yes – CHEST

CONTRPONTO: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? No – CHEST

Ver também: Rebuttal From Dr Tritschler et al – CHEST

Conteúdos relacionados:

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

---

Aterosclerose | Desenvolvimentos recentes.

4 Mai, 2022 | 13:58h

Atherosclerosis: Recent developments – Cell

 

Comentário no Twitter

We've learned a lot about atherosclerosis in recent years, including new genomic underpinnings, role of aging, clonal hematopoiesis, and the gut microbiome. A new, excellent review covers all of the progress and the many residual questionshttps://t.co/nF59sqiB6P @CellCellPress pic.twitter.com/oXVzf4J5XT

— Eric Topol (@EricTopol) May 2, 2022

Sob licença de CC BY 4.0

---

CDC relata o primeiro caso de gripe aviária altamente patogênica (vírus Influenza A H5N1) e emite recomendações.

4 Mai, 2022 | 13:57h

Highly Pathogenic Avian Influenza A(H5N1) Virus: Recommendations for Human Health Investigations and Response – Centers for Disease Control and Prevention

Ver também: U.S. Case of Human Avian Influenza A(H5) Virus Reported – Centers for Disease Control and Prevention

Comentário: Alaska, Oklahoma report first avian flu outbreaks in poultry – CIDRAP

---

M-A de estudos randomizados | Associação entre vacinação contra influenza e risco cardiovascular.

4 Mai, 2022 | 13:55h

Association of Influenza Vaccination With Cardiovascular Risk: A Meta-analysis – JAMA Network Open

 

Comentário no Twitter

In this meta-analysis, seasonal flu vaccine was associated with a 34% reduced risk of major adverse cardiovascular events in 1 year, with the biggest difference in patients with recent acute coronary syndrome. @WCHResearch @PMunkCardiacCtr https://t.co/SPrXNfMQJS

— JAMA Network Open (@JAMANetworkOpen) April 29, 2022

 

---

Perspectiva | Menos farmacoterapia é mais no delirium.

4 Mai, 2022 | 13:54h

Less pharmacotherapy is more in delirium – Intensive Care Medicine (se o acesso a este link for pago, tente este)

Conteúdos relacionados:

Pharmacological interventions for the treatment of delirium in critically ill adults – Cochrane Library

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients – Cochrane Library

Delirium in critical illness: clinical manifestations, outcomes, and management – Intensive Care Medicine

Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review – Critical Care

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis – Intensive Care Medicine

Effectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine

 

Comentário no Twitter

⬇️ 💉Less medications (& ⬆️ awareness of behavioural interventions) is more in #delirium, common, challenging/costly (but often preventable) in #ICU. Despite lacking evidence, medications widely used.
Prevent/minimize addressing suspected contributors!
📎 https://t.co/fYWAsIcuiZ pic.twitter.com/DyC3agSP7w

— Intensive Care Medicine (@yourICM) April 30, 2022

 

---

Diretriz AAP para estruturação de unidade de terapia intermediária pediátrica.

4 Mai, 2022 | 13:52h

Guidance for Structuring a Pediatric Intermediate Care Unit – Pediatrics

---

SUNBURN: protocolo para transmissão de más notícias em trauma e cirurgia de cuidado agudo.

4 Mai, 2022 | 13:51h

SUNBURN: a protocol for delivering bad news in trauma and acute care surgery – Trauma Surgery & Acute Care Open

 

Comentário no Twitter

#TSACOTuesday

Delivery of bad news can be a challenging tasks for practicing surgeons

Protocol-based delivery can provide support to help guide these difficult conversations

S-U-N-B-U-R-N protocol by @DrMentorA provides a framework

Read more: https://t.co/3H5AyT6125 pic.twitter.com/imJ9HuUQJ3

— Trauma Surgery & Acute Care Open (TSACO) (@TSACO_AAST) February 15, 2022

 

---