Acesso livre
Acesso livre

Arquivos do dia: Abril 25, 2022

OMS recomenda o nirmatrelvir-ritonavir para o tratamento da COVID-19 e pede para uma maior distribuição geográfica.

25 Abr, 2022 | 12:47h

WHO recommends highly successful COVID-19 therapy and calls for wide geographical distribution and transparency from originator – World Health Organization

Ver também:

A living WHO guideline on drugs for covid-19 – The BMJ

Therapeutics and COVID-19: living guideline – World Health Organization

Conteúdos relacionados:

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

The COVID-19 Treatment Guidelines Panel’s Statement on Potential Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications – NIH COVID-19 Treatment Guidelines Panel

 

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CDC alerta sobre novos casos de hepatite de origem desconhecida.

25 Abr, 2022 | 12:44h

News Release: CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Ver diretriz: Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Comentários:

CDC issues health advisory about acute hepatitis in children – CNN

CDC Issues Alert for Hepatitis in Children With Adenovirus Infection – WebMD

Conteúdos relacionados:

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press


Seguimento de 1 ano de estudo randomizado | Em pacientes em UTI com hipoxemia grave, não houve diferença na mortalidade de longo prazo e na qualidade de vida relacionada à saúde com alvos de oxigenação mais baixos vs. mais altos.

25 Abr, 2022 | 12:42h

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Estudo original: Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

 

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Regulador de medicamentos do Reino Unido aconselha pacientes e médicos contra o uso de pregabalina durante a gestação em virtude de um possível risco aumentado de malformações congênitas.

25 Abr, 2022 | 12:40h

Pregabalin (Lyrica): findings of safety study on risks during pregnancy – Medicines and Healthcare products Regulatory Agency

Ver também: Pregabalin and risks in pregnancy – Medicines and Healthcare products Regulatory Agency

Fonte: Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator – The BMJ ($)

 

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Análise longitudinal de dados de 15 países | Rigor das políticas e saúde mental durante a pandemia de COVID-19.

25 Abr, 2022 | 12:39h

Policy stringency and mental health during the COVID-19 pandemic: a longitudinal analysis of data from 15 countries – The Lancet Public Health

Comunicado de imprensa: Stricter COVID-19 measures associated with negative mental health effects and lower opinion of government’s pandemic response, new research suggests – The Lancet

Comentário: Stricter Pandemic Policies Took Toll on Mental Health — Women tended to be more affected than men – MedPage Today


M-A | Eficácia clínica dos tratamentos adjuvantes para pacientes com câncer de vias biliares ressecado.

25 Abr, 2022 | 12:37h

Clinical efficacy of adjuvant treatments for patients with resected biliary tract cancer: a systematic review and network meta-analysis – BMJ Open


Revisão | Novos tratamentos para linfomas não Hodgkin de células B.

25 Abr, 2022 | 12:36h

Novel treatments in B cell non-Hodgkin’s lymphomas – The BMJ

 

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Revisão | Estratificação de risco cardiovascular via angiotomografia de coronárias.

25 Abr, 2022 | 12:35h

Cardiovascular risk stratification by coronary computed tomography angiography imaging: current state-of-the-art – European Journal of Preventive Cardiology


Resultados de 96 semanas de estudo randomizado | Eficácia e segurança de dolutegravir ou darunavir combinados com lamivudina e adicionados a zidovudina ou tenofovir como tratamento de segunda linha para infecção pelo HIV.

25 Abr, 2022 | 12:34h

Efficacy and safety of dolutegravir or darunavir in combination with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection (NADIA): week 96 results from a prospective, multicentre, open-label, factorial, randomised, non-inferiority trial – The Lancet HIV

Comentário convidado: Game-changing study of second-line HIV treatment – The Lancet HIV (necessário cadastro gratuito)

Estudo original: Dolutegravir or Darunavir in Combination with Zidovudine or Tenofovir to Treat HIV – New England Journal of Medicine

 

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PRISMA 2020 e PRISMA-S | Questões comuns sobre os registros e diagrama de fluxo.

25 Abr, 2022 | 12:33h

PRISMA 2020 and PRISMA-S: common questions on tracking records and the flow diagram – Journal of the Medical Library Association


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