Arquivos do dia: Abril 25, 2022
OMS recomenda o nirmatrelvir-ritonavir para o tratamento da COVID-19 e pede para uma maior distribuição geográfica.
25 Abr, 2022 | 12:47hVer também:
A living WHO guideline on drugs for covid-19 – The BMJ
Therapeutics and COVID-19: living guideline – World Health Organization
Conteúdos relacionados:
Comentário no Twitter
🔥 Our latest @WHO living guidance on drugs for #COVID19, with new recommendations for nirmatrelvir-ritonavir & updated recommendation for remdesivir in non-severe illness.@bmj_latest: https://t.co/KuJjwzeTPV@WHO: https://t.co/n3iQx3pdmY@theMAGICapp: https://t.co/dA7YYzeAZ1 pic.twitter.com/LvAhJf70UY
— Arnav Agarwal (@ArnavAgarwalMD) April 21, 2022
CDC alerta sobre novos casos de hepatite de origem desconhecida.
25 Abr, 2022 | 12:44hComentários:
CDC issues health advisory about acute hepatitis in children – CNN
CDC Issues Alert for Hepatitis in Children With Adenovirus Infection – WebMD
Conteúdos relacionados:
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Seguimento de 1 ano de estudo randomizado | Em pacientes em UTI com hipoxemia grave, não houve diferença na mortalidade de longo prazo e na qualidade de vida relacionada à saúde com alvos de oxigenação mais baixos vs. mais altos.
25 Abr, 2022 | 12:42hEstudo original: Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine
Comentário no Twitter
Lower (8 kPa) vs higher oxygenation (12 kPa) targets: no longterm survival benefit nor HRQoL improvement at 1y in #ICU pts with severe hypoxaemia (HOT-ICU trial cohort). Substantial impairments in several EQ-5D-5L dimensions in survivors in both groups.
🖇️ https://t.co/P48Cd5sIWK pic.twitter.com/JBFEIqDdcB— Intensive Care Medicine (@yourICM) April 20, 2022
Regulador de medicamentos do Reino Unido aconselha pacientes e médicos contra o uso de pregabalina durante a gestação em virtude de um possível risco aumentado de malformações congênitas.
25 Abr, 2022 | 12:40hVer também: Pregabalin and risks in pregnancy – Medicines and Healthcare products Regulatory Agency
Fonte: Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator – The BMJ ($)
Comentário no Twitter
The Medicines and Healthcare Products Regulatory Agency (@MHRAgovuk) has strengthened its warning about avoiding pregabalin during pregnancy after new data showed an increased risk of major congenital malformations associated with the drug https://t.co/ghGvqCqA0C
— The BMJ (@bmj_latest) April 22, 2022
Análise longitudinal de dados de 15 países | Rigor das políticas e saúde mental durante a pandemia de COVID-19.
25 Abr, 2022 | 12:39hComunicado de imprensa: Stricter COVID-19 measures associated with negative mental health effects and lower opinion of government’s pandemic response, new research suggests – The Lancet
M-A | Eficácia clínica dos tratamentos adjuvantes para pacientes com câncer de vias biliares ressecado.
25 Abr, 2022 | 12:37hRevisão | Novos tratamentos para linfomas não Hodgkin de células B.
25 Abr, 2022 | 12:36hNovel treatments in B cell non-Hodgkin’s lymphomas – The BMJ
Comentário no Twitter
READ: new State of the Art review on novel treatments in B cell non-Hodgkin’s lymphomas.
Learn about mechanisms of action, efficacy and safety, current therapeutic roles, and future directions in treatment https://t.co/EIri6jDBcv
— The BMJ (@bmj_latest) April 22, 2022
Revisão | Estratificação de risco cardiovascular via angiotomografia de coronárias.
25 Abr, 2022 | 12:35hResultados de 96 semanas de estudo randomizado | Eficácia e segurança de dolutegravir ou darunavir combinados com lamivudina e adicionados a zidovudina ou tenofovir como tratamento de segunda linha para infecção pelo HIV.
25 Abr, 2022 | 12:34hComentário convidado: Game-changing study of second-line HIV treatment – The Lancet HIV (necessário cadastro gratuito)
Estudo original: Dolutegravir or Darunavir in Combination with Zidovudine or Tenofovir to Treat HIV – New England Journal of Medicine
Comentário no Twitter
Efficacy and safety of DTG or DRV in combination with 3TC + ZDV or TDF for second-line treatment of HIV infection (NADIA)… https://t.co/XajA2rLzsp DTG & DRV-based ART maintain good viral suppression during 96 wks; DTG non-inferior to DRV but ⬆️risk of resistance in 2rd-line Rx.
— Carlos del Rio (@CarlosdelRio7) April 21, 2022