Acesso livre
Acesso livre

Arquivos do dia: Abril 18, 2022

Análise observacional em Israel mostrou que a 4ª dose da vacina da Pfizer pode reduzir o risco de curto prazo dos desfechos adversos relacionados a Covid-19.

18 Abr, 2022 | 15:31h

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

Editorial: Covid-19 Boosters — Where from Here?

Conteúdos relacionados:

COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines.

Observational study suggests a fourth dose of the Pfizer vaccine provided additional protection against severe disease in patients 60 years of age or older during the Omicron wave in Israel.

Perspective: The evidence on 4th doses of covid vaccines & the thorny question of age thresholds.

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

Covid-19: Fourth vaccine doses—who needs them and why?

[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

 

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Covid-19: qual é a evidência para o uso do antiviral molnupiravir?

18 Abr, 2022 | 15:30h

Covid-19: What is the evidence for the antiviral molnupiravir? – The BMJ

Estudo mostrou baixas taxas de COVID-19 grave em crianças internadas com infecção por SARS-CoV-2 confirmada.

18 Abr, 2022 | 15:29h

Very low rates of severe COVID-19 in children hospitalised with confirmed SARS-CoV-2 infection in London, England – Journal of Infection

Comentário: Severe COVID-19 extremely rare among children – News Medical

Conteúdos relacionados:

[Preprint] Risk of Hospitalization, severe disease, and mortality due to COVID-19 in children with SARS-CoV-2 infection in Germany – “overall hospitalization rate associated with SARS-CoV-2 infection was 35.9 per 10,000 children, ICU admission rate was 1.7 per 10,000 and case fatality was 0.09 per 10,000”.

Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year – “In total, 99.995% of children and young people with a positive SARS-CoV-2 test survived”.

Editorial: COVID-19 vaccines for children – “Although it is true that most children experience asymptomatic or mild disease, some will get quite sick, and a small number will die. It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis”.

COVID-19 disease severity in children infected with the Omicron variant.

Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year.

Study identifies risk factors for severe CoviD-19 in children.

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

International study identifies predictors of severe outcomes in children with COVID-19.

Análise dos especialistas | O papel da pericardiotomia esquerda posterior na redução da efusão pericárdica e da fibrilação atrial pós-operatória após cirurgia cardíaca.

18 Abr, 2022 | 15:27h

The Role of the Posterior Left Pericardiotomy in Reducing Pericardial Effusion and Postoperative Atrial Fibrillation After Cardiac Surgery – American College of Cardiology

Estudo relacionado dos mesmos autores: #AHA21 – RCT: Among patients undergoing cardiac surgery, routine posterior left pericardiotomy can prevent postoperative atrial fibrillation.

 

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Estudo randomizado | Eficácia, segurança e imunogenicidade de uma vacina de enterovírus 71 inativado em bebês e crianças.

18 Abr, 2022 | 15:26h

Efficacy, safety, and immunogenicity of an inactivated, adjuvanted enterovirus 71 vaccine in infants and children: a multiregion, double-blind, randomised, placebo-controlled, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)

Série Lancet | Origens da doença pulmonar obstrutiva crônica.

18 Abr, 2022 | 15:25h

Página principal: Origins of chronic obstructive pulmonary disease – The Lancet Respiratory Medicine (necessário cadastro gratuito para todos os artigos)

Genetics of chronic obstructive pulmonary disease: understanding the pathobiology and heterogeneity of a complex disorder

Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment

Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan

GETting to know the many causes and faces of COPD

COPD, smoking, and social justice

 

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Opinião | A grande ideia: deveríamos desistir dos artigos científicos? – “Como um formato, é lento, fortalece exageros e é difícil de corrigir. Uma mudança radical das publicações poderia melhorar a ciência.”

18 Abr, 2022 | 15:23h

The big idea: should we get rid of the scientific paper? – The Guardian

M-A | Associação entre atividade física e risco de depressão.

18 Abr, 2022 | 15:22h

Association Between Physical Activity and Risk of Depression: A Systematic Review and Meta-analysis – JAMA Psychiatry

Comentário: Exercise Is Powerful Medicine for Depression – HealthDay

 

Comentário no Twitter

 

Estudo transversal | Uso de inibidores seletivos de recaptação de serotonina está associado com redução de movimentos medidos.

18 Abr, 2022 | 15:20h

Association of Selective Serotonin Reuptake Inhibitor Use With Abnormal Physical Movement Patterns as Detected Using a Piezoelectric Accelerometer and Deep Learning in a Nationally Representative Sample of Noninstitutionalized Persons in the US – JAMA Network Open

 

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Estudo de coorte | Tipo sanguíneo não O está associado a risco aumentado de tromboembolismo venoso em pacientes com câncer.

18 Abr, 2022 | 15:19h

ABO blood group type and risk of venous thromboembolism in patients with cancer – Blood Advances (link para o resumo – $ para o texto completo)

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