Arquivos do dia: Março 8, 2022

Diretriz Científica AHA | Interações medicamentosas na cárdio-oncologia.

8 Mar, 2022 | 18:41h

Cardio-Oncology Drug Interactions: A Scientific Statement From the American Heart Association – Circulation

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Estudo randomizado | Azitromicina não é efetiva na prevenção de sibilo recorrente após bronquiolite grave causada por vírus sincicial respiratório.

8 Mar, 2022 | 18:40h

Azithromycin to Prevent Recurrent Wheeze Following Severe Respiratory Syncytial Virus Bronchiolitis – NEJM Evidence

Comentários:

Study finds azithromycin use during RSV not useful in preventing recurrent wheezing, may cause harm – Vanderbilt University Medical Center

Antibiotic doesn’t prevent future wheezing in babies hospitalized with RSV – Washington University in St. Louis

 

Comentário no Twitter

This RCT tested oral azithromycin vs placebo to reduce recurrent wheeze (RW) in 1-18-month-olds hospitalized with acute severe RSV bronchiolitis. Azithromycin did not reduce occurrence of RW and may increase risk of RW in some groups. #AAAAI22 #Asthma #EBM https://t.co/jYcBuiQ8aY pic.twitter.com/u65NbQaIlX

— NEJM Evidence (@NEJMEvidence) February 28, 2022

 

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Fazer mais pode ser pior: 10 erros comuns em UTI.

8 Mar, 2022 | 18:38h

Doing More Can Be Worse: Ten Common Errors in the ICU – ICU Management & Practice

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Estudo randomizado | Rastreamento para fibrilação atrial em idosos por meio de ECG de derivação única não aumentou as taxas de detecção em 1 ano.

8 Mar, 2022 | 18:38h

Screening for Atrial Fibrillation in Older Adults at Primary Care Visits: the VITAL-AF Randomized Controlled Trial – Circulation (link to abstract – $ for full-text)

Conteúdos relacionados:

USPSTF Recommendation Statement: Still not enough evidence to recommend atrial fibrillation screening.

#ESCCongress – RCT: In individuals at risk for stroke, screening for atrial fibrillation using loop recorder resulted in a three-times increase in atrial fibrillation detection and anticoagulation initiation but did not reduce the risk of stroke or systemic arterial embolism.

#ESCCongress – RCT: Small benefit from systematic screening for atrial fibrillation in older adults – After a median follow-up of 6.9 y there were fewer events (stroke, embolism, bleeding, and death) in the intervention group (31·9%) vs. control group (33·0%).

Clinical Review: Screening and management of atrial fibrillation in primary care

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Estudo mostra que o número de infecções por Covid-19 não identificadas por testes de fluxo lateral é “substancial o bastante para ter importância clínica.”

8 Mar, 2022 | 18:36h

Comunicado de imprensa: Number of covid-19 infections missed by lateral flow tests “substantial enough to be of clinical importance,” warn experts – BMJ

Estudo original: SARS-CoV-2 antigen lateral flow tests for detecting infectious people: linked data analysis – The BMJ

Comentários:

Lateral flow tests may be missing ‘substantial’ number of COVID-19 infections – Imperial College London

Self-testing for asymptomatic non-contacts using rapid antigen tests—is this leading to a cost effective reduction in infection transmission? – The BMJ

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Dois imunologistas explicam quanto tempo dura a imunidade protetora contra COVID-19 após infecção ou vacinação.

8 Mar, 2022 | 18:34h

How long does protective immunity against COVID-19 last after infection or vaccination? Two immunologists explain – The Conversation

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A próxima variante: 3 questões centrais sobre o que vem depois da Ômicron.

8 Mar, 2022 | 18:33h

The next variant: three key questions about what’s after Omicron – Nature

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[Comunicado de imprensa – ainda não publicado] Nova vacina da Sanofi e GSK demonstra forte proteção contra Covid-19 grave.

8 Mar, 2022 | 18:32h

Comentário: New vaccine demonstrates strong protection against severe Covid-19 in clinical trials – CNN

Comunicado de imprensa: Sanofi and GSK to seek regulatory authorization for COVID-19 vaccine

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Revista Nature está testando maior transparência nas revisões por pares – Os resultados iniciais são encorajadores.

8 Mar, 2022 | 18:30h

Nature is trialling transparent peer review — the early results are encouraging – Nature

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Atualização do CDC e da AAP nos marcos de desenvolvimento em crianças para programa de vigilância.

8 Mar, 2022 | 18:26h

Comunicado de imprensa: CDC, AAP update developmental milestones for surveillance program – AAP News

Ver diretriz: Evidence-Informed Milestones for Developmental Surveillance Tools – Pediatrics

Comentários:

Revised Developmental Milestone Guidelines For Infants And Toddlers: Explained Here – Forbes

Much Awaited – Development Milestone Checklists Updated by CDC & AAP – Pediatric OnCall

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