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Arquivos do dia: Novembro 10, 2021

Estudo randomizado | Vacina da Pfizer mostra 90,7% de eficácia na prevenção de Covid-19 em crianças de 5 a 11 anos de idade.

10 Nov, 2021 | 12:55h

Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age – New England Journal of Medicine

 

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Como um surto se tornou uma pandemia: análise cronológica de conjunturas cruciais e obrigações internacionais nos meses iniciais da pandemia de COVID-19.

10 Nov, 2021 | 12:53h

How an outbreak became a pandemic: a chronological analysis of crucial junctures and international obligations in the early months of the COVID-19 pandemic – The Lancet

 

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[Preprint] Estudo randomizado | Em pacientes com COVID-19 com hipoxemia, mas não críticos, uma intervenção para estimular o decúbito em prona não melhorou os desfechos.

10 Nov, 2021 | 12:52h

RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv

Conteúdos relacionados:

RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.

RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared to standard care.

M-A: Prone positioning of nonintubated patients with Covid-19 improve oxygenation variables without any reported serious adverse events – randomized trials with patient-relevant outcomes such as the need for intubation or mortality rates are required

 

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Autoridade de saúde da França faz recomendações contra o uso da vacina da Moderna em menores de 30 anos de idade.

10 Nov, 2021 | 12:50h

French Health Authority Advises Against Moderna COVID-19 Vaccine for Under 30s – Reuters

Ver também: France advises against Moderna for under-30s over rare heart risk – Associated Press

Conteúdo relacionado: Sweden, Denmark pause Moderna COVID-19 vaccine for younger age groups.

 

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Opinião | Imunidade após recuperação de infecção por SARS-CoV-2.

10 Nov, 2021 | 12:48h

Protective immunity after recovery from SARS-CoV-2 infection – The Lancet Infectious Diseases

 

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Um proeminente virologista alerta que a nova pílula contra COVID-19 pode gerar perigosas mutações no vírus. Outros não veem com tanto alarde.

10 Nov, 2021 | 12:47h

A prominent virologist warns COVID-19 pill could unleash dangerous mutants. Others see little cause for alarm – Science

Ponto de vista original: Supercharging New Viral Variants: The Dangers Of Molnupiravir (Part 1) – Forbes

Conteúdos relacionados:

The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.

Merck to allow other nations to produce new COVID-19 antiviral.

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.


Consenso | Exames de imagem não invasivos em síndromes coronarianas.

10 Nov, 2021 | 12:45h

Non-invasive Imaging in Coronary Syndromes — Recommendations of the European Association of Cardiovascular Imaging and the American Society of Echocardiography, in Collaboration with the American Society of Nuclear Cardiology, Society of Cardiovascular Computed Tomography and Society for Cardiovascular Magnetic Resonance – European Heart Journal: Cardiovascular Imaging


Consenso | Multimodalidade de exames de imagem em pacientes com insuficiência cardíaca e fração de ejeção preservada.

10 Nov, 2021 | 12:44h

Multimodality imaging in patients with heart failure and preserved ejection fraction: an expert consensus document of the European Association of Cardiovascular Imaging – European Heart Journal: Cardiovascular Imaging


Diretriz | Tratamento não farmacológico de sintomas persistentes pós-concussão em adultos.

10 Nov, 2021 | 12:43h

Nonpharmacological Treatment of Persistent Postconcussion Symptoms in Adults: A Systematic Review and Meta-analysis and Guideline Recommendation – JAMA Network Open

Comentário convidado: Advances in Clinical Management of Persistent Postconcussion Symptoms—The Danish National Clinical Guideline – JAMA Network Open

 

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Estudo randomizado | Rastreamento com sigmoidoscopia flexível uma única vez está associado com redução, no longo prazo, da incidência e mortalidade por câncer colorretal.

10 Nov, 2021 | 12:41h

Long-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial – Annals of Internal Medicine

Comentários:

Flexible sigmoidoscopy associated with long-term reduction in colorectal cancer incidence, mortality – ACP Internist

Flexible sigmoidoscopy screening associated with long-term reduction in colorectal cancer incidence and mortality – American College of Physicians


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