Arquivos do dia: Outubro 12, 2021

Nova análise do Global Burden of Disease Study mostra depressão e ansiedade entre as principais causas mundiais de impacto de saúde, além de um aumento significativo decorrente da pandemia de COVID-19.

12 Out, 2021 | 11:24h

Comunicado de imprensa: New Global Burden of Disease analyses show depression and anxiety among the top causes of health burden worldwide, and a significant increase due to the COVID-19 pandemic – Institute for Health Metrics and Evaluation

Estudo original: Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic – The Lancet

Comentários:

Depression and anxiety disorders during the COVID-19 pandemic: knowns and unknowns – The Lancet

COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020: study – The Lancet

Covid crisis dramatically worsened global mental health, study finds – The Guardian

 

Comentário no Twitter (fio – clique para saber mais)

✨🆕–The #COVID19 pandemic led to a stark rise in depressive and anxiety disorders globally in 2020 w/women & younger people most affected, according to a new study by our researchers & collaborators published today in @TheLancet. #GBDstudy #MentalHealth

»https://t.co/qXEDzn3idV pic.twitter.com/4xsofBXyvS

— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) October 8, 2021

 

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Estudo randomizado | Dose terapêutica de heparina se mostrou superior à dose profilática ou à dose intermediária para tromboprofilaxia em pacientes de alto risco internados com COVID-19.

12 Out, 2021 | 11:22h

Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19: The HEP-COVID Randomized Clinical Trial – JAMA Internal Medicine

Comentário convidado: Anticoagulant Therapy in Patients Hospitalized With COVID-19 – JAMA Internal Medicine

Estudos relacionados (alguns resultados conflitantes)

Another meta-analysis suggests standard-dose prophylactic anticoagulation is the best option for patients hospitalized with Covid-19.

M-A: Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19 – According to this analysis, standard-dose prophylactic anticoagulation should be the standard of care for hospitalized patients with COVID-19 who do not have an indication for therapeutic anticoagulation, irrespective of disease severity.

RCT: In noncritically ill patients hospitalized with Covid-19, therapeutic-dose anticoagulation with heparin increased the probability of survival to hospital discharge compared with usual-care thromboprophylaxis.

RCT: In critically ill patients with Covid-19, therapeutic anticoagulation with heparin did not result in improved outcomes compared to usual-care pharmacologic thromboprophylaxis.

RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased bleeding risk.

 

Comentário no Twitter

Thromboprophylaxis w therapeutic-dose LMWH reduced major thromboembolism and death by 32% compared with institutional standard heparin without increased major bleeding among #COVID19 inpatients with elevated D-dimers. The effect wasn't seen in ICU patients https://t.co/Wrgj2Ho5lv

— JAMA Internal Medicine (@JAMAInternalMed) October 7, 2021

 

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Crianças estão perdendo dias de aula para a quarentena. Há um meio de mantê-las nas aulas – “Realizar testes frequentes poderia reduzir drasticamente a quarentena de contatos próximos.”

12 Out, 2021 | 11:20h

Kids are losing school days to quarantines. Here’s a way to keep them in classrooms – NPR

Estudo relacionado: Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

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Bioética | O “problema do bonde” e a vacinação de jovens contra a COVID-19.

12 Out, 2021 | 11:18h

The Trolley Problem and Vaccinating Young People Against COVID-19 – Science-Based Medicine

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[Preprint] COVID-19 em crianças, decorrente da cepa Delta do SARS-CoV-2, é semelhante à doença causada pela variante Alfa, com curta duração e sintomas similares.

12 Out, 2021 | 11:16h

Illness characteristics of COVID-19 in children infected with the SARS-CoV-2 Delta variant – medRxiv

 

Comentário no Twitter

Did you hear “Delta is different”, when it comes to #COVID19 symptom severity in children?

GOOD NEWS 🥳

Turns out there is barely any difference at all between Delta and Alpha in symptom duration, severity, or risk of “long covid”

Myth busted 💥 https://t.co/iPd9AedXaS

— Alasdair Munro (@apsmunro) October 7, 2021

 

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É muito baixo o risco de inflamação cardíaca após vacina da Pfizer contra COVID.

12 Out, 2021 | 11:15h

Heart-inflammation risk from Pfizer COVID vaccine is very low – Nature

Estudos originais:

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

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Relatório da OMS destaca o déficit global nos investimentos em saúde mental.

12 Out, 2021 | 11:12h

WHO report highlights global shortfall in investment in mental health – World Health Organization

Relatório: Mental Health ATLAS 2020 – World Health Organization

Ver também: World Mental Health Day 2021: Mental health care for all: let’s make it a reality – World Health Organization

 

Comentário no Twitter (fio – clique para saber mais)

The world has failed to provide people with the #MentalHealth services they need: new Mental Health Atlas
Read more➡️https://t.co/J0uKvKWZ46 pic.twitter.com/0wKx6JTV2F

— World Health Organization (WHO) (@WHO) October 8, 2021

 

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Dia Mundial da Saúde Mental: priorizar a justiça social, não somente o acesso ao cuidado.

12 Out, 2021 | 11:11h

World Mental Health Day: prioritise social justice, not only access to care – The Lancet (necessário cadastro gratuito)

 

Comentário no Twitter

"…under the wrong set of social circumstances, everyone is vulnerable to mental health problems."#WorldMentalHealthDay: prioritise social justice, not only access to care—a Comment by Soumitra Pathare @netshrink and colleagues. https://t.co/AwdSXo8y5H pic.twitter.com/Az6AB9vLmm

— The Lancet (@TheLancet) October 10, 2021

 

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Editorial | Saúde cerebral e seus determinantes sociais.

12 Out, 2021 | 11:10h

Brain health and its social determinants – The Lancet

 

Comentário no Twitter

Globally, action to tackle the social determinants of mental ill health—including poverty, racism, and discrimination—remains a low priority in too many countries.

On #WorldMentalHealthDay, read our Editorial: https://t.co/VRJkZ8kVn5#MentalHealth #WMHD2021 pic.twitter.com/hxvrCoMbt0

— The Lancet (@TheLancet) October 10, 2021

 

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M-A | Acurácia do Questionário sobre Saúde do Paciente-9 para rastreamento e detecção de depressão maior.

12 Out, 2021 | 11:08h

Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression: updated systematic review and individual participant data meta-analysis – The BMJ

Ver calculadora: PHQ-9 (Patient Health Questionnaire-9)

 

Comentário no Twitter

This new study investigates the accuracy of the Patient Health Questionnaire-9 (PHQ-9), the most commonly used depression screening tool in general practice, for detecting major depression https://t.co/9WoI3MofWH

— The BMJ (@bmj_latest) October 10, 2021

 

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