Arquivos do dia: Outubro 8, 2021

Diretriz OMS | Detecção por antígeno no diagnóstico da infecção por SARS-CoV-2.

8 Out, 2021 | 12:33h

Antigen-detection in the diagnosis of SARS-CoV-2 infection – World Health Organization

Infográficos relacionados:

Use of antigen detection rapid diagnostic testing – World Health Organization

Diagnostic testing for SARS-CoV-2 infection – World Health Organization

 

Comentário no Twitter (fio – clique para saber mais)

Testing remains a critical component to the strategy to end the #COVID19 pandemic, and testing needs to be reliable, accessible, affordable, fast and linked to public health action.

So many around 🌍 have worked hard to increase testing capacities @WHOhttps://t.co/VDPdU0VK4g

— Maria Van Kerkhove (@mvankerkhove) October 7, 2021

 

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Consenso OMS | Definição de caso clínico da condição pós-COVID-19 (“long Covid”).

8 Out, 2021 | 12:31h

A clinical case definition of post COVID-19 condition by a Delphi consensus, 6 October 2021 – World Health Organization

Conteúdos relacionados:

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (vários artigos sobre o tema)

 

Comentário no Twitter (fio – clique para saber mais)

🆕 WHO clinical case definition for post #COVID19 condition, also called 'long COVID' https://t.co/WoiLcwsgJX pic.twitter.com/Z0olrHlWPC

— World Health Organization (WHO) (@WHO) October 7, 2021

 

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OMS lança estratégia para atingir a vacinação global contra Covid-19 até meados de 2022.

8 Out, 2021 | 12:28h

Strategy to Achieve Global Covid-19 Vaccination by mid-2022 – World Health Organization

Comunicado de imprensa: WHO, UN set out steps to meet world COVID vaccination targets – World Health Organization

Comentários:

WHO Believes 70% Vaccination Target is Possible – But Only if Wealthy Countries Make Way for COVAX and Africa – Health Policy Watch

WHO launches global COVID vaccination strategy – CIDRAP

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Estudo mostra risco aumentado de síndrome de Guillain-Barré após vacina da J&J; a razão de taxas foi de 4,18 para uma janela de 42 dias.

8 Out, 2021 | 12:27h

Association of Receipt of the Ad26.COV2.S COVID-19 Vaccine With Presumptive Guillain-Barré Syndrome, February-July 2021 – JAMA

 

Comentário no Twitter

Study suggests a potential small but statistically significant safety concern for #GuillainBarré syndrome following receipt of the @JanssenUS #COVID19 vaccine; findings considered preliminary pending analysis of medical records to establish a definitive Dx https://t.co/yZjJVkp6BA

— JAMA (@JAMA_current) October 7, 2021

 

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Dados de mundo real mostram reatogenicidade aumentada em adultos após vacinação heteróloga em comparação à homóloga contra COVID-19.

8 Out, 2021 | 12:25h

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination, March−June 2021, England – Eurosurveillance

Conteúdos relacionados:

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

 

Comentário no Twitter

As more & more countries consider adding a 3rd #COVID19 vaccine dose into their national immunisation programmes, vaccine reactogenicity will become important, especially if 3rd dose is different to first 2 doses. We need more mix-n-match booster studies 👉https://t.co/G57i9Ej7Nd

— Shamez Ladhani (@ShamezLadhani) October 7, 2021

 

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Como o risco de Covid-19 em crianças se compara a outros perigos.

8 Out, 2021 | 12:23h

How the risk of Covid-19 for kids compares to other dangers – Vox

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Ivermectina: como a falsa ciência criou um medicamento “milagroso” para a Covid.

8 Out, 2021 | 12:21h

Ivermectin: How false science created a Covid ‘miracle’ drug – BBC

 

Comentário no Twitter

Scientists evaluating ivermectin data for #COVID19
"had not found 'a single clinical trial' claiming to show that ivermectin prevented Covid deaths that did not contain 'either obvious signs of fabrication or errors so critical they invalidate the study'." https://t.co/Xndr6Q5LaS

— Isaac Bogoch (@BogochIsaac) October 7, 2021

 

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Bioética | Hospital afirma que pessoas que querem transplante de órgãos devem se vacinar contra a COVID-19.

8 Out, 2021 | 12:20h

People who want organ transplants must get the COVID-19 vaccine, a hospital say – NPR

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Opinião | A Covid-19 segue dando lições sobre o burnout nos profissionais da atenção à saúde. Será que vamos aprendê-las?

8 Out, 2021 | 12:19h

Covid-19 keeps delivering lessons about health care worker burnout. Will we learn them? – STAT

 

Comentário no Twitter

Opinion: Delaying the important work of addressing burnout under the guise of "let's just get through this first" does a disservice to health care workers who need support and relief now. https://t.co/21s5NRvhdk

— STAT (@statnews) October 7, 2021

 

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Diretrizes alemãs para o tratamento de distúrbios de ansiedade.

8 Out, 2021 | 12:17h

The German Guidelines for the treatment of anxiety disorders: first revision – European Archives of Psychiatry and Clinical Neuroscience

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