Arquivos do dia: Agosto 9, 2021
Estudo randomizado | Segurança e imunogenicidade de esquemas de segunda dose heterólogos vs. homólogos de vacinas contra COVID-19 com vetor adenoviral vs. de mRNA.
9 Ago, 2021 | 11:40hComentário convidado: Optimising SARS-CoV-2 vaccination schedules – The Lancet
Conteúdo relacionado: Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination (vários artigos sobre o tema)
Comentário no Twitter
Just published @TheLancet
A randomized mix and match trial of AZ and Pfizer vaccination in >800 people shows that mixing is safe and can engender at least as good, if not better, immune response https://t.co/V40Dy59Ia8 by @XinxueLiu and colleagues pic.twitter.com/tKl59LFz4i— Eric Topol (@EricTopol) August 6, 2021
Estudo do CDC mostrou um risco reduzido de reinfecção por SARS-CoV-2 após vacinação contra Covid-19.
9 Ago, 2021 | 11:37h
Comentários no Twitter
This is non randomized. The two biases are:
1. Behavior among those who got vaccinated likely different than those who don't
2. Likely those who didn't tested more aggressively
I would not cite this as many are doinghttps://t.co/rSkBC37uq0
— Vinay Prasad, MD MPH 🎙️📷 (@VPrasadMDMPH) August 7, 2021
Study shows that full #COVIDVaccination ⬇️ likelihood of being re-infected with #COVID19 compared to those who were previously had COVID but were not vaccinated (risk ⬆️ 2.3 fold)#GetVaccinated even if you have had COVID previouslyhttps://t.co/3dF3XPxwYp@fascinatorfun pic.twitter.com/ip6zTvNN86
— Kamlesh Khunti (@kamleshkhunti) August 7, 2021
Infográfico interativo | Dados mostram como são raras as infecções graves por Covid em indivíduos plenamente vacinados.
9 Ago, 2021 | 11:36hData shows how rare severe breakthrough Covid infections are – NBC News
Comentário no Twitter
Very good interactive infographic for impact of vaccination in 2021 by state https://t.co/HAfYYPX9FI by @NBCNews @seenigel @ChicagoEl @pdrbarquinha @jiachuanwu @NBCNewsGraphics
Here for California: Hospitalizations, deaths and infections pic.twitter.com/83Hxl2x2gm— Eric Topol (@EricTopol) August 7, 2021
M-A | Taxas de transmissão do SARS-CoV-2 nos diversos ambientes – “Contatos domiciliares mostraram os maiores índices de transmissão, com taxas de transmissão secundária de 21,1%.”
9 Ago, 2021 | 11:35h
Comentário no Twitter
SARS-CoV-2 setting-specific transmission rates: a systematic review and meta-analysis
Households highest transmission rates, pooled SAR~21.1%. Contacts at social events~5.9%. Workplaces~1.9%. Age gradient for transmission potential in h/hold context. https://t.co/m27kkDrTgy
— Andrew Lee (@andrewleedr) March 10, 2021
Tóquio temia que os Jogos Olímpicos disseminassem o COVID; os números sugerem que isso não ocorreu.
9 Ago, 2021 | 11:33hTokyo feared Games would spread COVID; numbers suggest that didn’t happen – Reuters
Comentário no Twitter
Before the #Olympics began, Japan feared that the Games might spread COVID-19, introduce new variants and overwhelm the medical system. The infection numbers from inside the Olympic 'bubble' tell a different story https://t.co/EsIxj3gsNx
— Reuters (@Reuters) August 7, 2021
COVID: OMS propõe uma pausa temporária nas doses de reforço para poder vacinar os países mais pobres – isso é justificável?
9 Ago, 2021 | 11:32hCOVID: WHO calls for moratorium on booster shots – is it justifiable? – The Conversation
Conteúdo relacionado: Covid: WHO calls for booster pause to vaccinate poorer nations.
Comentário no Twitter
The authors put it well: Even if affluent countries prioritize boosters for the vulnerable, 'the degree of additional benefit…is uncertain.' Yet we know 'vaccines could do a huge amount of good for the large number of vulnerable ppl who've not yet received a single dose.' https://t.co/6qNV6pzDDk
— Tedros Adhanom Ghebreyesus (@DrTedros) August 7, 2021
Reforços da vacina contra COVID: questões mais importantes.
9 Ago, 2021 | 11:30hCOVID vaccine boosters: the most important questions – Nature
Comentário no Twitter
I agree with @nataliexdean: “We just don’t have clear evidence of enough of a loss of efficacy to change our focus or distract from the main goal, which is trying to get as many people first doses” as possible." https://t.co/FEKB4vg0Dz
— Sanghyuk Shin (@sanghyuk_shin) August 6, 2021
Mais dados mostram que uma dose da vacina da Pfizer pode ser suficiente para pessoas que já tiveram COVID.
9 Ago, 2021 | 11:29hComentário: One Dose of Pfizer Vaccine May Be Enough for Folks Who’ve Had COVID – HealthDay
Estudo original: SARS-CoV-2 Antibody Responses in Infection-Naive or Previously Infected Individuals After 1 and 2 Doses of the BNT162b2 Vaccine – JAMA Network Open
Conteúdos relacionados:
Perspective | Is one vaccine dose enough if you’ve had COVID? What the science says.
Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19
Spain to give just one vaccine dose to under 55-year olds who had COVID-19
Perspective: Is one vaccine dose enough after COVID-19 infection?
France’s health authority recommends single vaccine shot for people who have had COVID-19
Covid-19: People who have had infection might only need one dose of mRNA vaccine
Comentário no Twitter
SARS-CoV-2 Antibody Responses After 1 and 2 Doses of the BNT162b2 Vaccine https://t.co/ARMdH8Yboo via @JAMANetworkOpen part of @JAMANetwork Small study but one that confirms the policy of many European countries in which one dose of vaccine is sufficient after having COVID.
— Carlos del Rio (@CarlosdelRio7) August 7, 2021
Relato de caso | Síndrome de vazamento capilar sistêmico após vacinação com a vacina da Oxford–AstraZeneca.
9 Ago, 2021 | 11:27hAdaptação de intervenções para novos contextos – A diretriz ADAPT: “O uso de intervenções baseadas em evidência previa em novos contextos pode ser mais eficaz do que desenvolver novas intervenções.”
9 Ago, 2021 | 11:25hAdapting interventions to new contexts—the ADAPT guidance – The BMJ
Comentário no Twitter
"Although some interventions transfer well, effectiveness and implementation often depend on the context."
This paper presents new evidence and consensus informed guidance for adapting and transferring interventions to new contextshttps://t.co/of1ojFR6VD
— The BMJ (@bmj_latest) August 8, 2021