Arquivos do dia: Maio 17, 2021
Estudo RECOVERY: Não há benefício no uso de plasma convalescente em pacientes com COVID-19 admitidos em hospital.
17 Mai, 2021 | 09:50hComentário convidado: Convalescent plasma in patients hospitalised with COVID-19
Comentários no Twitter
Convalescent plasma:
Yet another example of
Don’t guess, don’t gamble
Randomize… and learn
I’ve heard it said that it was deemed “too difficult” to do a randomised controlled trial. Really? If that’s the case, we must (and can) fix that problem. Pts deserve better. https://t.co/zxIiK5U63v
— Martin Landray (@MartinLandray) May 15, 2021
NEW #COVID19 research—In patients hospitalised with COVID-19, high-titre convalescent plasma did not improve survival or other prespecified clinical outcomes. Read https://t.co/7Sbe8V9THp. #RECOVERY #RECOVERYtrial pic.twitter.com/D0OLZKxZc4
— The Lancet (@TheLancet) May 16, 2021
Vigilância de doenças para a era COVID-19: hora de mudanças ousadas.
17 Mai, 2021 | 09:49hDisease surveillance for the COVID-19 era: time for bold changes – The Lancet
Comentário no Twitter
Together with esteemed colleagues, we call for bold changes for disease surveillance in the COVID-19 era and beyond.
The time to act is now, but it will require courage, leadership and more collaboration than ever before.https://t.co/s3vL9jt68G pic.twitter.com/ZKBu7wmKNJ
— Chikwe Ihekweazu (@Chikwe_I) May 15, 2021
[Preprint] Aumentar o intervalo para a segunda dose da vacina da Pfizer para 12 semanas aumenta em 3,5 vezes a resposta anticorpo-específica em pessoas com mais de 80 anos de idade.
17 Mai, 2021 | 09:47hComunicado de imprensa: Delaying second Pfizer vaccines to 12 weeks significantly increases antibody responses in older people, finds study – University of Birmingham
Comentários: Delaying a COVID vaccine’s second dose boosts immune response – Nature E Delaying Second Pfizer COVID-19 Vaccine Dose Increases Antibody Response Threefold In Over-80s, Study Finds – Health Policy Watch E Delay in giving second jabs of Pfizer vaccine improves immunity – The Guardian E Expert reaction to preprint looking at the immune response in older people after vaccination the Pfizer-BioNTech COVID-19 vaccine with either a 3-week or a 12-week dosing schedule – Science Media Centre
Estudo: Retardar a aplicação da segunda dose das vacinas mRNA da Pfizer-BioNTech e da Moderna pode reduzir as mortes em até 20% sob determinadas condições.
17 Mai, 2021 | 09:46hComentários: Expert reaction to study looking at the public health impact of delaying the second dose of the Pfizer-BioNTech and Moderna COVID-19 vaccines – Science Media Centre E Delaying second Covid vaccine doses can save lives, study finds – The Guardian E Delaying second COVID vaccine dose may prevent deaths under certain conditions – The BMJ
#ACC21 – [Ainda não publicado] Estudo randomizado – DARE-19: Dapaglifozina é segura, mas não melhora significativamente o desfecho entre pacientes de alto risco hospitalizados com COVID-19.
17 Mai, 2021 | 09:43hVer também: Dapagliflozin in Respiratory Failure in Patients With COVID-19 – DARE-19 – American College of Cardiology
Comentários no Twitter
DARE-19 trial #ACC21 @ACCinTouch
Dapa did not reduce clinical endpoints in #COVID19, but excellent safety profile
🎯 Do not discontinue SGLT2i in 🏥 for #COVID19
Full slideset available in 👇https://t.co/RPi5mpPbbN pic.twitter.com/B9VQdSSAFu
— Enrique Santas (@SantasEnrique) May 16, 2021
DARE-19 findings presented at #ACC21 show #dapagliflozin didn’t significantly ⬇️ risk of organ failure or death or improve recovery in patients hospitalized w/ #COVID19. However, data suggest the SGLT2 inhibitor was well tolerated in acutely ill patients. https://t.co/YjYxbuc952 pic.twitter.com/J4PqwvGpLJ
— American College of Cardiology (@ACCinTouch) May 16, 2021
Perspectiva: Não existe “coração de Covid”.
17 Mai, 2021 | 09:41hSetting the record straight: There is no ‘Covid heart’ – STAT
Comentário no Twitter
Why the issue of Covid-19 induced cardiac problems was massively overblown and why screening low-risk patients with MRI and other fancy tests is neither necessary nor wise. https://t.co/HkJFOJ6oeM
— Raffaele Rasoini (@RasoiniR) May 14, 2021
“Ainda não acabou”: Proteção incerta das vacinas contra Covid deixam os pacientes oncológicos em um limbo.
17 Mai, 2021 | 09:40h‘It’s not over yet’: Uncertain protection from Covid vaccines leaves cancer patients in limbo – STAT
Relacionado: COVID-19 Vaccines in Patients With Cancer—A Welcome Addition, but There Is Need for Optimization – JAMA Oncology
Crise de COVID-19 na Índia: um chamado para a ação internacional.
17 Mai, 2021 | 09:35hIndia’s COVID-19 crisis: a call for international action – The Lancet
Comentário no Twitter (fio – clique para saber mais)
The team @IndiaCOVIDSOS and others call for international action for India’s COVID-19 crisis in their Lancet paper.https://t.co/T7RvexuMJP@paimadhu @PrakashLab @KrutikaKuppalli @BhramarBioStat @spkalantri @cspramesh pic.twitter.com/QkuYv2QEb6
— Raj Kumar Manna (@rajphys) May 14, 2021
O aumento da pandemia no país ameaça a oferta de um fabricante de vacina indiano para proteger o mundo.
17 Mai, 2021 | 09:34hWHO: É urgente que as nações ricas atrasem a vacinação contra Covid em jovens e doem as vacinas num esquema de solidariedade.
17 Mai, 2021 | 09:32hComentários: Vaccinate vulnerable global poor before children in rich countries, WHO says – The Guardian E Covid: Delay child vaccinations and share jabs with Covax, says WHO – BBC
Relacionado: Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”.