Arquivos do dia: Maio 6, 2021
Em ação surpreendente, EUA se posiciona a favor da liberação de patentes das vacinas contra COVID. “A administração Biden atrai aplausos dos pesquisadores em saúde pública e irrita a indústria farmacêutica.”
6 Mai, 2021 | 07:49hIn shock move, US backs waiving patents on COVID vaccines – Nature
Ver também: U.S. will back proposal to waive intellectual property rights and boost Covid-19 vaccine production – STAT E Statement from the Executive Director of UNAIDS, Winnie Byanyima on the decision by the United States of America to support the TRIPS waiver for COVID-19 vaccines – UNAIDS E WHO Director-General commends United States decision to support temporary waiver on intellectual property rights for COVID-19 vaccines – World Health Organization
Comentário no Twitter
These extraordinary times and circumstances of call for extraordinary measures.
The US supports the waiver of IP protections on COVID-19 vaccines to help end the pandemic and we’ll actively participate in @WTO negotiations to make that happen. pic.twitter.com/96ERlboZS8
— Ambassador Katherine Tai (@AmbassadorTai) May 5, 2021
Estudo randomizado: Vacina Novavax é 49,4% eficaz contra a variante B.1.351 do SARS-CoV-2.
6 Mai, 2021 | 07:46hEstudo observacional no Catar: Vacina da Pfizer–BioNTech se mostrou 89,5% eficaz contra a variante B.1.1.7 e 75% eficaz contra a variante B.1.351. A eficácia da vacina contra doença grave, crítica ou fatal com qualquer variante do SARS-CoV-2 foi de 97,4%.
6 Mai, 2021 | 07:45h
Comentário no Twitter
📍GET BOTH DOSES! Great variants & #COVID19 vaccine news—Pfizer/BioNTech vaccine had great efficacy of 89.5% vs #B117 🇬🇧 variant & 75% vs #B1351 🇿🇦 variant for infection—but only with 2 doses. The 1 dose efficacy was just ~29% vs #B117 & ~17% vs #B1351. 🧵https://t.co/SprUfggnmh pic.twitter.com/VDWHiLsQLL
— Eric Feigl-Ding (@DrEricDing) May 6, 2021
Estudo observacional em Israel: vacina da Pfizer-BioNTech é 95,3% eficaz contra a infecção por SARS-CoV-2.
6 Mai, 2021 | 07:43hComentários: Expert reaction to Israel nation-wide study looking at Pfizer vaccine effectiveness – Science Media Centre E Covid-19: Two doses of Pfizer vaccine are “highly effective” against infection, hospital admission, and death, study finds – The BMJ
Receptores de transplante de órgãos continuam vulneráveis à Covid-19 mesmo depois da segunda dose da vacina.
6 Mai, 2021 | 07:42hEstudo Original: Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients – JAMA
Estudo de coorte mostra resposta imunológica inadequada à vacina de mRNA do SARS-CoV-2 entre receptores de transplante renal.
6 Mai, 2021 | 07:40h
Comentário no Twitter
The studies of mRNA vax in people with transplants are getting bigger: still the same message. Some protection, but not enough. This time, 308 people with kidney transplants in Israel, BNT-Pfizer vaccine https://t.co/Otvt8F11my
— Hilda Bastian, PhD (@hildabast) May 6, 2021
Perspectiva | Quantas mortes por COVID são aceitáveis em um mundo pós-pandemia? “Mesmo depois das vacinações em massa, algumas internações e mortes por coronavírus serão inevitáveis – mas as opiniões divergem sobre quantas são consideradas demais para se retornar a uma relativa normalidade.”
6 Mai, 2021 | 07:38hHow many COVID deaths are acceptable in a post-pandemic world? – Nature
[Comunicado de Imprensa – ainda não publicado] Moderna anuncia dados iniciais positivos com dose de reforço contra as variantes preocupantes do SARS-CoV-2.
6 Mai, 2021 | 07:36hModerna Announces Positive Initial Booster Data Against SARS-CoV-2 Variants of Concern – Moderna
Comentário: We just got our first evidence that Moderna’s coronavirus booster shot works to fight variants – Insider
Comentário no Twitter
Moderna announces that a single dose of their #COVID19 booster shot provides a strong immunologic response to the variant first identified in South Africa (B.1.351) & Brazil (P.1).
This was also well tolerated.
Press release: https://t.co/q46Wx27BzI pic.twitter.com/16JpxrM4Vq
— Isaac Bogoch (@BogochIsaac) May 5, 2021
Great news
💥Single booster dose of 50 µg of mRNA-1273 or mRNA-1273.351 increased neutralizing titers against SARS-CoV-2 and two variants of concern (B.1.351, P.1)in previously vaccinated clinical trial participants💥 https://t.co/rzhDsgxEDh— Antibiotic Steward🆔🦠Bassam Ghanem (@ABsteward) May 6, 2021
Mudança na prática | Um regime de 4 meses de rifapentina com moxifloxacina não é inferior ao regime padrão de 6 meses no tratamento da tuberculose.
6 Mai, 2021 | 07:34hComentário: Four-month TB treatment matches six-month standard of care – Aidsmap
Estudo randomizado: Dexametasona perioperatória reduz náuseas e vômitos pós-operatórios e não está associada a risco aumentado de infecções, mesmo entre pacientes diabéticos.
6 Mai, 2021 | 07:31hRCT: Dexamethasone and Surgical-Site Infection
Dexamethasone and Surgical-Site Infection – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentário: Dexamethasone treatment safe in surgery – Monash University