Arquivos do dia: Abril 30, 2021
ECR: Ácido tranexâmico na prevenção de perda sanguínea após parto cesariano – Embora o uso de AT tenha resultado em redução na incidência da perda sanguínea estimada, a relevância clínica dos achados foi pequena.
30 Abr, 2021 | 09:17h
Comentários no Twitter
Another typically "positive" trial for TXA.
"the mean between-group difference was approximately 100 ml …. the clinical relevance of this narrow difference is questionable"
– No difference in RBC transfusions.
– 0.4% vs 0.1% VTE at 3 mos.— Ryan Radecki, MD MS (@emlitofnote) April 28, 2021
NEJM-Prevention of Blood Loss after Cesarean Delivery | tranexamic acid ➡️ significantly lower incidence of EBL greater than 1000 ml or RBC transfusion by day 2 than placebo, but did not result in a ⬇️ incidence of hemorrhage-related secondary outcomes https://t.co/ydF5HgHM0N
— Skeptical Scalpel (@Skepticscalpel) April 28, 2021
M-A: Prescrição tardia de antibióticos para infecções do trato respiratório é uma estratégia segura e eficaz para a maioria dos pacientes
30 Abr, 2021 | 09:15hComentário: Delayed Antibiotic Prescribing Safe for Respiratory Tract Infection – HealthDay
Diretriz da AHA: Tratamento da hipertensão grau 1 em adultos com baixo risco em 10 anos para doença cardiovascular – “Faltam estudos clínicos randomizados que avaliem o risco de DCV entre indivíduos com hipertensão grau 1 e baixo risco em 10 anos para doença aterosclerórica vascular”
30 Abr, 2021 | 09:13hComunicado de Imprensa: If slightly high blood pressure doesn’t respond to lifestyle change, medication can help – American Heart Association
Principais Itens a Saber: Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease – American Heart Association
Comentário: The Hypertension Pandemic: Need for a Strategic Evidence-based Response – American Heart Association
Diretriz da AHA: Prevenção da endocardite infecciosa por Streptococcus do grupo viridans – Antibioticoprofilaxia para procedimentos dentais invasivos é indicada somente para pacientes de alto risco com as seguintes condições: prótese cardíaca valvar, endocardite infecciosa prévia, doença cardíaca congênita ou transplante cardíaco prévio.
30 Abr, 2021 | 09:11hComunicado de Imprensa: Good dental health may help prevent heart infection from mouth bacteria – American Heart Association
Principais Itens a Saber: Prevention of Viridans Group Streptococcal Infective Endocarditis – American Heart Association
Slide set: Prevention of Viridans Group Streptococcal Infective Endocarditis
Comentário no Twitter (fio – clique para saber mais)
In 2007, antibiotic prophylaxis to prevent VGS IE was scaled back.
“There was no convincing evidence that VGS IE frequency, morbidity, or mortality has increased since 2007.”
Thanks Drs. @LBaddour1, Daniel DeSimone and Walter Wilsonhttps://t.co/r9It8c3IwA pic.twitter.com/EO3gcKZAzG
— Mayo Clinic Infectious Diseases (@MayoClinicINFD) April 18, 2021
Estudo de coorte: Uso concomitante de drogas-Z (zolpidem, zopiclona, zaleplona) e opioides aumenta sobremaneira o risco de overdose
30 Abr, 2021 | 09:08hThe Risk of Overdose With Concomitant Use of Z-Drugs and Prescription Opioids: A Population-Based Cohort Study – American Journal of Psychiatry (link para o resumo – $ para o texto completo)
Comentário: Co-prescribing Opioids, Z-Drugs May Increase Risk of Overdose – Psychiatric News Alert
Revisão: Evolução e status atual do tratamento multidisciplinar do câncer retal localmente avançado
30 Abr, 2021 | 09:05hFDA afirma que irá banir todos os cigarros mentolados e charutos saborizados
30 Abr, 2021 | 09:04hFDA says it will ban all menthol cigarettes and flavored cigars – STAT
Ver também: FDA Moves To Ban Cigarettes And Flavored Cigars – NPR
Orientações da AHA/ASA: Diagnóstico e tratamento da trombose de seio venoso cerebral associada a trombocitopenia trombótica induzida por vacina – “Nenhum tipo de heparina, em qualquer dose, deve ser administrado.”
30 Abr, 2021 | 09:02hComunicado de Imprensa: Guidance on treatment for rare blood clots and low platelets related to COVID-19 vaccine – American Heart Association
Relacionado: ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia
Estudo com 6.9 milhões de pessoas na Inglaterra mostra que a Covid-19 grave em jovens pode ser explicada, em grande parte, pela obesidade – Com IMC acima de 23 kg/m2, há um aumento linear no risco de Covid-19 grave
30 Abr, 2021 | 08:59hComentários: Severe COVID in young people can mostly be explained by obesity – new study – The Conversation E Obesity studies highlight severe COVID outcomes, even in young adults – CIDRAP E Expert reaction to study looking at a potential link between body weight and risk of severe COVID-19, especially for younger adults – Science Media Centre
Comentário no Twitter (fio – clique para saber mais)
NEW—Study of health records of nearly 7 million people in England found that the risk of worse outcomes from #COVID19 starts rising in people with a BMI above 23kg/m2—considered to be in the healthy range.
Read in @TheLancetEndo: https://t.co/5ibn3yb1xO 1/2 pic.twitter.com/4MwnGq95Sz
— The Lancet (@TheLancet) April 29, 2021
Debate: Deve-se usar máscaras ao ar livre?
30 Abr, 2021 | 08:55hShould masks be worn outdoors? – The BMJ
Comentários: Experts debate on wearing masks outdoors – News Medical E Do masks need to be worn outdoors? – Advanced Science News
Comentário no Twitter (Fio – clique para saber mais)
Who do so many of us go off about outdoor masking?
Because if governments can show its people that it's taking #COVID19 seriously by focusing on outdoor masking while ignoring the living and working conditions driving so many infections, we'll get nowhere.#endpandemictheatre
— Stefan Baral (@sdbaral) April 29, 2021