Vacinas
Relato de caso | Trombose com trombocitopenia após vacina de RNA mensageiro–1273.
29 Jun, 2021 | 09:53hThrombosis With Thrombocytopenia After the Messenger RNA–1273 Vaccine – Annals of Internal Medicine
Vacinas de mRNA contra SARS-CoV-2 induzem respostas persistentes do centro germinativo humano, sugerindo uma imunidade de longa duração.
29 Jun, 2021 | 09:52hSARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses – Nature
Comentários: Immune response to FDA-approved vaccines is strong and potentially long-lasting – News Medical
Relacionado: A long-term perspective on immunity to COVID – “Clinical studies now indicate that immunity will be long-lasting”.
Comentário no Twitter (fio – clique para saber mais)
Just published @nature
A bonus factor after covid vaccination: germinal center factories for durable, antigen-specific, B cells and plasmoblasts induced by mRNA vaccination, as determined by lymph node aspirates from vaccinees https://t.co/5eR0gDSWHq@TheBcellArtist @WUSTLmed pic.twitter.com/C5xPSrh5Gw— Eric Topol (@EricTopol) June 28, 2021
Grupo do CDC afirma que ainda não há evidência sugerindo a necessidade de reforço da vacina contra Covid.
25 Jun, 2021 | 10:43hNo evidence yet to suggest Covid vaccine booster is needed, CDC group says – NBC News
Opinião relacionada: 7 Reasons Why We Should Not Need Boosters for COVID-19 – by Monica Ghandi, MD
Perspectiva | As vacinas chinesas contra COVID têm desempenho inferior? A escassez de estudos de vida real deixa questões sem respostas.
25 Jun, 2021 | 10:42hRelacionados: WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. E Brazilian town experiment shows mass vaccination can wipe out COVID-19.
Opinião | As vacinas de mRNA são extraordinárias, mas a Novavax é ainda melhor.
25 Jun, 2021 | 10:41hThe mRNA Vaccines Are Extraordinary, but Novavax Is Even Better – The Atlantic
Comentário no Twitter
The tale of mRNA vaxes & new technology hype, & underestimating the importance of Novavax – a more old-school vaccine with efficacy just as high, & lower adverse events. My latest in @TheAtlantic https://t.co/Hid29G5mkC
— Hilda Bastian, PhD (@hildabast) June 24, 2021
Painel consultivo do CDC apoia o uso da vacina contra dengue em áreas de alto risco, apesar dos desafios na distribuição.
25 Jun, 2021 | 10:33hMais um estudo mostra que uma dose única de vacina de mRNA tem efeito máximo em pacientes com infecção prévia.
24 Jun, 2021 | 11:07hPrimary, Recall, and Decay Kinetics of SARS-CoV-2 Vaccine Antibody Responses – ACS Nano
Relacionado: France recommends single dose of vaccine if previous Covid infection detected. E [Preprint] More data showing a single-dose SARS-CoV-2 mRNA vaccine may be enough in individuals with previous COVID-19. E Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19
Comentário no Twitter
Prior covid? Unless it's a severe case, one-dose mRNA vaccine adds considerable protection and nothing added by 2nd dose. This is now concordant w/ >20 studieshttps://t.co/8Qpuw193zk @acsnano pic.twitter.com/TJNbl8HPy9
— Eric Topol (@EricTopol) June 23, 2021
3 doses de vacina de mRNA contra Covid-19 em receptores de transplante de órgão sólido pode melhorar a imunogenicidade da vacina.
24 Jun, 2021 | 11:05hEfeitos da vacinação na transmissão domiciliar do SARS-CoV-2 na Inglaterra – “A probabilidade de transmissão domiciliar foi de aproximadamente 40 a 50% menor em familiares de pacientes-índice vacinados 21 dias ou mais antes do teste positivo do que os familiares de pacientes-índice não vacinados.”
24 Jun, 2021 | 11:04hRelacionados: Study in England showed one dose of COVID-19 vaccine can cut household transmission by up to half – This protection is on top of the reduced risk of a vaccinated person developing symptomatic infection, which is around 60 to 65% after the first dose E Covid-19 vaccination prevents transmission from vaccinated to unvaccinated household members.
CDC | Vacinas de mRNA parecem ter ligação com casos de miocardite e pericardite – 1.226 casos de miocardite ou pericardite foram relatados, a maioria em pessoas com menos de 30 anos de idade.
24 Jun, 2021 | 11:00hVer também: Experts: mRNA COVID-19 vaccines likely tied to heart inflammation – CIDRAP
Relacionados: Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination. E Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination. E Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination. E CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. E Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. E CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.