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Vacinas

Estudo do CDC | Vacina contra COVID-19 está associada com proteção 5 vezes maior que a “imunidade natural”.

1 Nov, 2021 | 10:59h

Laboratory-Confirmed COVID-19 Among Adults Hospitalized with COVID-19–Like Illness with Infection-Induced or mRNA Vaccine-Induced SARS-CoV-2 Immunity — Nine States, January–September 2021 – CDC Morbidity and Mortality Weekly Report

Comentários:

COVID-19 vaccine gives 5 times the protection of ‘natural immunity,’ data show – CIDRAP

COVID shots more protective than past infection, study shows – Associated Press

 

Comentário no Twitter

 

Opinião | A vacina da Moderna é realmente melhor que a da Pfizer – ou é somente uma dose maior?

1 Nov, 2021 | 10:58h

Is Moderna Really Better Than Pfizer—Or Is It Just a Higher Dose? – The Atlantic

Conteúdo relacionado: CDC Report: Moderna’s vaccine associated with greater effectiveness (93%) against Covid-19 hospitalization compared to Pfizer (88%) and J&J (71%) vaccines.

 

Comentário no Twitter

 

A efetividade da vacina da AstraZeneca em idosos durante a circulação da variante gama do SARS-CoV-2 em São Paulo foi de 77,9% contra Covid-19 sintomática, 87,6% contra internação e 93,6% contra morte.

29 Out, 2021 | 14:59h

Effectiveness of ChAdOx1 vaccine in older adults during SARS-CoV-2 Gamma variant circulation in São Paulo – Nature Medicine

 

Comentário no Twitter (fio – clique para saber mais)

 

Vacinas de mRNA induzem memória imunológica durável contra SARS-CoV-2 e variantes de preocupação.

29 Out, 2021 | 14:53h

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern – Science

 

Comentário do autor no Twitter (fio – clique para saber mais)

 

O que as vacinas contra COVID em crianças mais novas podem significar para a pandemia.

28 Out, 2021 | 16:14h

What COVID vaccines for young kids could mean for the pandemic – Nature

Conteúdo relacionado: FDA advisory panel recommends Pfizer Covid-19 vaccine be authorized for children ages 5 to 11.

Painel consultivo do FDA recomenda que a vacina da Pfizer contra a Covid-19 seja autorizada para crianças de 5 a 11 anos de idade.

27 Out, 2021 | 12:44h

FDA advisory panel recommends Pfizer Covid-19 vaccine be authorized for children – STAT

Ver também:

Tracking the FDA advisory panel meeting on Covid-19 vaccines for kids – STAT

FDA advisory panel recommends Pfizer vaccine for kids ages 5 to 11 – NPR

Vacinação heteróloga AstraZeneca/Pfizer parece estar associada com maior efetividade contra Covid-19 em comparação com a vacinação homóloga Pfizer/Pfizer.

27 Out, 2021 | 12:41h

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination – Nature

Conteúdos relacionados:

Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden.

Should You Mix and Match Your Booster Shot?

Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no efficacy data but there was increased antibody production on study days 15 and 29 after booster shots from Moderna and Pfizer.

A primer on what we know about mixing and matching Covid vaccines.

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination.

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

 

Comentário no Twitter

 

Diferentes vacinas contra COVID misturadas e combinadas com sucesso no teste de efetividade – “Não é preciso se restringir a nenhuma marca.”

27 Out, 2021 | 12:39h

Mix-and-match COVID vaccines ace the effectiveness test – Nature

Conteúdos relacionados:

Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden.

Should You Mix and Match Your Booster Shot?

Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no efficacy data but there was increased antibody production on study days 15 and 29 after booster shots from Moderna and Pfizer.

A primer on what we know about mixing and matching Covid vaccines.

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination.

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

[Comunicado de imprensa – ainda não publicado] Moderna afirma que sua vacina contra COVID produz forte resposta imunológica em crianças de 6 a 11 anos.

26 Out, 2021 | 11:36h

Comunicado de imprensa: Moderna Announces Positive Top Line Data from Phase 2/3 Study of COVID-19 Vaccine in Children 6 to 11 Years of Age

Comentário: Moderna says new data supports its COVID vaccine for kids 6 to 11 – NPR

O que significa estar totalmente vacinado.

26 Out, 2021 | 11:28h

What It Means To Be Fully Vaccinated – Think Global Health

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