Vacinas

Estudo randomizado | Análise final de eficácia e segurança da vacina de dose única da J&J.

10 Fev, 2022 | 13:53h

Final Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S – New England Journal of Medicine

 

Comentário no Twitter

A single injection of the Ad26.COV2.S Covid-19 vaccine showed 56.3% vaccine efficacy beginning 14 days after injection and 52.9% efficacy more than 28 days after injection against moderate to severe–critical #COVID19. #IDTwitter https://t.co/0VhaEUtmwq pic.twitter.com/04QqSyYwNI

— NEJM (@NEJM) February 9, 2022

 

---

[Preprint] Vigilância ativa de miocardite e pericardite decorrentes da vacinação contra COVID-19 com vacinas do tipo mRNA em pessoas de 12-39 anos na Itália.

10 Fev, 2022 | 13:13h

Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy: a multi-database, self-controlled case series study -medRxiv

Conteúdos relacionados:

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

Comentário no Twitter

The incidence of mRNA vaccine myocarditis or pericarditis in Italy in ~3 million vaccinees age 12-39. Excess cases per 100,000; orange is 2nd dose, blue 1st dose. https://t.co/xvdV4qSdHw
Pfizer:~1/100,000 age 12-39, all 2nd dose
Moderna,: >5/100,000, age 12-39, and some 1st dose pic.twitter.com/Y1jfGrU53v

— Eric Topol (@EricTopol) February 9, 2022

 

---

Revisão sistemática | Eficácia clínica e imunológica das vacinas contra COVID-19 em populações imunocomprometidas.

10 Fev, 2022 | 13:08h

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review – Clinical Microbiology and Infection

---

Perspectiva | Três, quatro ou mais: qual é o “número mágico” de doses de reforço?

8 Fev, 2022 | 14:53h

Three, four or more: what’s the magic number for booster shots? – Nature

---

Primeiros pacientes vacinados contra HIV, em estudo clínico, com a vacina experimental da Moderna que usa tecnologia de mRNA.

4 Fev, 2022 | 17:06h

First patients vaccinated in clinical trial of HIV experimental vaccine that uses Moderna’s mRNA technology – CNN

---

10 bilhões de doses de vacinas contra COVID: mundo atinge nova marca.

4 Fev, 2022 | 16:05h

Ten billion COVID vaccinations: world hits new milestone – Nature

 

Comentário no Twitter

10 billion doses given, <1 billion were boosters
1 continent nearly left outhttps://t.co/DrCqQ4b7tJ
and @OurWorldInData

“It is a huge scientific achievement that ten billion doses of vaccines to a new pathogen were developed in two years from its identification”—@doctorsoumya pic.twitter.com/pyLXlvI22Q

— Eric Topol (@EricTopol) February 1, 2022

 

---

Editorial | Menstruação e vacinação contra Covid-19.

4 Fev, 2022 | 16:02h

Menstruation and covid-19 vaccination – The BMJ

Comunicado de imprensa: New studies provide reassuring data on menstrual changes after covid-19 vaccination – BMJ

 

Comentário no Twitter

The findings from two new studies are reassuring: "changes to the menstrual cycle do occur following vaccination, but they are small compared with natural variation and quickly reverse"https://t.co/QFZ4I1U6yd

— The BMJ (@bmj_latest) January 28, 2022

 

---

Breve revisão | Reações de hipersensibilidade a vacinas em crianças: do sarampo ao SARS-CoV-2.

4 Fev, 2022 | 15:34h

Hypersensitivity reactions to vaccines in children: from measles to SARS-CoV-2 – Pediatric Allergy and Immunology

Comentário: Vaccine hypersensitivity in children – News Medical

---

O mundo precisa de uma vacina contra a Ômicron? O que dizem os pesquisadores.

4 Fev, 2022 | 15:05h

Does the world need an Omicron vaccine? What researchers say – Nature

---

O sucesso extraordinário das vacinas contra Covid-19, em 2 gráficos.

4 Fev, 2022 | 15:03h

The extraordinary success of Covid-19 vaccines, in two charts – Vox

---