Tumores Gastrintestinais
Estudo de coorte | Associação da remoção incompleta de pólipo em colonoscopia com risco de câncer colorretal no seguimento.
17 Ago, 2021 | 11:17hEstudo original: Recurrence of Colorectal Neoplastic Polyps After Incomplete Resection – Annals of Internal Medicine (link para o resumo – $ para o texto completo)
Incidência e mortalidade globais do câncer gástrico, 1980-2018.
13 Ago, 2021 | 11:55hGlobal Incidence and Mortality of Gastric Cancer, 1980-2018 – JAMA Network Open
Lesões císticas pancreáticas: achados de imagem de RM e tratamento.
11 Ago, 2021 | 10:28hCystic pancreatic lesions: MR imaging findings and management – Insights into Imaging
Conteúdos relacionados:
Recommendations for the management of incidental pancreatic findings in adults.
Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management
Management of Pancreatic Cystic Lesions
Consensus Recommendations: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions
Review: Pancreatic Cystic Lesions
Guidelines on pancreatic cystic neoplasms
Estudo randomizado | Eficácia da quimioterapia concomitante com S-1 vs. radioterapia isolada para pacientes idosos com câncer esofágico.
9 Ago, 2021 | 11:14hEfficacy of Concurrent Chemoradiotherapy With S-1 vs Radiotherapy Alone for Older Patients With Esophageal Cancer: A Multicenter Randomized Phase 3 Clinical Trial – JAMA Oncology (gratuito por tempo limitado)
Editorial: Primary Chemoradiotherapy for Older Patients With Esophageal Cancer (gratuito por tempo limitado)
Comentário: Concurrent CRT Effective for Esophageal Cancer in Older Patients — Overall survival at 2 years significantly better versus radiotherapy alone – MedPage Today (necessário cadastro gratuito)
Comentário no Twitter
Randomized phase 3 trial of radiation with or w/o S-1 chemo in 298 older pts (median age 77) with esophageal cancer reveals concurrent chemoradiation led to significantly improved progression-free & overall survival https://t.co/wx5FG5VDUH #GICSM pic.twitter.com/SFddL53lCi
— JAMA Oncology (@JAMAOnc) August 6, 2021
Recomendações de consenso internacional sobre as principais medidas de desfecho para preservação de órgão após (químio)radioterapia em paciente com câncer retal.
5 Ago, 2021 | 11:34hEstudo randomizado | Nivolumabe com quimioterapia vs. quimioterapia isolada para adenocarcinomas esofágico, de junção gastresofágica e gástrico avançados.
3 Ago, 2021 | 11:09hFirst-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)
Comentário no Twitter (fio – clique para sair mais)
#Nivolumab plus chemotherapy shows superior OS, PFS benefit, and acceptable safety profile—compared to chemotherapy alone—in previously untreated advanced gastric, gastro-oesophageal junction, or oesophageal adenocarcinoma.
🔗 https://t.co/0u9R5ZIwd2, by @YJanjigianMD et al.
— The Lancet (@TheLancet) July 8, 2021
Estudo randomizado | Sintilimabe com bevacizumabe biossimilar vs. sorafenibe no carcinoma hepatocelular irressecável.
22 Jul, 2021 | 12:59hSintilimab plus a bevacizumab biosimilar (IBI305) versus sorafenib in unresectable hepatocellular carcinoma (ORIENT-32): a randomised, open-label, phase 2–3 study – The Lancet Oncology (link para o resumo – $ para o texto completo)
Comentário no Twitter
In a phase III trial involving 571 pts with unresectable HCC, the anti-PD-1 mAb sintilimab + the bevacizumab biosimilar IBI305 improved PFS (median 4.6 vs 2.8 months with sorafenib; HR 0.56, P <0.0001) & OS (median NR vs 10.4 months; HR 0.57, P <0.0001), https://t.co/UF43FGdMMy
— NatureRevClinOncol (@NatRevClinOncol) June 22, 2021
Atualização da Diretriz de Prática Clínica da AGA para quimioprevenção do câncer colorretal.
16 Jul, 2021 | 09:47h
Comentário no Twitter
Out now in @AGA_CGH: AGA Clinical Practice Update on Chemoprevention for Colorectal Neoplasia. Had great time working on this with @AasmaShaukatMD & @seth_crockett. Hope it's a useful reference! @AmerGastroAssn
https://t.co/UB5hFMq6hc pic.twitter.com/KwHeKjU2dk— Peter Liang, MD MPH (@petersliang) February 19, 2021
Impacto global do câncer atribuído ao consumo de álcool – “Em termos globais, estima-se que 741.300 casos, ou 4,1% de todos os novos casos de câncer em 2020, foram atribuídos ao consumo de álcool.”
14 Jul, 2021 | 11:36hComunicado de imprensa: Alcohol consumption linked to more than 740,000 new cancer cases in 2020 – The Lancet
Comentários: Alcohol caused 740,000 cancer cases globally last year – study – The Guardian E Expert reaction to study of alcohol and cancer – Science Media Centre
Estudo randomizado | Eficácia de longo prazo da quimiorradioterapia neoadjuvante somada à cirurgia para o tratamento de carcinoma esofágico de células escamosas localmente avançado.
13 Jul, 2021 | 11:09h
Comentário no Twitter
Long-term outcomes from the NEOCRTEC5010 demonstrated the survival benefit of neoadjuvant chemoradiotherapy followed by surgery compared with surgery alone for patients with locally advanced esophageal squamous cell carcinoma https://t.co/UBBEEAynsy
— JAMA Surgery (@JAMASurgery) June 29, 2021