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M-A | Prevalência de infecção oculta pelo vírus da hepatite B em adultos.

16 Ago, 2022 | 12:43h

Prevalence of occult hepatitis B virus infection in adults: a systematic review and meta-analysis – The Lancet Gastroenterology & Hepatology

Comentário no Twitter

New Article online — a systematic review and meta-analysis of the prevalence of occult #HBV infection in adults — FREE to read https://t.co/oaa1HHfQo0 @dryuriim @leithdamien @chipsliverlover @GeYueqi @gndow @maud_lemoine #LiverTwitter #IDtwitter #viralhepatitis #hepatitisB pic.twitter.com/liMf9CBAzK

— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) August 10, 2022

Implementação de recomendações nas doenças reumáticas e musculoesqueléticas: considerações para desenvolvimento e atualização.

16 Ago, 2022 | 12:42h

Implementation of recommendations in rheumatic and musculoskeletal diseases: considerations for development and uptake – Annals of Rheumatic Diseases

Estudo randomizado | Segurança e imunogenicidade da vacina tifoide conjugada em crianças de 9 meses a 12 anos de idade no Malawi.

16 Ago, 2022 | 12:41h

Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi: a nested substudy of a double-blind, randomised controlled trial – The Lancet Global Health

Comentários:

Typhoid conjugate vaccine: are we heading towards the elimination of typhoid in endemic countries? – The Lancet Global Health

New TCV data from Malawi highlight longer-term immune response – Coalition Against Typhoid

Conteúdos relacionados:

Safety and Efficacy of a Typhoid Conjugate Vaccine in Malawian Children – New England Journal of Medicine

Cluster RCT: Vaccination of children against typhoid fever with a Vi-tetanus toxoid conjugate vaccine in urban Bangladesh conferred 85% total protection.

Randomized Trial: Efficacy Analysis of a Typhoid Conjugate Vaccine

Revisão | Hipotensão perioperatória: causas e soluções.

16 Ago, 2022 | 12:40h

Perioperative hypotension: causes and remedies – Journal of Anesthesia, Analgesia and Critical Care

M-A | Intervenções para reduzir infecções em pacientes com malignidades hematológicas.

16 Ago, 2022 | 12:39h

Interventions to reduce infections in patients with hematological malignancies: a systematic review and meta-analysis – Blood Advances

Comentário: Prophylactic Immunoglobulin, Vaccinations May Reduce Infections in Hematologic Malignancies – AJMC

M-A de estudos randomizados | Ácido tranexâmico profilático na redução de perda sanguínea e morbidades relacionadas durante a histerectomia.

16 Ago, 2022 | 12:38h

Prophylactic tranexamic acid to reduce blood loss and related morbidities during hysterectomy: a systematic review and meta-analysis of randomized controlled trials – Obstetrics & Gynecology Science (PDF)

Estudo de coorte | Análise de características clínicas, testes diagnósticos e biomarcadores em pacientes com suspeita de doença de Creutzfeldt-Jakob.

16 Ago, 2022 | 12:37h

Analysis of Clinical Features, Diagnostic Tests, and Biomarkers in Patients With Suspected Creutzfeldt-Jakob Disease, 2014-2021 – JAMA Network Open

Comentário no Twitter

In patients with suspected Creutzfeldt-Jakob disease, CSF RT-QuIC, CSF T-tau, and stereotyped MRI anomalies were associated with diagnosis; myoclonus, stereotyped EEG anomalies, and CSF protein 14-3-3 were less helpful. #CohortStudy https://t.co/w3iaHMj3co

— JAMA Network Open (@JAMANetworkOpen) August 3, 2022

Resultados de longo prazo de estudo randomizado fase 2 | Elotuzumabe com pomalidomida e dexametasona para mieloma múltiplo recidivante/refratário.

16 Ago, 2022 | 12:35h

Elotuzumab Plus Pomalidomide and Dexamethasone for Relapsed/Refractory Multiple Myeloma: Final Overall Survival Analysis From the Randomized Phase II ELOQUENT-3 Trial – Journal of Clinical Oncology

Estudo original: Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma – New England Journal of Medicine

Resultados de longo prazo de estudo randomizado | Gefitinibe isolado vs. gefitinibe com quimioterapia para câncer de pulmão de não pequenas células com mutação no EGFR.

16 Ago, 2022 | 12:34h

Updated Analysis of NEJ009: Gefitinib-Alone Versus Gefitinib Plus Chemotherapy for Non–Small-Cell Lung Cancer With Mutated EGFR – Journal of Clinical Oncology

Estudo original: Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non–Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study – Journal of Clinical Oncology

Estudo randomizado fase 2 | Inibição de Poli-ADP-ribose polimerase de manutenção selecionada por biomarcador com rucaparibe após quimioterapia para carcinoma urotelial metastático.

16 Ago, 2022 | 12:33h

A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition With Rucaparib Following Chemotherapy for Metastatic Urothelial Carcinoma – Journal of Clinical Oncology