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Estudo randomizado fase 1/2 | Segurança e eficácia do inibidor mTOR (vistusertibe) combinado com anastrazol em pacientes com câncer endometrial metastático ou positivo para receptor hormonal.
27 Mai, 2022 | 13:22hSafety and Efficacy of the mTOR Inhibitor, Vistusertib, Combined With Anastrozole in Patients With Hormone Receptor−Positive Recurrent or Metastatic Endometrial Cancer: The VICTORIA Multicenter, Open-label, Phase 1/2 Randomized Clinical Trial – JAMA Oncology (link para o resumo – $ para o texto completo)
Comentário no Twitter
Endocrine therapy is used in clinical practice in the management of relapsed or advanced HR + endometrial cancer. Anastrozole + vistusertib demonstrated clinically significant improvement with manageable adverse events, encouraging further research https://t.co/hHDtloSdNs #GynCSM
— JAMA Oncology (@JAMAOnc) May 12, 2022
Revisão sistemática | Curativos e agentes tópicos para tratamento de feridas abertas após tratamento cirúrgico de cisto pilonidal sacrococcígeo.
27 Mai, 2022 | 13:21h
Comentário no Twitter
How effective are dressings and topical agents in the management of wounds after surgical treatment for pilonidal sinus of the buttocks?
Our new review brings together evidence from 11 studies with a total of 932 participants:https://t.co/eLAnnQXoEv#PilonidalSinus #Wounds— Cochrane Wounds (@CochraneWounds) May 23, 2022
Revisão sistemática | Tratamento para sialorreia em pessoas com esclerose lateral amiotrófica/doença do neurônio motor.
27 Mai, 2022 | 13:20hResumo: Treatment of unintentional drooling of saliva in motor neuron disease – Cochrane Library
M-A | Efetividade e prejuízos do aconselhamento contraceptivo e intervenções para provê-lo a mulheres.
27 Mai, 2022 | 13:18hEffectiveness and Harms of Contraceptive Counseling and Provision Interventions for Women: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link para o resumo – $ para o texto completo)
Resumo em vídeo: Effectiveness and Harms of Contraceptive Counseling and Provision Interventions for Women: A Systematic Review and Meta-analysis
Comentário: Contraceptive counseling, provision increases use, reduces unintended pregnancy – ACP Internist
Revisão | Função da diálise peritoneal em diferentes fases do transplante renal.
27 Mai, 2022 | 13:17hThe Role of Peritoneal Dialysis in Different Phases of Kidney Transplantation – Kidney360
Diretriz prática para pesquisa qualitativa | Parte 6 – Abordagens qualitativas longitudinais e de métodos misturados para temas de saúde complexos e longitudinais em pesquisas de atenção primária.
27 Mai, 2022 | 13:16hOutros artigos da série:
Series: Practical guidance to qualitative research. Part 1: Introduction
Series: Practical guidance to qualitative research. Part 2: Context, research questions and designs
Series: Practical guidance to qualitative research. Part 3: Sampling, data collection and analysis
Series: Practical guidance to qualitative research. Part 4: Trustworthiness and publishing
Diretriz de consenso Delphi | Efeitos adversos e segurança em pacientes com glaucoma – Agreement on Clinical Trial Outcomes for Reports on Eye Drops (ASGARD).
27 Mai, 2022 | 13:14hM-A | Tratamento do diabetes tipo 2 com tirzepatida, um agonista duplo do receptor de GIP/GLP-1.
27 Mai, 2022 | 13:13hConteúdos relacionados:
Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis – Nature Medicine
Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial – JAMA (link para o resumo – $ para o texto completo)
Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)
Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)
Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)
Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Estudo randomizado | Aumolertinibe vs. gefitinibe como terapia de primeira linha para câncer de pulmão de não pequenas células localmente avançado ou metastático com deleção do EGFR Exon 19 ou mutações L858R.
27 Mai, 2022 | 13:10h
Comentário no Twitter
Aumolertinib (a 3rd gen TKI) is effective in the first-line treatment of EGFR-mutant NSCLC-AENEAShttps://t.co/QL6xXptxFa pic.twitter.com/grIbapsxzU
— K Pavithran (@drkpavithran) May 18, 2022
Sob licença de: https://creativecommons.org/licenses/by-nc-nd/4.0/
Revisão | Mudança climática e risco de doenças infecciosas.
27 Mai, 2022 | 13:08hClimate Change and Cascading Risks from Infectious Disease – Infectious Diseases and Therapy
Comentário no Twitter
Climate change is adversely affecting the burden of infectious disease throughout the world, which is a health security threat
Fantastic 🆕💥💥Review @InfectDis_Ther
Climate Change and Cascading Risks from Infectious Disease #IDTwitter #MedEd #TwitteRx https://t.co/eU85fOZzN0 pic.twitter.com/T6VKXe1dCP— Antibiotic Steward Bassam Ghanem🆔🔥 (@ABsteward) May 20, 2022
Sob licença de http://creativecommons.org/licenses/by-nc/4.0/