Todos os posts

Diretrizes de consenso sobre diagnóstico e tratamento de apneia obstrutiva do sono em pacientes com doença cardiovascular.

11 Jul, 2022 | 13:51h

Asian Pacific Society of Cardiology Consensus Statements on the Diagnosis and Management of Obstructive Sleep Apnoea in Patients with Cardiovascular Disease – European Cardiovascular Review

 

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Estudo de coorte | Taxas de eventos adversos graves e reoperação após cirurgia artroscópica de ombro.

11 Jul, 2022 | 13:50h

Serious adverse event rates and reoperation after arthroscopic shoulder surgery: population based cohort study – The BMJ

Comunicado de imprensa: Overall risks of shoulder surgery low, but study finds significant risk of reoperation – BMJ Newsroom

 

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Estudo randomizado | Neuromodulação sacral para disfunção neurogênica do trato urinário inferior.

11 Jul, 2022 | 13:49h

Sacral Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction – NEJM Evidence

 

Comentário no Twitter

Pts with neurogenic lower urinary tract dysfunction had sacral neuromodulators implanted and optimized. They were then randomized to have the device either remain ON or switched OFF for 2 months. The success rate was 76% in the ON group vs 42% in the OFF. https://t.co/dhteW70jXp pic.twitter.com/1c0w8HOMJm

— NEJM Evidence (@NEJMEvidence) July 7, 2022

 

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Estudo randomizado | Efeito da eletroacupuntura sobra a insônia em pacientes com depressão.

11 Jul, 2022 | 13:48h

Effect of Electroacupuncture on Insomnia in Patients With Depression: A Randomized Clinical Trial – JAMA Network Open

Comentário convidado: Effects of Electroacupuncture for Depression-Related Insomnia – JAMA Network Open

 

Comentário no Twitter

This randomized clinical trial found that an 8-weeek electroacupuncture with standard care improved sleep quality for patients with insomnia and depression, compared with sham acupuncture and/or standard care. https://t.co/nacnxEI4Ik

— JAMA Network Open (@JAMANetworkOpen) July 7, 2022

 

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Estudo transversal | Comparação da exposição à radiação entre ecocardiografistas intervencionistas, cardiologistas intervencionistas e ultrassonografistas durante intervenções cardíacas estruturais percutâneas.

11 Jul, 2022 | 13:46h

Comparison of Radiation Exposure Among Interventional Echocardiographers, Interventional Cardiologists, and Sonographers During Percutaneous Structural Heart Interventions – JAMA Network Open

 

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Estudo randomizado | Cabozantinibe com atezolizumabe vs. sorafenibe para carcinoma hepatocelular avançado.

11 Jul, 2022 | 13:45h

Cabozantinib plus atezolizumab versus sorafenib for advanced hepatocellular carcinoma (COSMIC-312): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology

Comentário convidado: Cabozantinib plus atezolizumab in advanced hepatocellular carcinoma and the role of adjuvant antiviral therapy – The Lancet Oncology (necessário cadastro gratuito)

 

Comentário no Twitter

In the phase III COSMIC-312 trial in 837 pts with advanced-stage HCC, mPFS was 6.8 vs 4.2 months (HR 0.63; P=.0012) & mOS was 15.4 vs 15.5 months (HR 0.90; P=.44) with cabozantinib+atezolizumab vs sorafenib; mPFS with cabozantinib alone was 5.8 months: https://t.co/eiZEqSxLAr

— NatureRevClinOncol (@NatRevClinOncol) July 6, 2022

 

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Estudo randomizado | Ustequinumabe não melhora os desfechos de pacientes com lúpus eritematoso sistêmico.

11 Jul, 2022 | 13:44h

Phase 3, multicentre, randomised, placebo-controlled study evaluating the efficacy and safety of ustekinumab in patients with systemic lupus erythematosus – Annals of Rheumatic Diseases

 

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Estudo randomizado | Balovaptam não é melhor que placebo para a comunicação social no transtorno do espectro autista infantil.

11 Jul, 2022 | 13:43h

Balovaptan vs Placebo for Social Communication in Childhood Autism Spectrum Disorder: A Randomized Clinical Trial – JAMA Psychiatry

 

Comentário no Twitter

In this RCT, balovaptan did not demonstrate efficacy in improvement of socialization and communication in pediatric autism spectrum disorder (ASD), highlighting challenges faced in #ASD trial design, such as outcome measure sensitivity & placebo response. https://t.co/FFAJeu5xv0

— JAMA Psychiatry (@JAMAPsych) July 6, 2022

 

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M-A | Terapia medicamentosa antitireoidiana na gestação e risco de anomalias congênitas.

11 Jul, 2022 | 13:42h

Antithyroid drug therapy in pregnancy and risk of congenital anomalies: Systematic review and meta-analysis – Clinical Endocrinology

 

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Podcast | Dicas de BRUE: entendendo a apresentação de eventos inexplicados e resolvidos em crianças.

11 Jul, 2022 | 13:40h

#54: BRUE’s Clues: Understanding Brief Resolved Unexplained Events with Dr. Tieder – The Cribsiders

 

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