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Estudo randomizado | Teste farmacogenômico para interações medicamento-genes fornece pouco benefício à remissão de sintomas no transtorno depressivo maior.
18 Jul, 2022 | 13:04hEffect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial – JAMA (gratuito por tempo limitado)
Editorial: Pharmacogenomic Testing for Next-Step Antidepressant Selection: Still a Work in Progress – JAMA (gratuito por tempo limitado)
Comentário: Does Pharmacogenomic Testing Improve Outcomes in Major Depressive Disorder? — The evidence is unclear – MedPage Today (necessário cadastro gratuito)
Comentário no Twitter
In this randomized clinical trial, pharmacogenomic testing for drug-gene interactions in major depressive disorder reduced prescription of medications with predicted drug-gene interactions but had small and nonpersistent effects on symptom remission. https://t.co/Z2OIK3h1Bo pic.twitter.com/8eKSipfBFN
— JAMA (@JAMA_current) July 12, 2022
FDA autoriza o uso emergencial da vacina Novavax contra COVID-19.
18 Jul, 2022 | 13:01hComentários:
FDA authorizes Novavax Covid vaccine, in hopes the traditional shot will convince holdouts – STAT
US regulators OK new COVID-19 shot option from Novavax – Associated Press
Como se recuperar de um projeto de doutorado malsucedido.
18 Jul, 2022 | 13:00hHow to bounce back from a PhD-project failure – Nature
Série de casos de crianças com hepatite aguda e infecção pelo adenovírus humano.
18 Jul, 2022 | 12:59hA Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Estudo relacionado: Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentário: Unexplained Acute Hepatitis in Children: More Evidence for Adenovirus 41 — Two studies point to a suspiciously high prevalence – MedPage Today (necessário cadastro gratuito)
Comentários no Twitter
A majority of children admitted to a single hospital in late 2021–early 2022 with acute hepatitis of unknown cause tested positive for adenovirus. This report describes the children’s illnesses and outcomes. https://t.co/QYvi6U1jUN pic.twitter.com/auPRq1duQm
— NEJM (@NEJM) July 13, 2022
From January–April 2022, 44 children with acute hepatitis of unknown cause were referred to a liver-transplantation center in the U.K. Six underwent liver transplantation. https://t.co/CMI4KCqdxM pic.twitter.com/og72u58L5R
— NEJM (@NEJM) July 13, 2022
Relatório OMS atualizado | Hepatite aguda grave de origem desconhecida em crianças.
18 Jul, 2022 | 12:56hSevere acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Conteúdos relacionados:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (se o acesso a este link for pago, tente este)
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (se o acesso a este link for pago, tente este)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Estudo de coorte de abrangência nacional | Segurança dos esquemas de vacinação primária heteróloga e reforços com vacinas ChAdOx1-S e BNT162b2 ou mRNA-1273.
18 Jul, 2022 | 12:54h
M-A de estudos randomizados | Acetato de megestrol não é benéfico para a anorexia/caquexia relacionada ao câncer.
18 Jul, 2022 | 12:53h
Sistema de relatório Coronary Artery Disease Reporting and Data System (CAD-RADS 2.0) para pacientes submetidos a angiotomografia coronariana.
18 Jul, 2022 | 12:52hComentário: SCCT Releases New Expert Consensus Document on CAD Reporting – American College of Cardiology
Diretriz de consenso | Indicações clínicas e triagem para ecocardiografia transtorácica em adultos.
18 Jul, 2022 | 12:51h
Diretrizes de enfermagem da EBMT sobre a terapia CAR-T | Estrutura para o cuidado do paciente e tratamento das toxicidades comuns.
18 Jul, 2022 | 12:50h