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M-A | Repetição de ressecção hepática vs. ablação percutânea para tratamento de carcinoma hepatocelular recorrente.

5 Ago, 2022 | 17:03h

Repeat hepatic resection versus percutaneous ablation for the treatment of recurrent hepatocellular carcinoma: meta-analysis – BJS Open

Comentário no Twitter

Recurrent #HCC after resection: re-resect or ablate?
📰#systematicreview

Redo-Resection has:
– ⏫Morbidity 17% vs 3%
– ⏫ recurrence free survival (HR 0.79)
– ⚖️ overall survival (HR 0.93 (0.83-1.04))https://t.co/WWwsHNkNQ9 #SoMe4Surgery #some4hpb @SEIQuirurgica @asgbi pic.twitter.com/h4apdpY7eh

— BJS Open (@BjsOpen) May 6, 2022

Estudo randomizado | Fundoplicatura posterior total vs. parcial no reparo cirúrgico de hérnias paraesofágicas.

5 Ago, 2022 | 17:01h

Total versus partial posterior fundoplication in the surgical repair of para-oesophageal hernias: randomized clinical trial – BJS Open

Comentário no Twitter

Does wrap type affect #dysphagia #qol and #recurrence in paraoesophageal #hernia repair?#RCT n=70 Nissen vs Toupet
Partial wrap (Toupet) assoc w/reduced dysphagia, better qol. No diff recurrence rate.#some4surgery #surgicalresearch #some4ugi https://t.co/8tIvryfqYJ pic.twitter.com/47AT1lLPH8

— BJS Open (@BjsOpen) May 9, 2022

Cânceres mucinosos retais: características clínicas e prognóstico em uma coorte de base populacional.

5 Ago, 2022 | 17:00h

Mucinous rectal cancers: clinical features and prognosis in a population-based cohort – BJS Open

Comentário no Twitter

Colleagues from 🇸🇪 present data on 263 mucinous #rectalcancer
-53% stage III/28% stage IV
-5 yr OS 55%
-pCR achieved in 13%, downstaging also commonly achieved with neoadj CRT.

Interesting read!https://t.co/mKCz4vjWHm #Some4surgery #Colorectalsurgery pic.twitter.com/Yc1yHAwyvN

— BJS Open (@BjsOpen) May 4, 2022

Diretriz | Prevenção da obesidade em mulheres de meia-idade.

5 Ago, 2022 | 16:51h

Preventing Obesity in Midlife Women: A Recommendation From the Women’s Preventive Services Initiative – Annals of Internal Medicine

Comunicado de imprensa: Women’s Preventive Services Initiative issues guidelines for preventing obesity in midlife women – American College of Physicians

Comentário: Counseling Can Prevent Obesity in Normal, Overweight Women – HealthDay

Comentário no Twitter

New guidelines aim to prevent #obesity in midlife women. @TheWPSI recommends counseling to prevent weight gain in all women at normal or overweight BMI. Full text available at https://t.co/P8VwBWIHXe @CedarsSinai @acog pic.twitter.com/YxTQVgXj59

— Annals of Int Med (@AnnalsofIM) August 2, 2022

Estudo RECOVERY | Baricitinibe em pacientes hospitalizados com COVID-19.

5 Ago, 2022 | 16:50h

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis – The Lancet

Comentário convidado: Baricitinib in COVID-19: a coming-of-age from artificial intelligence to reducing mortality – The Lancet

Conteúdos relacionados:

Tocilizumab versus baricitinib in hospitalized patients with severe COVID-19: an open label, randomized controlled trial – medRxiv

Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial – The Lancet Respiratory Medicine

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis – medRxiv

WHO recommends two new drugs to treat COVID-19 – World Health Organization

Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial – The Lancet Respiratory Medicine

Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 – New England Journal of Medicine

Comentário no Twitter

New @TheLancet
The largest trial of baricitinib, a JAK-inhibitor drug repurposed via #AI data mining, reduced Covid mortality and the overall reduction consistent with 8 previous RCTs (~20%)https://t.co/5fHDBBvm3Q pic.twitter.com/GDFzcU26H6

— Eric Topol (@EricTopol) July 29, 2022

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