Terapia Intensiva

Estudo randomizado | Controle da hipotensão pós-cirúrgica usando um sistema fechado de infusão de norepinefrina em pacientes submetidos a cirurgia cardíaca.

28 Jan, 2022 | 16:56h

Control of Postoperative Hypotension Using a Closed-Loop System for Norepinephrine Infusion in Patients After Cardiac Surgery: A Randomized Trial – Anesthesia & Analgesia (link para o resumo – $ para o texto completo)

Conteúdo relacionado: RCT: Computer-assisted individualized hemodynamic management reduces intraoperative hypotension in intermediate- and high-risk surgery – larger trials with patient-relevant outcomes are required.

Estudo laboratorial mostra que novas pílulas antivirais mantêm sua eficácia contra a variante Ômicron, mas anticorpos monoclonais são substancialmente menos efetivos.

28 Jan, 2022 | 16:28h

Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant – New England Journal of Medicine

Comentário: Current anti-COVID pills work well against omicron, but antibody drugs are less effective, study finds – University of Wisconsin-Madison

Comentário no Twitter

Investigators assessed the in vitro activities of seven monoclonal antibodies & three antiviral drugs against #COVID19 variants. All antibodies showed no or weak neutralizing activity against omicron; two drugs effective at omicron neutralization. https://t.co/rOZzmtsDZS pic.twitter.com/shfKDW6r5q

— NEJM (@NEJM) January 26, 2022

Casos de transplante de pulmão para insuficiência respiratória relacionada a Covid-19 nos EUA foram associados com sobrevida de 3 meses de 95,6%.

28 Jan, 2022 | 16:26h

Lung Transplantation for Covid-19–Related Respiratory Failure in the United States – New England Journal of Medicine

Comentários:

New data on COVID-19 lung transplants – Cedars-Sinai Medical Center

~7 Percent of Lung Transplants Due to COVID-19 Respiratory Failure – HealthDay

Ampla revisão do tratamento com dreno torácico.

28 Jan, 2022 | 16:16h

Comprehensive Review of Chest Tube Management – JAMA Surgery (gratuito por tempo limitado)

M-A | Não há evidência suficiente de que a suplementação de micronutrientes aliada a suporte nutricional padrão melhore os desfechos clínicos de pacientes internados com desnutrição.

28 Jan, 2022 | 16:11h

Effect of micronutrient supplementation in addition to nutritional therapy on clinical outcomes of medical inpatients: results of an updated systematic review and meta-analysis – European Journal of Clinical Nutrition (link para o resumo – $ para o texto completo)

Controvérsias e falta de evidências sobre o tratamento inicial da lesão cerebral traumática grave: de volta ao básico.

28 Jan, 2022 | 16:04h

Controversies and evidence gaps in the early management of severe traumatic brain injury: back to the ABCs – Trauma Surgery & Acute Care Open

Estudo de coorte | Entre sobreviventes de tratamento em UTI para COVID-19, 75% ainda relatam sintomas físicos, mentais e cognitivos depois de 1 ano.

28 Jan, 2022 | 15:45h

Clinical Outcomes Among Patients With 1-Year Survival Following Intensive Care Unit Treatment for COVID-19 – JAMA

Comentários:

75% of COVID ICU survivors have physical symptoms 1 year on – CIDRAP

Majority of COVID-19 survivors experience health problems one-year post ICU admission – News Medical

Diretrizes sobre o tratamento da dissecção de aorta tipo B.

28 Jan, 2022 | 15:33h

The Society of Thoracic Surgeons/American Association for Thoracic Surgery Clinical Practice Guidelines on the Management of Type B Aortic Dissection – Annals of Thoracic Surgery

Comunicado de imprensa: New practice guideline addresses diagnosis, treatment of type B aortic dissection – The Society of Thoracic Surgeons

Edição especial: medicina de vítimas em massa e anestesia.

28 Jan, 2022 | 15:32h

Editoriais:

Mass casualty medicine: time for a 21st century refresh

Exercising for mass casualty preparedness

Massive transfusion and severe blood shortages: establishing and implementing predictors of futility

Transfusion support during mass casualty events

Embracing uncertainty in mass casualty incidents

Pre-hospital critical care at major incidents

Provision of pre-hospital medical care for terrorist attacks

Higher pre-hospital anaesthesia case volumes result in lower mortality rates: implications for mass casualty care

Improving mass casualty planning in low resource settings: Médecins Sans Frontières and International Committee of the Red Cross perspective

Global lessons learned from COVID-19 mass casualty incidents

Reimagining health preparedness in the aftermath of COVID-19

Preparing for mass casualty events despite COVID-19

Anestesia pediátrica:

Paediatric patients in mass casualty incidents: a comprehensive review and call to action

Adaptations to practice and resilience in a paediatric major trauma centre during a mass casualty incident

Cuidado pré-hospitalar:

Injury scoring systems for blast injuries: a narrative review

Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort

Establishing quality indicators for pre-hospital advanced airway management: a modified nominal group technique consensus process

Pre-hospital continuous positive airway pressure after blast lung injury and hypovolaemic shock: a modelling study

Preparo:

Review of the requirements for effective mass casualty preparedness for trauma systems. A disaster waiting to happen?

Learning from terrorist mass casualty incidents: a global survey

Refining mass casualty plans with simulation-based iterative learning

Incidentes específicos:

Mass casualty, intentional vehicular trauma and anaesthesia

Chemical, biological, radiological, and nuclear mass casualty medicine: a review of lessons from the Salisbury and Amesbury Novichok nerve agent incidents

Correspondência:

Pre-hospital oral transmucosal fentanyl citrate for trauma analgesia: preliminary experience and implications for civilian mass casualty response

Implications for trauma system development in a low- and middle-income country: the Sri Lanka 2019 Easter Sunday terrorist attack

Development and evaluation of a mass casualty medicine simulation method using figurines

Influx! A game-based learning tool for in-hospital interprofessional disaster preparedness and response

Um estudo de registro com 1.581 casos de Stenotrophomonas maltophilia sanguínea e/ou infecções de trato respiratório inferior sugere que levofloxacino é uma alternativa razoável à terapia padrão com trimetoprima-sulfametoxazol.

28 Jan, 2022 | 15:19h

Trimethoprim-Sulfamethoxazole versus Levofloxacin for Stenotrophomonas maltophilia Infections: A Retrospective Comparative Effectiveness Study of Electronic Health Records from 154 U.S. Hospitals – Open Forum Infectious Diseases