Acesso livre
Acesso livre

Terapia Intensiva

M-A | Desfechos similares de betalactâmico em monoterapia vs. terapia combinada para infecções de corrente sanguínea ou pneumonia por Pseudomonas aeruginosa.

15 Mar, 2022 | 13:02h

Beta-lactam monotherapy or combination therapy for bloodstream infections or pneumonia due to Pseudomonas aeruginosa: a meta-analysis – International Journal of Antimicrobial Agents (link para o resumo – $ para o texto completo)

Podcast | Dicas sobre síndrome cardiorrenal.

15 Mar, 2022 | 12:57h

#326 NephMadness 2022: Cardiorenal Syndrome – The Curbsiders

Metanálise de estudos randomizados comparando estratégias de transfusão de hemácias intraoperatória.

14 Mar, 2022 | 14:07h

A Systematic Review and Meta-analysis of Randomized Controlled Trials Comparing Intraoperative Red Blood Cell Transfusion Strategies – Annals of Surgery

Conteúdos relacionados:

Systematic Review: Restrictive transfusion thresholds can safely decrease transfusions by 41% across a broad range of clinical contexts.

RCT: Among patients with acute MI and anemia, a restrictive transfusion strategy resulted in a noninferior rate of major cardiovascular events compared to a liberal transfusion strategy

Randomized trial: Liberal vs. restrictive transfusion thresholds in extremely low-birth-weight infants

Meta-Analysis: Effects of Restrictive vs. Liberal Transfusion Strategies on Longer-term Outcomes After Cardiac Surgery

Randomized Trial: In Patients Undergoing Cardiac Surgery, A Restrictive Transfusion Approach Does Not Increase the Risk of Acute Kidney Injury

Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials – Critical Care

Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA

Revisão sistemática e metanálise bayesiana | Temperatura-alvo após parada cardíaca.

14 Mar, 2022 | 13:45h

Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis – Critical Care

Conteúdos relacionados:

ERC-ESICM guidelines on temperature control after cardiac arrest in adults.

M-A: In comatose survivors of cardiac arrest, targeted hypothermia is not associated with improved survival or better neurological outcomes vs. targeted normothermia.

RCT: In comatose survivors of out-of-hospital cardiac arrest, there was no difference in mortality and neurologic outcomes with mild (target temperature of 34 °C) vs. moderate therapeutic hypothermia (target temperature of 31 °C).

M-A: Targeted temperature management following out-of-hospital cardiac arrest – “Routine use of moderate or deep hypothermia in comatose survivors of OHCA may potentially be associated with more harm than benefit”.

RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

Infecções associadas a cuidados de saúde em pacientes adultos de UTI: mudanças em epidemiologia, diagnóstico, prevenção e contribuição das novas tecnologias.

14 Mar, 2022 | 13:44h

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies – Intensive and Critical Care Nursing

Estudo randomizado | Efetividade da fosfomicina no tratamento de infecções de trato urinário por Escherichia coli multirresistente.

14 Mar, 2022 | 13:37h

Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections: A Randomized Clinical Trial – JAMA Network Open

Comentários:

The Role of Intravenous Fosfomycin: Finding Our Way Out of Dante’s Forest Dark – JAMA Network Open

Fosfomycin Not Noninferior to Comparators for Bacteremic UTI – HealthDay

‘Forgotten’ antibiotic recovered for resistant bacterial infections – University of Seville

 

Comentário no Twitter

 

Revisão | Lesão renal aguda induzida por medicamentos.

14 Mar, 2022 | 13:27h

Drug-Induced Acute Kidney Injury – Clinical Journal of the American Society of Nephrology

Tratamento da insuficiência respiratória: tratamento com ventilador 101 e ventilação não invasiva.

14 Mar, 2022 | 13:26h

Management of Respiratory Failure: Ventilator Management 101 and Noninvasive Ventilation – Clinical Journal of the American Society of Nephrology

Estudo randomizado | Segurança e eficácia de 3 estratégias de nutrição enteral em pacientes com AVC grave.

11 Mar, 2022 | 14:59h

Safety and efficacy of three enteral feeding strategies in patients with severe stroke in China (OPENS): a multicentre, prospective, randomised, open-label, blinded-endpoint trial – The Lancet Neurology (link para o resumo – $ para o texto completo)

Associação entre uso de estatinas e eventos adversos musculoesqueléticos relacionados à daptomicina: uma abordagem mista combinando metanálise e análise de desproporcionalidade.

11 Mar, 2022 | 14:50h

Association between statin use and daptomycin-related musculoskeletal adverse events: A mixed approach combining a meta-analysis and a disproportionality analysis – Clinical Infectious Diseases

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