Acesso livre
Acesso livre

Saúde Pública/Medicina Humanitária

Pílulas antivirais contra COVID: o que os cientistas ainda precisam saber – “Medicações como molnupiravir e paxlovid podem mudar o curso da pandemia se os resultados de ensaios clínicos se repetirem no mundo real.”

11 Nov, 2021 | 16:23h

COVID antiviral pills: what scientists still want to know – Nature

Conteúdos relacionados:

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

A prominent virologist warns new COVID-19 pill could unleash dangerous mutants. Others see little cause for alarm.

The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.

Merck to allow other nations to produce new COVID-19 antiviral.

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.


Perspectiva | Como será o fim da pandemia: cientistas têm pistas sobre a evolução do SARS-CoV-2.

11 Nov, 2021 | 16:20h

COVID’s endgame: Scientists have a clue about where SARS-CoV-2 is headed – NPR


Consenso | Avanço na agenda de saúde pública global para doença hepática gordurosa não alcoólica.

11 Nov, 2021 | 16:15h

Advancing the global public health agenda for NAFLD: a consensus statement – Nature Reviews Gastroenterology & Hepatology

Conteúdos relacionados:

Clinical Care Pathway for the Risk Stratification and Management of Patients with Nonalcoholic Fatty Liver Disease.

Non-alcoholic fatty liver disease: A patient guideline.

State of the art review: Management of non-alcoholic fatty liver disease

M-A: Non-alcoholic fatty liver disease linked to increased risk of fatal and non-fatal cardiovascular events.

M-A: non-invasive tests for advanced fibrosis can reduce the need for biopsy in patients with non-alcoholic fatty liver disease.

Review: Dietary carbohydrates and fats in nonalcoholic fatty liver disease.

 

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Estudo randomizado | Rastreamento universal no ensino médio pode ajudar a identificar e iniciar o tratamento de depressão em adolescentes.

11 Nov, 2021 | 16:00h

Screening in High Schools to Identify, Evaluate, and Lower Depression Among Adolescents: A Randomized Clinical Trial – JAMA Network Open

Comunicado de imprensa: School-based screening increases identification of, treatment for depression – Penn State

Comentários:

Universal Depression Screening in Schools—Promises and Challenges in Addressing Adolescent Mental Health Need – JAMA Network Open

Universal School-Based Depression Screening May Connect More Students to Care – Psychiatric News Alert

 

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Estudo randomizado | Vacina da Pfizer mostra 90,7% de eficácia na prevenção de Covid-19 em crianças de 5 a 11 anos de idade.

10 Nov, 2021 | 12:55h

Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age – New England Journal of Medicine

 

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Como um surto se tornou uma pandemia: análise cronológica de conjunturas cruciais e obrigações internacionais nos meses iniciais da pandemia de COVID-19.

10 Nov, 2021 | 12:53h

How an outbreak became a pandemic: a chronological analysis of crucial junctures and international obligations in the early months of the COVID-19 pandemic – The Lancet

 

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Autoridade de saúde da França faz recomendações contra o uso da vacina da Moderna em menores de 30 anos de idade.

10 Nov, 2021 | 12:50h

French Health Authority Advises Against Moderna COVID-19 Vaccine for Under 30s – Reuters

Ver também: France advises against Moderna for under-30s over rare heart risk – Associated Press

Conteúdo relacionado: Sweden, Denmark pause Moderna COVID-19 vaccine for younger age groups.

 

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Podemos ter certeza de que houve mais de 5 milhões de mortes por Covid no mundo – “Estimar fatalidades ‘em excesso’, um método de análise mais robusto, mostra que a pandemia custou de 10 milhões a 19 milhões de vidas.”

9 Nov, 2021 | 12:21h

We can be confident there have been far more than 5 million global Covid deaths – The Guardian

Conteúdos relacionados:

Global Covid-19 deaths surpass five million.

Effects of the Covid-19 pandemic on life expectancy and premature mortality in 2020 – this time series analysis showed there were more than 28 million excess years of life lost in 2020 in 31 countries.

Under-reporting of deaths limits our understanding of true burden of covid-19.

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show


Como as vacinas contra COVID baseadas em proteína podem mudar a pandemia.

9 Nov, 2021 | 12:19h

How protein-based COVID vaccines could change the pandemic – Nature


Sprays nasais, adesivos livres de agulhas, imunidade duradoura: a próxima geração de vacinas contra COVID.

9 Nov, 2021 | 12:18h

Nose sprays, needle-free patches, durable immunity: towards the next generation of COVID vaccines – The Conversation

 


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