Revisões Sistemáticas
Prevenção de natimortos: quais são as evidências mais recentes?
25 Ago, 2021 | 12:55hPreventing stillbirth: What’s the latest evidence? – Evidently Cochrane
Coleção especial: Stillbirth prevention and respectful bereavement care – Cochrane Library
Comentário no Twitter (fio – clique para saber mais)
New @CochraneLibrary Special Collection on #stillbirth prevention and respectful bereavement care: https://t.co/NW37SaUhr3 1/5#stillborn #babyloss #miscarriage #pregnancyloss #infantloss #pregnancyandinfantloss pic.twitter.com/mzIe3Sttwk
— The Cochrane Library (@CochraneLibrary) August 24, 2021
M-A | Agonistas receptores de GLP-1 reduzem eventos cardiovasculares adversos maiores, mortalidade por todas as causas, admissão hospitalar por insuficiência cardíaca e piora na função renal em pacientes com diabetes tipo 2.
23 Ago, 2021 | 12:58hCardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials – The Lancet Diabetes & Endocrinology (link para o resumo – $ para o texto completo)
M-A | O papel dos inibidores de SGLT2 na insuficiência cardíaca.
23 Ago, 2021 | 12:56hConteúdos relacionados:
ESC Position Paper: Cardiac, renal, and metabolic effects of SGLT2 inhibitors.
Summary: SGLT2 inhibitors and GLP-1 receptor agonists established and emerging indications.
M-A | Dose necessária de drogas antipsicóticas para prevenção de recaídas em pacientes com esquizofrenia estável.
20 Ago, 2021 | 12:19hExamination of Dosing of Antipsychotic Drugs for Relapse Prevention in Patients With Stable Schizophrenia: A Meta-analysis – JAMA Psychiatry (gratuito por tempo limitado)
Comentários no Twitter
Crucial literature review on optimal antipsychotic dosing for long term maintenance in #Schizophrenia.
Conclusion: Seek Goldilocks "just right"- definitely not high because of bad side effects, but not so low as to risk relapse.
Often easier said than done. https://t.co/RBBPBMzn9D
— Allen Frances (@AllenFrancesMD) August 20, 2021
Doses higher than 5mg/day risperidone equivalent are not more effective for relapse prevention than lower doses in #schizophrenia. But caution is required at the lower end of the dose-response curve where relapse risk disproportionally increases https://t.co/kQcnuRtzYU
— JAMA Psychiatry (@JAMAPsych) August 19, 2021
M-A | Prevalência, tratamento e impacto da doença pulmonar obstrutiva crônica na fibrilação atrial.
20 Ago, 2021 | 12:18hPrevalence, management and impact of chronic obstructive pulmonary disease in atrial fibrillation: a systematic review and meta-analysis of 4,200,000 patients – European Heart Journal (link para o resumo – $ para o texto completo)
Comentário no Twitter
AF-COMET Meta-analysis showed #COPD is common in #AF, being found in 13% of patients
📌⬆️ burden of comorbidities & worse outcomes
📌More than a two-fold ⬆️ risk of all-cause death
📌⬆️ Risk of CV death and major bleedinghttps://t.co/fLAuGkQAX1 @ESC_Journals @SchakrabartiEP pic.twitter.com/50OSfACH84— Henry Han, MBBS, MD (@HanCardiomd) August 2, 2021
M-A de estudos randomizados | O efeito de maior ou menor aporte proteico em pacientes criticamente doentes – “Nesses pacientes, um alto aporte diário de proteína não esteve associado com qualquer melhora nos desfechos clínicos ou centrados no paciente.”
20 Ago, 2021 | 12:16hSuperfícies de apoio para o tratamento de úlceras de pressão: quais escolher?
18 Ago, 2021 | 12:24hSupport surfaces for managing pressure ulcers: which to choose? – Evidently Cochrane
Revisão sistemática | Corticosteroides sistêmicos para tratamento de COVID-19.
17 Ago, 2021 | 11:39hSystemic corticosteroids for the treatment of COVID‐19 – Cochrane Library
Comentário no Twitter (fio – clique para saber mais)
JUST PUBLISHED – Systemic #corticosteroids for the treatment of #COVID19 from @CochraneHaem – https://t.co/l4V993gLzj 1/5 pic.twitter.com/Vjk4aHXKFV
— The Cochrane Library (@CochraneLibrary) August 16, 2021
M-A | Abordagem da temperatura-alvo após parada cardíaca fora do ambiente hospitalar – “O uso rotineiro de hipotermia moderada ou profunda em sobreviventes comatosos pode estar potencialmente associado com mais dano do que benefício.”
16 Ago, 2021 | 11:50hTargeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets – Intensive Care Medicine (gratuito por tempo limitado)
Conteúdo relacionado: RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.
Comentário no Twitter
#TTM post #OHCA, SR/NMA:
❄️deep, moderate & mild hypothermia not improve survival/functional outcome vs normothermia
❄️deep vs moderate hypothermia may not improve survival with good outcome
❄️higher incidence of arrhythmia with moderate & deep hypothermiahttps://t.co/Z18v5HSXyr pic.twitter.com/6TQf8QPKiA— Intens Care Med (@yourICM) August 14, 2021
Revisão sistemática | Alimentação por sonda enteral em pessoas com demência grave – “Não há evidências de que a alimentação enteral melhore a sobrevida e a qualidade de vida, e reduza a dor, a mortalidade e os sintomas psicológicos e comportamentais da demência.”
16 Ago, 2021 | 11:48hEnteral tube feeding for people with severe dementia – Cochrane Library
Resumo: Enteral tube feeding for people with severe dementia – Cochrane Library
Conteúdo relacionado: Viewpoint: Tube Feeding and Deteriorating Patients (fontes sobre o tema)
Comentário no Twitter
🚨🚨So happy our @CochraneUK review on enteral tube feeding in #dementia is now published – no evidence tube feeding improves #survival; improves quality of life; reduces #pain; reduces #mortality. But was evidence of increase risk of pressure ulcers https://t.co/uUHJEboNCd
— Nathan Davies (@NathanDavies50) August 13, 2021