Reumatologia

Estudo randomizado | Eficácia e segurança do upadacitinibe para espondilite anquilosante ativa refratária à terapia biológica.

8 Jul, 2022 | 11:15h

Efficacy and safety of upadacitinib for active ankylosing spondylitis refractory to biological therapy: a double-blind, randomised, placebo-controlled phase 3 trial – Annals of Rheumatic Diseases

 

Comentário no Twitter

SELECT-AXIS 2 trial – patients with #AS and inadequate response to #bDMARDs. #RCT of upadacitinb vs placebo 14 weeks:
Improved signs and symptoms of active AS and was well tolerated for 14 weeks of treatment in bDMARD-IR patients!https://t.co/Z7fuxiXMDb pic.twitter.com/kGZX9AsaVE

— ARD & RMD Open (@ARD_BMJ) July 5, 2022

 

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Análise post-hoc | Os inibidores de SGLT2 são capazes de reduzir o risco de hiperuricemia e gota?

8 Jul, 2022 | 11:12h

Uric acid and sodium-glucose cotransporter-2 inhibition with empagliflozin in heart failure with reduced ejection fraction: the EMPEROR-reduced trial – European Heart Journal

 

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Estudo de coorte baseado em registro | Associação entre gota e desfechos cardiovasculares em adultos sem histórico de doença cardiovascular.

8 Jul, 2022 | 11:06h

Association between gout and cardiovascular outcomes in adults with no history of cardiovascular disease: large data linkage study in New Zealand – BMJ Medicine

 

Comentário no Twitter

Read now the latest research on the association between gout and #CardiovascularOutcomes.▶️ https://t.co/DV4BYXWAZI#BMJMedicine #CardivascularEvents #MedTwitter
Highlights below ⬇️ pic.twitter.com/lDc1Y2Vt0E

— BMJMedicine (@BMJMedicine) July 5, 2022

 

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Estudo randomizado | Ozoralizumabe vs. placebo em pacientes com artrite reumatoide ativa a despeito da terapia com metotrexato.

7 Jul, 2022 | 11:49h

Phase II/III results of the anti-TNF multivalent NANOBODY® compound ‘ozoralizumab’ in patient with rheumatoid arthritis (OHZORA trial) – Arthritis & Rheumatology

Comentário:

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Revisão sistemática | Nenhuma evidência apoia a meniscectomia parcial artroscópica em adultos com sintomas meniscais degenerativos e não obstrutivos.

6 Jul, 2022 | 10:48h

No evidence in support of arthroscopic partial meniscectomy in adults with degenerative and nonobstructive meniscal symptoms: a level I evidence-based systematic review – Knee Surgery, Sports Traumatology, Arthroscopy

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Diretriz de consenso | Recomendações atualizadas de tratamento da artrite psoriática.

5 Jul, 2022 | 11:43h

Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): updated treatment recommendations for psoriatic arthritis 2021 – Nature Reviews Rheumatology (se o acesso a este link for pago, tente este no PMC Central)

Ver também (recém-publicado): Update on the Management of Pediatric Psoriasis: An Italian Consensus – Dermatology and Therapy

Conteúdos relacionados:

The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs – Rheumatology

Resumo executivo: The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs – Rheumatology

EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update – Annals of Rheumatic Diseases

2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis – Arthritis Care & Research

Spondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline

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Análise secundária do estudo Global Burden of Disease 2019 | Impacto global de distúrbios musculoesqueléticos e fatores atribuíveis em 204 países de territórios.

5 Jul, 2022 | 11:38h

Global burden of musculoskeletal disorders and attributable factors in 204 countries and territories: a secondary analysis of the Global Burden of Disease 2019 study – BMJ Open

Conteúdo relacionado: The Global Burden of Musculoskeletal Pain—Where to From Here? – American Journal of Public Health

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Revisão | Redução e aumento dos níveis de urato sérico: efeitos off-label de medicações comumente usadas.

5 Jul, 2022 | 11:26h

Lowering and Raising Serum Urate Levels: Off-Label Effects of Commonly Used Medications – Mayo Clinic Proceedings

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Guia para prevenção e tratamento da osteoporose.

21 Jun, 2022 | 12:57h

The clinician’s guide to prevention and treatment of osteoporosis – Osteoporosis International

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Estudo randomizado | Suplementação de ácido graxo ômega 3 de origem marinha não reduz a incidência de olho seco em adultos saudáveis.

16 Jun, 2022 | 14:00h

Efficacy of Marine ω-3 Fatty Acid Supplementation vs Placebo in Reducing Incidence of Dry Eye Disease in Healthy US Adults: A Randomized Clinical Trial – JAMA Ophthalmology (gratuito por tempo limitado)

Comentário convidado: Another Disappointment for ω-3 Fatty Acid and Dry Eye Disease – JAMA Ophthalmology (gratuito por tempo limitado)

 

Comentário no Twitter

In this randomized clinical trial, daily supplementation with marine omega-3 fatty acids (1 gram) for a median of 5.3 years had no significant effect on the incidence of diagnosed #dryeyedisease (DED) or reported DED symptoms. https://t.co/iTBONh6CZK

— JAMAOphthalmology (@JAMAOphth) June 9, 2022

 

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