Psiquiatria

M-A | Dose necessária de drogas antipsicóticas para prevenção de recaídas em pacientes com esquizofrenia estável.

20 Ago, 2021 | 12:19h

Examination of Dosing of Antipsychotic Drugs for Relapse Prevention in Patients With Stable Schizophrenia: A Meta-analysis – JAMA Psychiatry (gratuito por tempo limitado)

 

Comentários no Twitter

Crucial literature review on optimal antipsychotic dosing for long term maintenance in #Schizophrenia.

Conclusion: Seek Goldilocks "just right"- definitely not high because of bad side effects, but not so low as to risk relapse.

Often easier said than done. https://t.co/RBBPBMzn9D

— Allen Frances (@AllenFrancesMD) August 20, 2021

Doses higher than 5mg/day risperidone equivalent are not more effective for relapse prevention than lower doses in #schizophrenia. But caution is required at the lower end of the dose-response curve where relapse risk disproportionally increases https://t.co/kQcnuRtzYU

— JAMA Psychiatry (@JAMAPsych) August 19, 2021

 

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Conforme tem aumentado o uso de estimulantes, especialistas veem paralelos preocupantes com a crise de opioides.

19 Ago, 2021 | 12:09h

As use of widely prescribed stimulants increases, experts see troubling parallels to opioid crisis – STAT

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Nove em cada 10 crianças com transtorno do déficit de atenção com hiperatividade (TDAH) pode experimentar sintomas ao entrarem na idade adulta.

19 Ago, 2021 | 12:07h

Nine in Ten Children With ADHD May Experience Symptoms Into Young Adulthood – Psychiatric News Alert

Estudo original: Variable Patterns of Remission From ADHD in the Multimodal Treatment Study of ADHD – The American Journal of Psychiatry

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[Preprint] Impacto da pandemia de COVID-19 sobre o desenvolvimento cognitivo na primeira infância: achados iniciais de um estudo observacional longitudinal sobre a saúde infantil.

16 Ago, 2021 | 12:01h

Impact of the COVID-19 Pandemic on Early Child Cognitive Development: Initial Findings in a Longitudinal Observational Study of Child Health – medRxiv

Comentário: Children born during pandemic have lower IQs, US study finds – Researchers blame lack of stimulation as parents balanced childcare with working from home – The Guardian

 

Comentário no Twitter (fio – clique para saber mais)

Preprint on the development of children born before and during the pandemic in the US.

"We find that children born during the pandemic have significantly reduced verbal, motor, and overall cognitive performance compared to children born pre-pandemic."
1/https://t.co/NInexSUDAi

— Prof Francois Balloux (@BallouxFrancois) August 15, 2021

 

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Opinião | Um chamado para a revisão do diagnóstico do transtorno desafiador de oposição – diagnósticos são para ajudar, não para causar danos.

16 Ago, 2021 | 11:42h

A Call to Revise the Diagnosis of Oppositional Defiant Disorder—Diagnoses Are for Helping, Not Harming – JAMA Psychiatry (gratuito por tempo limitado)

 

Comentário no Twitter

Can giving someone a diagnosis (more accurately, a diagnostic label) cause harm? Undoubtedly; an example is discussed in this article https://t.co/13RysG9Yxa In rehabilitation, the term 'functional disorder' often stigmatises, & many labels generate unfair expectations in others

— Derick Wade (@derickwaderehab) August 14, 2021

 

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Diretriz europeia sobre o tratamento da narcolepsia em adultos e crianças.

13 Ago, 2021 | 12:12h

European guideline and expert statements on the management of narcolepsy in adults and children – European Journal of Neurology

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M-A | Mais de 50 efeitos de longo prazo da COVID-19.

11 Ago, 2021 | 10:57h

More than 50 long-term effects of COVID-19: a systematic review and meta-analysis – Scientific Reports

Conteúdos relacionados:

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Cohort study: Risk factors for long covid in previously hospitalized children.

Viewpoint: The road to addressing Long Covid.

Review: Long covid—mechanisms, risk factors, and management.

Review: Symptoms, complications and management of long COVID.

Long Covid: fatigue, post-exertional malaise, and cognitive dysfunction are the most common symptoms, according to an international survey.

Studies elucidate poorly understood long COVID.

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Long Covid: 39% of patients report persistent symptoms more than seven months after diagnosis of COVID-19 in an outpatient setting.

[Preprint] Long Covid: Persistent symptoms following SARS-CoV-2 infection in a random community sample of 508,707 people.

Long COVID or post-acute sequelae of COVID-19 (PASC): An overview of biological factors that may contribute to persistent symptoms.

Long Covid: Half of young adults with COVID-19 have persistent symptoms 6 months after, study finds.

[Preprint] Long Covid: Third of people infected have long term symptoms.

Opinion | Causation or confounding: why controls are critical for characterizing long COVID – “Many of the self-reported symptoms, such as intermittent headaches or tiredness, are nonspecific and prevalent in the general population”.

Almost 25% of COVID-19 patients develop long-lasting symptoms, according to a new report.

Perspective | The four most urgent questions about long COVID.

Systematic review: Frequency, signs and symptoms, and criteria adopted for long COVID-19.

Report: 376,000 people in UK have had long Covid symptoms for at least a year.

Systematic review of 45 studies including 9751 participants, most of which were hospitalized, found 73% had at least 1 persistent symptom for weeks after Covid-19.

COVID Morbidity – The emerging burden of long COVID is significant, and needs to be considered when evaluating the risk vs. benefit of pandemic measures.

One year after hospital discharge due to SARS-CoV-2 Infection, the prevalence of long-term cough, chest pain, dyspnea, and fatigue was 2.5%, 6.5%, 23.3%, and 61.2%, respectively

Population-based cohort study: Non-hospitalized COVID-19 patients have low-risk of serious long-term effects, but visits to general practitioners and outpatient hospital visits are increased.

One third of patients hospitalized with COVID-19 have lung changes after a year

Long Covid: Largest post-acute COVID-19 study to date examined the health outcomes in more than 73,000 people who’d had COVID-19 and were not hospitalized

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Perspective | They Tested Negative for Covid. Still, They Have Long Covid Symptoms.

Large study finds 1 in 3 Covid-19 survivors have subsequent mental health and neurological conditions

Cohort study: One in ten have long-term effects 8 months following mild COVID-19

Long Covid Implications for the workplace

Long Covid in the UK – More than a million affected in February, survey suggests

Covid-19: Middle aged women face greater risk of debilitating long term symptoms

Persistent neurologic symptoms and cognitive dysfunction in non‐hospitalized Covid‐19 “long haulers”

Opinion | We need to start thinking more critically — and speaking more cautiously — about long Covid

Review | Post-acute COVID-19 syndrome

Long Covid | Four-month clinical status of a cohort of patients after hospitalization for COVID-19

Perspective | Long Covid isn’t as unique as we thought

Attributes and predictors of long COVID

WHO Report: Preparing for Long COVID 2021

Long Covid: Sequelae in adults at 6 Months after COVID-19 infection

How many people get ‘long COVID’ – and who is most at risk?

Long Covid: Respiratory and psychophysical sequelae among patients with COVID-19 four months after hospital discharge

Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline

Patients, clinicians seek answers to the mystery of ‘Long COVID’

Long Covid: 6-month consequences of COVID-19 in patients discharged from hospital

[Preprint] Characterizing Long COVID in an International Cohort: 7 Months of Symptoms and Their Impact

NICE Guideline: Managing the long-term effects of COVID-19

 

Comentário no Twitter

Nuestro estudio sobre Covid 🦠Persistente o de Largo recorrido se ha publicado finalmente en @SciReports
👉https://t.co/ATFO5QO3kF pic.twitter.com/qwBikXyqll

— Sonia Villapol (@svillapol) August 10, 2021

 

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Novas ferramentas da OMS para a inclusão de pessoas com demência na sociedade.

11 Ago, 2021 | 10:39h

New WHO toolkit promotes inclusion of people with dementia in society – World Health Organization

Ver Diretriz: Towards a dementia inclusive society: WHO toolkit for dementia-friendly initiatives (DFIs) – World Health Organization

 

Comentário no Twitter (fio – clique para saber mais)

🆕 toolkit to promote a #dementia-inclusive society launched. It will helps countries raise public awareness and understanding of dementia to support people living with dementia to remain in, and be a significant part of, their communities.

👉 https://t.co/blpDQHUSWM pic.twitter.com/D5MIM5jdlr

— World Health Organization (WHO) (@WHO) August 10, 2021

 

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M-A | Problemas de saúde mental em crianças e jovens dobraram durante a COVID-19.

10 Ago, 2021 | 12:49h

Comentário: Child and youth mental health problems have doubled during COVID-19 – The Conversation

Estudo original: Global Prevalence of Depressive and Anxiety Symptoms in Children and Adolescents During COVID-19: A Meta-analysis – JAMA Pediatrics

Editorial: Addressing the Global Crisis of Child and Adolescent Mental Health – JAMA Pediatrics

Conteúdos relacionados:

More data on the harmful effects of the COVID-19 pandemic on the mental health of adolescents.

COVID has caused ‘mass trauma,’ worsening mental health globally.

COVID’s mental-health toll: how scientists are tracking a surge in depression

CDC Report: Mental health-related emergency department visits among children aged under 18 years raised during the COVID-19 Pandemic

WHO: COVID-19 disrupting mental health services in most countries

 

Comentário no Twitter (fio – clique para saber mais)

Many are rightfully sounding the alarm to a youth #mentalhealth crisis. Our meta-analysis of 29 studies w >80,000 youth worldwide in @JAMAPediatrics, shows 1 in 4 youth had elevated depression or anxiety during #COVID19. A thread 🧵 https://t.co/etIdZTHnme

— Dr. Sheri Madigan (she/her) (@sherimadigan) August 9, 2021

 

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Perspectiva | Experiência de fora da Academia: redução de antidepressivos.

9 Ago, 2021 | 11:06h

Expertise from outside the Academy: tapering off antidepressants – The Mental Elf

Conteúdos relacionados:

A method for tapering antipsychotic treatment that may minimize the risk of relapse

Systematic Review: Managing Antidepressant Discontinuation

Randomized controlled trial: preventive cognitive therapy for prevention of depressive recurrence

M-A: Continuation of antidepressants vs. sequential psychological interventions to prevent relapse in depression.

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