Pneumologia Pediátrica
Risco de reinfecções por SARS-CoV-2 em crianças: um estudo de vigilância nacional prospectiva na Inglaterra.
1 Abr, 2022 | 12:24hComentário convidado: Importance of understanding the reinfection risk of COVID-19 in children – The Lancet Child & Adolescent Health
Comentário no Twitter
Everything we know about #SARSCoV2 tells us that first infection reduces (but doesn’t eliminate) the risk & SEVERITY of further infections, even with new variants. Here is our paper showing this with delta reinfections in kids (work on omicron reinfections in progress)👇 https://t.co/3gDPBHRu18
— Shamez Ladhani (@ShamezLadhani) March 30, 2022
Estudo randomizado | Entre prematuros com idade gestacional menor que 30 semanas e entubados por pelo menos 7 e nascidos de 14 a 28 dias, hidrocortisona não melhorou a sobrevida sem displasia broncopulmonar.
25 Mar, 2022 | 15:03hHydrocortisone to Improve Survival without Bronchopulmonary Dysplasia – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Ver também: Visual Abstract
Conteúdos relacionados:
State of the Art Review: Diagnosis and management of bronchopulmonary dysplasia.
ERS Guideline on Long-term Management of Children with Bronchopulmonary Dysplasia
Comentário no Twitter
In this trial involving preterm infants, there was little difference in survival without bronchopulmonary dysplasia or in the occurrence of neurodevelopmental impairment with hydrocortisone as compared with placebo. https://t.co/wzGQ1gohjA pic.twitter.com/yfrIaG3JLv
— NEJM (@NEJM) March 23, 2022
Estudo de caso-controle | Efetividade da vacina da Pfizer contra COVID-19 em adolescentes.
25 Mar, 2022 | 14:55hEffectiveness of BNT162b2 against COVID-19 in adolescents – The Lancet Infectious Diseases
Comentário no Twitter
Our paper on #COVID19 vaccine effectiveness in teenagers (12-17y) is published @TheLancetInfDis. Rapid waning of protection against symptomatic disease, esp with omicron. Vaccines did reduce delta hospitalisations but too early to assess omicron effects
— Shamez Ladhani (@ShamezLadhani) March 23, 2022
Primeira estimativa global sugere que impostos mais altos sobre cigarros poderiam reduzir mortes infantis.
25 Mar, 2022 | 14:37hComunicado de imprensa: Higher cigarette taxes reduce child deaths, first global estimates suggest – Imperial College London
Estudo original: Cigarette taxation and neonatal and infant mortality: A longitudinal analysis of 159 countries – PLOS Global Public Health
Novas diretrizes da OMS sobre o tratamento da tuberculose em crianças e adolescentes.
23 Mar, 2022 | 12:10hConteúdo relacionado: RCT: In children with nonsevere, drug-susceptible tuberculosis, treatment for 4 months is noninferior to treatment for 6 months.
Coorte retrospectiva | Asma em crianças e adolescentes não está associada a risco aumentado de infecção por SARS-CoV-2.
15 Mar, 2022 | 13:17hAsthma and the Risk of SARS-CoV-2 Infection Among Children and Adolescents – Pediatrics
Comentário: Kids with asthma not at higher risk of COVID-19, study finds – CIDRAP
Conteúdos relacionados:
We expected people with asthma to fare worse during COVID. Turns out they’ve had a break.
Asthma in COVID-19 hospitalizations: An overestimated risk factor?
Estudo randomizado aberto | Azitromicina para asma mal controlada em crianças.
15 Mar, 2022 | 13:09hAzithromycin for Poorly Controlled Asthma in Children: A randomized controlled trial – CHEST (link para o resumo – $ para o texto completo)
Comentário: Adding azithromycin to standard care improves asthma control, exacerbations in children – Healio
Conteúdo relacionado: Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma
Estudo randomizado | Em crianças com tuberculose não grave e suscetível a medicamentos, o tratamento por 4 meses é não inferior ao tratamento por 6 meses.
10 Mar, 2022 | 15:59hComunicado de imprensa: Treatment length reduced for children with tuberculosis – University College London
Comentário no Twitter
Completing 6 months of treatment for tuberculosis in children is a challenge. In this open-label trial involving 1204 children in sub-Saharan Africa and India, 4 months of antituberculosis therapy was noninferior to 6 months of therapy. https://t.co/zkD4URWMru pic.twitter.com/LFR6ZzTKgs
— NEJM (@NEJM) March 9, 2022
Associação de insuficiência respiratória na primeira infância com desfechos neurocognitivos de longo prazo.
9 Mar, 2022 | 13:33hAssociation of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes – JAMA (link para o resumo – $ para o texto completo)
Comentários:
IQ Lower for Survivors of PICU Respiratory Failure Hospitalization – HealthDay
Estudo randomizado | Azitromicina não é efetiva na prevenção de sibilo recorrente após bronquiolite grave causada por vírus sincicial respiratório.
8 Mar, 2022 | 18:40hComentários:
Comentário no Twitter
This RCT tested oral azithromycin vs placebo to reduce recurrent wheeze (RW) in 1-18-month-olds hospitalized with acute severe RSV bronchiolitis. Azithromycin did not reduce occurrence of RW and may increase risk of RW in some groups. #AAAAI22 #Asthma #EBM https://t.co/jYcBuiQ8aY pic.twitter.com/u65NbQaIlX
— NEJM Evidence (@NEJMEvidence) February 28, 2022