Acesso livre
Acesso livre

Pediatria

Ponto de vista | Vacinas contra COVID-19 na pediatria: o que pais, médicos e formadores de políticas públicas precisam saber.

8 Nov, 2021 | 12:43h

Pediatric COVID-19 Vaccines: What Parents, Practitioners, and Policy Makers Need to Know – JAMA

Ponto de vista | Crianças e COVID-19 nas escolas.

8 Nov, 2021 | 12:38h

Children and COVID-19 in schools – Science

Conteúdos relacionados:

Instead of quarantine for Covid-exposed students, some schools are trying test-to-stay.

Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

Kids are losing school days to quarantines. Here’s a way to keep them in classrooms – “Test-to-stay could dramatically reduce close contact quarantines”.

Opinion | Data from routine Covid testing can help schools stay open this year.

CDC Report: Schools without mask requirements were more likely to have Covid-19 outbreaks.

Perspective | Schools have begun mass testing for COVID-19. But hurdles and uncertainties remain.

COVID and schools: the evidence for reopening safely.

COVID studies note online learning stress, fewer cases in schools with protocols

Dez coisas a saber sobre a síndrome inflamatória multissistêmica em crianças (multisystem inflammatory syndrome in children – MIS-C).

4 Nov, 2021 | 12:01h

Ten Things to Know About MIS-C – American College of Cardiology

Conteúdos relacionados:

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

Programa nacional de vacinação contra HPV na Inglaterra foi associado com uma redução estimada de 87% nas taxas de câncer do colo do útero naquelas que receberam a vacina entre 12-13 anos de idade.

4 Nov, 2021 | 11:59h

The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence: a register-based observational study – The Lancet

Conteúdos relacionados:

Nationwide cohort study in Sweden shows HPV vaccination linked to reduced risk of invasive cervical cancer

CDC: 92% of Human Papillomavirus–Attributable Cancers can be Targeted by HPV Vaccination

Meta-Analysis: Population-level Impact of HPV Vaccination Programs

 

Comentário no Twitter

 

Conselho do CDC endossa a vacina da Pfizer contra Covid-19 para crianças de 5 a 11 anos.

3 Nov, 2021 | 11:18h

Slides da apresentação do ACIP: November 2-3, 2021 Meeting – Centers for Disease Control and Prevention

Comentários:

CDC advisors give go-ahead to COVID-19 vaccines for young kids – CIDRAP

CDC advisers endorse Pfizer’s Covid-19 vaccine for kids 5-11 – STAT

American Academy of Pediatrics Applauds CDC Advisory Committee’s Approval of Safe, Effective COVID-19 Vaccine for Children Ages 5-11

Entre os adolescentes, o tempo de diversão em telas dobrou durante a pandemia, afetando sua saúde mental.

3 Nov, 2021 | 11:14h

Comunicado de imprensa: Adolescents’ recreational screen time doubled during pandemic, affecting mental health – University of California, San Francisco

Estudo original: Screen Time Use Among US Adolescents During the COVID-19 Pandemic: Findings From the Adolescent Brain Cognitive Development (ABCD) Study – JAMA Pediatrics

Comentário: Kids nearly doubled screen time during the pandemic, but there is something you can do about it – CNN

 

Comentário do autor no Twitter

 

Diretriz da AAP | Prevenção aos erros de administração de medicamentos em casa.

3 Nov, 2021 | 11:07h

Preventing Home Medication Administration Errors – Pediatrics

Comentário: Ways to Prevent Children’s Medication Errors at Home – American Academy of Pediatrics

 

Comentário no Twitter

 

Estudo randomizado | Entre crianças com pneumonia adquirida na comunidade que receberam alta hospitalar ou do departamento de emergência dentro de 48 horas, uma dose menor de amoxicilina oral foi não inferior a uma dose maior, e o tratamento por 3 dias foi não inferior ao curso de 7 dias.

3 Nov, 2021 | 11:05h

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA (gratuito por tempo limitado)

Conteúdos relacionados:

ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections

RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.

RCT: A Seven-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales was noninferior to a 14-days course.

RCT: Among patients with prosthetic joint infection, antibiotic therapy for 6 weeks was NOT shown to be noninferior to antibiotic therapy for 12 weeks and resulted in a higher percentage of patients with unfavorable outcomes.

Randomized Trial: Seven vs. Fourteen Days of Antibiotic Therapy for Uncomplicated Gram-negative Bacteremia

 

Comentário no Twitter

 

Mortes associadas a COVID-19 e síndrome inflamatória multissistêmica em crianças (multisystem inflammatory syndrome – MIS-C) entre crianças e adolescentes nos Estados Unidos.

2 Nov, 2021 | 12:31h

Deaths in Children and Adolescents Associated With COVID-19 and MIS-C in the United States – Pediatrics

Conteúdos relacionados:

Thirty-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – “Despite negligible fatality, complications including hospitalization, hypoxemia, and pneumonia were more frequent in children and adolescents with COVID-19 than with influenza”.

Deaths from COVID ‘incredibly rare’ among children.

[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.

Dois estudos observacionais levantam dúvidas sobre os efeitos do fechamento de escolas na redução da transmissão da Covid-19.

28 Out, 2021 | 16:15h

Estudo 1: No causal effect of school closures in Japan on the spread of COVID-19 in spring 2020 – Nature Medicine

Estudo 2: The impact of school opening model on SARS-CoV-2 community incidence and mortality – Nature Medicine

 

Comentários no Twitter

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