Otorrinolaringologia/Cabeça e Pescoço

M-A | Taxas de complicações da tireoidectomia total vs. hemitireoidectomia no tratamento do microcarcinoma papilar de tireoide.

12 Mai, 2022 | 15:02h

Complication Rates of Total Thyroidectomy vs Hemithyroidectomy for Treatment of Papillary Thyroid Microcarcinoma: A Systematic Review and Meta-analysis – JAMA Otolaryngology-Head & Neck Surgery (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

In this systematic review and #meta-analysis, complications in the surgical management of micropapillary #thyroid carcinoma increased with the extent of surgery performed, although complications and recurrence were low for both operations. https://t.co/Itf14o38Vu @wiscsurgery

— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) May 6, 2022

 

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Atualização de diretriz de prática clínica ESMO sobre o uso de terapia sistêmica no câncer de tireoide avançado.

6 Mai, 2022 | 17:32h

ESMO Clinical Practice Guideline update on the use of systemic therapy in advanced thyroid cancer – Annals of Oncology

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Resultados de 10 anos de um estudo randomizado | Efeitos da paratireoidectomia vs. observação sobre a morbidade e a mortalidade de pacientes com hiperparatireoidismo primário leve.

3 Mai, 2022 | 15:50h

Mortality and Morbidity in Mild Primary Hyperparathyroidism: Results From a 10-Year Prospective Randomized Controlled Trial of Parathyroidectomy Versus Observation – Annals of Internal Medicine (link para o resumo – $ para o texto completo)

Comentário: Parathyroidectomy No Better for Mild Primary Hyperparathyroidism – HealthDay

 

Comentário no Twitter

#ICYMI: new RCT from @UniOslo found early surgery does not appear to reduce negative outcomes for healthy patients with primary #hyperparathyroidism: https://t.co/RnWadklja2 pic.twitter.com/vuS4xSt128

— Annals of Int Med (@AnnalsofIM) April 25, 2022

 

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Por que a variante Ômicron geralmente não acomete a função olfatória? Implicações para a patogênese da anosmia na COVID-19.

27 Abr, 2022 | 16:25h

Why does the Omicron Variant Largely Spare Olfactory Function? Implications for the Pathogenesis of Anosmia in COVID-19 – The Journal of Infectious Diseases

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Estudo randomizado | Sintilimabe vs. placebo em combinação com quimioterapia como tratamento de primeira linha para carcinoma esofágico de células escamosas metastático ou localmente avançado.

21 Abr, 2022 | 12:13h

Sintilimab versus placebo in combination with chemotherapy as first line treatment for locally advanced or metastatic oesophageal squamous cell carcinoma (ORIENT-15): multicentre, randomised, double blind, phase 3 trial – The BMJ

 

Comentário no Twitter

Compared with placebo, sintilimab in combination with chemo showed significant benefits in overall survival and progression free survival as first line treatment in patients with advanced or metastatic oesophageal squamous cell carcinoma, finds study https://t.co/m8Gn3SBmCu

— The BMJ (@bmj_latest) April 19, 2022

 

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Desenvolvimento e validação de modelos de aprendizado de máquina (machine learning) para prever metástases nodais ocultas no carcinoma de células escamosas da cavidade oral em estágio inicial.

21 Abr, 2022 | 12:01h

Development and Validation of Machine Learning Models for Predicting Occult Nodal Metastasis in Early-Stage Oral Cavity Squamous Cell Carcinoma – JAMA Network Open

 

Comentário no Twitter

In this diagnostic modeling study, #MachineLearning models built with multi-institutional data showed potential to reduce morbidity from elective neck dissections with similar cancer outcomes in patients with early-stage oral cavity squamous cell carcinoma https://t.co/aRktgc0ms6

— JAMA Network Open (@JAMANetworkOpen) April 13, 2022

 

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M-A de estudos randomizados | Monitoramento intraoperatório recorrente do nervo laríngeo vs. visualização isolada.

20 Abr, 2022 | 14:48h

Intraoperative recurrent laryngeal nerve monitoring versus visualisation alone – A systematic review and meta-analysis of randomized controlled trials – American Journal of Surgery

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Um estudo randomizado controlado explorou a segurança e a tolerabilidade do sultiame na apneia do sono.

19 Abr, 2022 | 12:28h

A Randomized Controlled Trial Exploring Safety and Tolerability of Sulthiame in Sleep Apnea – American Journal of Respiratory and Critical Care Medicine

Comunicado de imprensa: Drug reduced frequency of breathing pauses in sleep apnea – University of Gothenburg

 

Comentário no Twitter

In a four-week trial of patients with OSA not tolerating PAP therapy, researchers found that the carbonic anhydrase inhibitor sulthiame reduced OSA by more than 20 events per hour, one of the strongest reductions reported in a drug trial in OSA. https://t.co/EizlbFbvFm pic.twitter.com/DxylRQR4Pa

— American Academy of Sleep Medicine (@AASMorg) February 28, 2022

 

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Estudo transversal | Avaliação de modelos preditivos de apneia do sono a partir da gravação, em smartphone, dos sons respiratórios durante o sono.

19 Abr, 2022 | 12:15h

Evaluating Prediction Models of Sleep Apnea From Smartphone-Recorded Sleep Breathing Sounds – JAMA Otolaryngology-Head & Neck Surgery (link para o resumo – para o texto completo)

 

Comentário no Twitter

Study found, smartphone-recorded #sleep breathing sounds may be used to create prediction models for obstructive sleep apnea, but additional verification of real-life recordings using various smartphone devices should be conducted. #OSA https://t.co/3ESRYefsyj

— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) April 14, 2022

 

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Desenvolvimento e validação de um modelo de decisão analítica para vigilância pós-tratamento de pacientes com carcinoma orofaríngeo.

18 Abr, 2022 | 14:55h

Development and Validation of a Decision Analytical Model for Posttreatment Surveillance for Patients With Oropharyngeal Carcinoma – JAMA Network Open

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