Oncologia

Estudo randomizado de não inferioridade mostrou que a radioterapia pode ser seguramente omitida em muitas crianças e adolescentes em estágios intermediário e avançado de linfoma de Hodgkin clássico.

10 Dez, 2021 | 11:06h

Response-adapted omission of radiotherapy and comparison of consolidation chemotherapy in children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma (EuroNet-PHL-C1): a titration study with an open-label, embedded, multinational, non-inferiority, randomised controlled trial – The Lancet Oncology

 

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Revisão sistemática | Benefícios e prejuízos do rastreamento mamográfico anual, bienal e trienal para mulheres na média de risco para câncer de mama.

9 Dez, 2021 | 15:20h

Benefits and harms of annual, biennial, or triennial breast cancer mammography screening for women at average risk of breast cancer: a systematic review for the European Commission Initiative on Breast Cancer (ECIBC) – British Journal of Cancer

 

Comentário no Twitter (fio – clique para saber mais)

Our comprehensive #systematicreview for the #ECIBC on intervals (every 1, 2, 3 years) of #breastcancer #screening is available.
We included RCT, observational, and mathematical modeling studies to assess benefits and harms and applied the #GRADE approachhttps://t.co/IfplsWfKuA pic.twitter.com/7niEbnaWKR

— Carlos Canelo-Aybar (@ccaneloa) November 27, 2021

 

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M-A | Eficácia e segurança associadas a inibidores do checkpoint imunológico no carcinoma hepatocelular irressecável.

8 Dez, 2021 | 12:58h

Efficacy and Safety Associated With Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma: A Meta-analysis – JAMA Network Open

 

Comentário no Twitter

This meta-analysis of RCTs shows immune checkpoint inhibitors are associated with demonstrated the superior efficacy and safety of versus standard systemic therapies in patients with unresectable hepatocellular carcinoma. https://t.co/fJdFng69qH

— JAMA Network Open (@JAMANetworkOpen) December 6, 2021

 

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Mesotelioma pleural maligno: Diretrizes de Prática Clínica da ESMO para diagnóstico, tratamento e seguimento.

8 Dez, 2021 | 12:57h

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

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Atualização das Diretrizes de Prática Clínica da ESMO para uso de imunoterapia no estágio inicial ou avançado do carcinoma de células renais.

8 Dez, 2021 | 12:56h

ESMO Clinical Practice Guideline update on the use of immunotherapy in early stage and advanced renal cell carcinoma – Annals of Oncology

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Farmacologia clínica de medicamentos citotóxicos em neonatos e crianças: orientação de doses baseada em evidências.

7 Dez, 2021 | 11:34h

Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance – European Journal of Cancer

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Revisão | Passado, presente e futuro da cardiotoxicidade induzida por radiação.

6 Dez, 2021 | 16:13h

Past, Present, and Future of Radiation-Induced Cardiotoxicity: Refinements in Targeting, Surveillance, and Risk Stratification – JACC: CardioOncology

Vídeo: Radiation Therapy and Cardiovascular Disease | JACC: CardioOncology Author Discussion

Conteúdos relacionados:

Cohort Study: Women treated with radiation therapy for left-sided breast cancer had over twice the risk of subsequent coronary artery disease compared with women treated with radiation therapy for right-sided breast cancer.

Radiation‐induced cardiovascular disease: review of an underrecognized pathology.

Short review: How to diagnose and manage radiation therapy cardiotoxicity

Cohort Study: Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients with Lung Cancer

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O impacto global do câncer em adolescentes e jovens adultos em 2019: análise sistemática para o Global Burden of Disease Study 2019.

6 Dez, 2021 | 16:02h

The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet Oncology

Comentário convidado: Burden of cancer in adolescents and young adults – The Lancet Oncology

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Estudo randomizado | Desfechos de longo prazo com nivolumabe associado a ipilimumabe ou nivolumabe isolado vs. ipilimumabe em pacientes com melanoma avançado.

6 Dez, 2021 | 15:51h

Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma – Journal of Clinical Oncology

Editorial: CheckMate-067: Raising the Bar for the Next Decade in Oncology – Journal of Clinical Oncology

Estudo original: #ESMO19 – Randomized Trial: Improved Overall Survival at 5 Years with Combined Immunotherapy for Advanced Melanoma

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Estudo randomizado | Cirurgia citorredutora para recidiva de câncer de ovário.

2 Dez, 2021 | 11:19h

Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer – New England Journal of Medicine

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