Oncologia

Assinaturas genéticas no câncer hepatobiliar.

14 Mar, 2022 | 13:25h

Mutational signatures and processes in hepatobiliary cancers – Nature Reviews Gastroenterology & Hepatology (se o acesso a este link for pago, tente este)

 

Comentário no Twitter

Appeared online this week in @NatRevGastroHep 🧵
"Mutational signatures and processes in hepatobiliary cancers" a #Review article
Read here 👉🏾https://t.co/fUcaZ81BSA
Attached Figure: a clinicopathological and molecular overview of hepatobiliary cancers pic.twitter.com/d6MVAFu0J1

— Nature Reviews Gastroenterology & Hepatology (@NatRevGastroHep) March 11, 2022

 

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Estudo randomizado | Metotrexato em dose densa, vimblastina, doxorrubicina e cisplatina ou gencitabina e cisplatina como quimioterapia perioperatória para pacientes com câncer de bexiga com invasão muscular não metastático.

14 Mar, 2022 | 13:23h

Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin or Gemcitabine and Cisplatin as Perioperative Chemotherapy for Patients With Nonmetastatic Muscle-Invasive Bladder Cancer: Results of the GETUG-AFU V05 VESPER Trial – Journal of Clinical Oncology

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Atualização da diretriz ASCO de recomendações estratificadas por disponibilidade de recursos | Tratamento de cuidado de pacientes com câncer de colo do útero invasivo.

14 Mar, 2022 | 13:22h

Management and Care of Patients With Invasive Cervical Cancer: ASCO Resource-Stratified Guideline Rapid Recommendation Update – JCO Global Oncology

Comunicado de imprensa: ASCO Guideline Recommends Addition of Monoclonal Antibody to Invasive Cervical Cancer Management – ASCO Daily News

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Estudo randomizado | Sobrevida geral do câncer de mama avançado com ribociclibe e letrozol.

11 Mar, 2022 | 14:56h

Overall Survival with Ribociclib plus Letrozole in Advanced Breast Cancer – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentários:

Ribociclib plus endocrine therapy offers survival benefit for postmenopausal patients with metastatic breast cancer – University of Texas MD Anderson Cancer Center / News Medical

Adding Ribociclib to Letrozole Prolongs Survival in Advanced Breast Cancer – HealthDay

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Revisão | Indicações cirúrgicas atuais para câncer pulmonar de não pequenas células.

11 Mar, 2022 | 14:35h

Current Surgical Indications for Non-Small-Cell Lung Cancer – Cancers

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Estudo randomizado | Em pacientes com câncer de tireoide de baixo risco, a tireoidectomia sem ablação por radioiodo foi não inferior à tireoidectomia com ablação por radioiodo em 3 anos.

10 Mar, 2022 | 15:57h

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentário: New research casts doubt on a cornerstone of thyroid cancer treatment – STAT

 

Comentário no Twitter

In RCT involving patients with low-risk differentiated thyroid cancer undergoing thyroidectomy, a follow-up strategy that did not involve the use of radioiodine was noninferior to the use of radioiodine in the response to treatment at 3 years. https://t.co/RaJL3tdE4T pic.twitter.com/8nIPw50nkg

— NEJM (@NEJM) March 9, 2022

 

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Recomendações de consenso do GEC ESTRO ACROP para a braquiterapia de contato no câncer retal.

10 Mar, 2022 | 15:39h

GEC ESTRO ACROP consensus recommendations for contact brachytherapy for rectal cancer – Clinical and Translational Radiation Oncology

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Viabilidade da alta hospitalar em 72 horas após grande cirurgia colorretal: lições aprendidas após 5 anos de experiência institucional com o protocolo ERAS.

10 Mar, 2022 | 15:27h

Feasibility of discharge within 72 hours of major colorectal surgery: lessons learned after 5 years of institutional experience with the ERAS protocol – BJS Open

Conteúdos relacionados:

ERAS Guidelines for Perioperative Care in Elective Colorectal Surgery

Review: Enhanced Recovery After Surgery in Emergency Colorectal Surgery

Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons

 

Comentário no Twitter

A five year #retrospective #cohort study explored link between early post-op discharge and #ERAS (n=965)

-> adherence to >80% ERAS components associated with early discharge. Long operations, drains, and complications assoc w/longer stays.https://t.co/2nXBrKbg5D#SoMe4Surgery pic.twitter.com/h5P4YFC8zh

— BJS Open (@BjsOpen) March 2, 2022

 

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Estudo randomizado | Dor e qualidade de vida relacionada à saúde com olaparibe vs. escolha médica de medicamentos hormonais de próxima geração em pacientes com câncer de próstata metastático e resistente à castração com alterações homólogas nos genes de reparação e recombinação.

10 Mar, 2022 | 15:24h

Pain and health-related quality of life with olaparib versus physician’s choice of next-generation hormonal drug in patients with metastatic castration-resistant prostate cancer with homologous recombination repair gene alterations (PROfound): an open-label, randomised, phase 3 trial – The Lancet Oncology (link para o resumo – $ para o texto completo)

Comentário: Pain and Quality of Life in the PROfound Trial: Olaparib vs Next-Generation Hormonal Agent in Metastatic Castration-Resistant Prostate Cancer With HRR Gene Alterations – The ASCO Post

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Mapeamento de revisões sistemáticas sobre intervenções na sobrevida do câncer de mama.

10 Mar, 2022 | 15:22h

Mapping Systematic Reviews of Breast Cancer Survivorship Interventions: A Network Analysis – Journal of Clinical Oncology

 

Comentário no Twitter

🌐 Despite vast volume, review-level #BreastCancer #survivorship research is unevenly distributed and siloed. Strategic planning of future research, in consultation with survivors, is needed. ➡️ https://t.co/pxMp5XK8B8 #JCO #BCSM @EmmaBKemp1 #survonc pic.twitter.com/TRjOEJQbrw

— Journal of Clinical Oncology (@JCO_ASCO) March 5, 2022

 

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