Oncologia

Estudo randomizado | Pembrolizumabe vs. placebo como terapia adjuvante no melanoma estágio IIB ou IIC completamente ressecado.

5 Abr, 2022 | 11:56h

Pembrolizumab versus placebo as adjuvant therapy in completely resected stage IIB or IIC melanoma (KEYNOTE-716): a randomised, double-blind, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)

Estudo antes-e-depois | Gestão de antibióticos em pacientes com neutropenia febril de alto risco reduziu o uso de carbapenêmicos e glicopeptídios e foi associada com melhores desfechos clínicos.

5 Abr, 2022 | 11:52h

Antimicrobial stewardship in high-risk febrile neutropenia patients – Antimicrobial Resistance & Infection Control

Conteúdos relacionados:

Safety and efficacy of antibiotic de-escalation and discontinuation in high-risk hematological patients with febrile neutropenia: a single-center experience.

Management of febrile neutropaenia: ESMO Clinical Practice Guidelines – Annals of Oncology

Comentário do autor no Twitter (fio – clique para saber mais)

📢 Our new study "Antimicrobial stewardship in high-risk febrile neutropenia patients." is now out in #ARIC !💥

Find our open access paper here: https://t.co/2fFoHfpEzi

And some data bellow ⬇️ (1/10) pic.twitter.com/kg4pYQs9HD

— Adrien Contejean (@AdrienContejean) March 29, 2022

Relatório ósseo e sistema de dados (Bone-RADS) | Diretrizes para diagnóstico incidental de lesões ósseas isoladas em TC e RM em adultos.

5 Abr, 2022 | 11:49h

Society of Skeletal Radiology– white paper. Guidelines for the diagnostic management of incidental solitary bone lesions on CT and MRI in adults: bone reporting and data system (Bone-RADS) – Skeletal Radiology

Comentário no Twitter (artigo e imagens sob http://creativecommons.org/licenses/by-nc/4.0/)

Bone RADS- White Paper from @SkeletalRadiol
Want to know how to handle bone lesions? Take a look – open access:https://t.co/mBUFzgJiCf @cychang1414 @ahlawat_shivani @HillaryGarnerMD @mbucknor @Radsdoc82 @behrangamini @IKhodarahmi @JimWuMSK
Apologies couldn't find all authors pic.twitter.com/hL8r04uK40

— Adam Singer, MD (@AdamSingerMD) April 1, 2022

Estudo mostra que não há risco aumentado de tumores cerebrais em usuários de telefones celulares.

1 Abr, 2022 | 13:16h

Comunicado de imprensa: No increased risk of brain tumours for mobile phone users, new study finds – University of Oxford

Estudo original: Cellular Telephone Use and the Risk of Brain Tumors: Update of the UK Million Women Study – JNCI: Journal of the National Cancer Institute

Seguimento de longo prazo de estudo randomizado | Nivolumabe com quimioterapia ou ipilimumabe no câncer gastroesofágico.

1 Abr, 2022 | 12:52h

Nivolumab plus chemotherapy or ipilimumab in gastro-oesophageal cancer – Nature

Estudo original: RCT: First-line nivolumab plus chemotherapy vs. chemotherapy alone for advanced gastric, gastro-esophageal junction, and esophageal adenocarcinoma.

Comentário no Twitter

New data from CheckMate 649 confirm that the OS benefit of nivolumab added to chemotherapy for advanced-stage gastroesophageal adenocarcinoma persists beyond 24 mo (HR 0.79; 95% CI 0.71-0.88); however, nivo+ipi did not improve OS vs chemotherapy alone: https://t.co/2Pom4zD7oX

— NatureRevClinOncol (@NatRevClinOncol) March 25, 2022

Recomendações de diretriz baseada em evidência para o uso da ressonância magnética no diagnóstico de câncer de próstata clinicamente significante.

1 Abr, 2022 | 12:48h

Evidence-based guideline recommendations on multiparametric magnetic resonance imaging in the diagnosis of clinically significant prostate cancer: A Cancer Care Ontario updated clinical practice guideline – Canadian Urological Association Journal

Revisão prática | Tratamento efetivo e baseado em evidências para a fadiga em pacientes com câncer avançado.

1 Abr, 2022 | 12:45h

Practice review: Evidence-based and effective management of fatigue in patients with advanced cancer – Palliative Medicine

Revisão prática | Tratamento efetivo e baseado em evidências para a anemia em pacientes sob cuidados paliativos.

1 Abr, 2022 | 12:44h

Practice review: Evidence-based and effective management of anaemia in palliative care patients – Palliative Medicine

Revisão | Uso de atendimento virtual em pacientes com malignidades hematológicas.

1 Abr, 2022 | 12:41h

The Use of Virtual Care in Patients with Hematologic Malignancies: A Scoping Review – Current Oncology

Comentário de estudo | Idosas com câncer de mama escolhem tratamentos menos agressivos quando usam ferramenta de auxílio à decisão.

1 Abr, 2022 | 12:40h

Older women with breast cancer chose less aggressive treatment when they used a decision aid – National Institute for Health Research

Estudo original: Bridging the age gap in breast cancer: cluster randomized trial of two decision support interventions for older women with operable breast cancer on quality of life, survival, decision quality, and treatment choices – British Journal of Surgery