Oncologia
Estudo de braço único fase 2 | Atividade do cabazitaxel no lipossarcoma dediferenciado localmente avançado metastático ou inoperável.
23 Ago, 2022 | 16:31hActivity of Cabazitaxel in Metastatic or Inoperable Locally Advanced Dedifferentiated Liposarcoma: A Phase 2 Study of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) – JAMA Oncology (gratuito por tempo limitado)
Comentário convidado: Optimizing Histology-Specific Clinical Trials in Soft-Tissue Sarcoma—Are We There Yet? – JAMA Oncology (gratuito por tempo limitado)
Estudo | Quase metade das mortes globais por câncer se devem a fatores de risco, sendo tabagismo, uso de álcool e IMC alto os que mais contribuem.
23 Ago, 2022 | 16:28hComunicado de imprensa: The Lancet: Almost half of global cancer deaths are due to risk factors, with smoking, alcohol use, and high BMI the greatest contributors – Institute for Health Metrics and Evaluation
Comentário no Twitter (fio – clique para saber mais)
NEW #GBDstudy research from 2010-2019 found that a majority of attributable #Cancer DALYs globally were from behavioral risk factors. The top 3 behavioral risk factors for cancer burden were: #smoking 🚬, #alcohol 🍺, & high #BMI. @TheLancet »https://t.co/qPzDKzfLda pic.twitter.com/LnkvlkDHgA
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) August 18, 2022
Análise agrupada de doença pulmonar intersticial relacionada a medicamentos e/ou pneumonite em 9 estudos de monoterapia com trastuzumabe deruxtecano.
22 Ago, 2022 | 16:34hComentários:
Trastuzumab deruxtecan-related ILD/pneumonitis characterized – medwire News
Conteúdo relacionado: Trastuzumab Deruxtecan-Induced Interstitial Lung Disease/Pneumonitis in ERBB2-Positive Advanced Solid Malignancies: A Systematic Review – Drugs
Revisão | Esôfago de Barrett.
22 Ago, 2022 | 16:06hBarrett Esophagus: A Review – JAMA (gratuito por tempo limitado)
Revisão clínica em áudio: Barrett Esophagus – JAMA
Conteúdo relacionado: Diagnosis and Management of Barrett’s Esophagus: An Updated ACG Guideline – American Journal of Gastroenterology
Atualização de diretriz ASCO | Quimioterapia e terapia-alvo para câncer de mama metastático negativo para receptor 2 do fator de crescimento epidérmico humano, seja com pré-tratamento endocrinológico ou negativo para receptor hormonal.
22 Ago, 2022 | 15:59h
Falando sobre morrer: conversas melhores no fim da vida.
22 Ago, 2022 | 15:57hTalking about dying: better conversations at the end of life – Evidently Cochrane
Revisões originais:
Comentário no Twitter
New @CochraneUK blog: @SarahChapman30 reflects on text conversations she had with her Mum’s carer when her Mum was dying during lockdown & explores recent evidence on good communication between health professionals, those who are dying & their families: https://t.co/WzA1Ff8jdF pic.twitter.com/fSlRyEOVym
— The Cochrane Library (@CochraneLibrary) August 16, 2022
Revisão sistemática | Status menopausal, ultrassonografia e testes com biomarcadores em combinação para diagnóstico de câncer de ovário em mulheres sintomáticas.
22 Ago, 2022 | 15:55h
M-A | Associação entre imunoterápicos anticâncer e desfechos relatados pelos pacientes e avaliados em estudos clínicos randomizados.
22 Ago, 2022 | 15:51h
Comentário no Twitter
Immunotherapy was associated with improved the quality of life of patients with advanced cancer, according to results of this comprehensive meta-analysis and systematic review of 34 RCTs of immune checkpoint inhibitors. https://t.co/uSLFT3Nuww
— JAMA Network Open (@JAMANetworkOpen) August 16, 2022
M-A | Extensão da ressecção tumoral e sobrevida em pacientes pediátricos com gliomas de alto grau.
22 Ago, 2022 | 15:18h
Comentário no Twitter
In this systematic review and meta-analysis of pediatric high-grade gliomas, gross total resection was associated with better overall survival than subtotal resection and biopsy. https://t.co/QpKiDKpYYs
— JAMA Network Open (@JAMANetworkOpen) August 16, 2022
Estudo randomizado | TC torácica com radiografia vs. radiografia torácica para seguimento de câncer de pulmão de não pequenas células completamente ressecado.
22 Ago, 2022 | 14:56hChest CT scan plus x-ray versus chest x-ray for the follow-up of completely resected non-small-cell lung cancer (IFCT-0302): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link para o resumo – $ para o texto completo)
Comentário no Twitter (fio – clique para saber mais)
Totally unexpected! After resection of early NSCLC in 1775 pts, follow-up by ct-scan did not improve survival vs a simple chest X-Rays! We should ALWAYS questioned our practice. Amazing work from Virginie Westeel @barlesi @IFCTlung https://t.co/iMFGtpkQcF
— Benjamin Besse (@BenjaminBesseMD) August 12, 2022