Onco-hematologia

Recomendações de melhores práticas | Tratamento de crianças e adultos em terapia com células CAR T.

13 Jan, 2022 | 11:34h

Management of Adults and Children receiving CAR T-cell therapy: 2021 Best Practice Recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA) – Annals of Oncology

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Programa educacional da ASH | Hematology – Séries de artigos de revisão com casos clínicos publicados anualmente pela American Society of Hematology.

13 Dez, 2021 | 11:23h

Página principal: Hematology, the ASH Education Program

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Estudo randomizado de não inferioridade mostrou que a radioterapia pode ser seguramente omitida em muitas crianças e adolescentes em estágios intermediário e avançado de linfoma de Hodgkin clássico.

10 Dez, 2021 | 11:06h

Response-adapted omission of radiotherapy and comparison of consolidation chemotherapy in children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma (EuroNet-PHL-C1): a titration study with an open-label, embedded, multinational, non-inferiority, randomised controlled trial – The Lancet Oncology

 

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Estudo randomizado | Maribavir para infecções por citomegalovírus refratárias com ou sem resistência pós-transplante.

7 Dez, 2021 | 11:29h

Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results from a Phase 3 Randomized Clinical Trial – Clinical Infectious Diseases

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Revisão | Doença de Castleman.

26 Nov, 2021 | 11:44h

Castleman disease – Nature Reviews Disease Primers (se o acesso a este link for pago, tente este)

Infográfico: Castleman Disease (se o acesso a este link for pago, tente este)

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Avaliação do trióxido arsênico e do ácido retinoico all-trans para o tratamento da leucemia promielocítica aguda pediátrica.

15 Nov, 2021 | 13:34h

Assessment of Arsenic Trioxide and All-trans Retinoic Acid for the Treatment of Pediatric Acute Promyelocytic Leukemia: A Report From the Children’s Oncology Group AAML1331 Trial – JAMA Oncology

Comunicado de imprensa: Drug combination helps children with acute promyelocytic leukemia avoid conventional chemotherapy – NIH News Releases

 

Comentário no Twitter

Clinical trial showed that pediatric patients with acute promyelocytic leukemia (APL) have very high cure rates with treatment regimen that uses targeted therapy and no cytotoxic chemotherapy for standard risk APL or limited anthracycline for high risk APL https://t.co/V3mahhIb6Y

— JAMA Oncology (@JAMAOnc) November 11, 2021

 

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Estudo randomizado por cluster | Em idosos com câncer avançado, um programa de avaliação geriátrica reduziu os efeitos tóxicos do tratamento.

5 Nov, 2021 | 17:09h

Evaluation of geriatric assessment and management on the toxic effects of cancer treatment (GAP70+): a cluster-randomised study – The Lancet

Comunicado de imprensa: Less Chemotherapy, Personalized Care: Wilmot Study Reinforces Major Strides in Geriatric Oncology – University of Rochester Medical Center

Conteúdos relacionados:

RCT: A geriatric assessment–driven intervention can reduce chemotherapy-related toxic effects in older adults with cancer.

Perspective: A Cancer Care Approach Tailored to The Elderly May Have Better Results

 

Comentário da autora no Twitter (fio – clique para saber mais)

I’m proud of this @mycarg @WilmotCancer effort published online @TheLancet on the eve of @SIOGorg meeting—GA w/management lowers tox in #gerionc pts (RR 0.74, CI 0.64-0.84; p=0.0001). https://t.co/tr6zVXe6Jd

— Supriya Mohile (@rochgerionc) November 3, 2021

 

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Diretriz do CDC | Pessoas imunocomprometidas podem precisar de uma quarta dose de vacina contra Covid-19.

4 Nov, 2021 | 12:05h

Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States – Centers for Disease Control and Prevention

Comentários:

Immunocompromised may need a fourth Covid-19 shot, CDC says – CNN

Some immunocompromised people can receive a 4th Covid shot, CDC says – NBC News

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Atualização de Diretriz ASCO | Manejo de eventos adversos imunes relacionados a imunoterapia no tratamento do câncer.

2 Nov, 2021 | 12:25h

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: ASCO Guideline Update – Journal of Clinical Oncology

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Diretriz ASCO | Manejo de eventos adversos imunes em pacientes sob terapia com célula T do receptor de antígeno quimérico.

2 Nov, 2021 | 12:23h

Management of Immune-Related Adverse Events in Patients Treated With Chimeric Antigen Receptor T-Cell Therapy: ASCO Guideline – Journal of Clinical Oncology

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