Acesso livre
Acesso livre

Neurologia

Estudo randomizado de fase III sobre a irradiação cranial profilática (ICP) evitando-se ou não o hipocampo para câncer de pulmão de células pequenas (CPCP) – “Este estudo fornece a primeira evidência clínica de que evitar o hipocampo durante a ICP em pacientes com CPCP pode preservar a função cognitiva.”

13 Ago, 2021 | 12:05h

Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study – Journal of Clinical Oncology

M-A | Mais de 50 efeitos de longo prazo da COVID-19.

11 Ago, 2021 | 10:57h

More than 50 long-term effects of COVID-19: a systematic review and meta-analysis – Scientific Reports

Conteúdos relacionados:

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Cohort study: Risk factors for long covid in previously hospitalized children.

Viewpoint: The road to addressing Long Covid.

Review: Long covid—mechanisms, risk factors, and management.

Review: Symptoms, complications and management of long COVID.

Long Covid: fatigue, post-exertional malaise, and cognitive dysfunction are the most common symptoms, according to an international survey.

Studies elucidate poorly understood long COVID.

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Long Covid: 39% of patients report persistent symptoms more than seven months after diagnosis of COVID-19 in an outpatient setting.

[Preprint] Long Covid: Persistent symptoms following SARS-CoV-2 infection in a random community sample of 508,707 people.

Long COVID or post-acute sequelae of COVID-19 (PASC): An overview of biological factors that may contribute to persistent symptoms.

Long Covid: Half of young adults with COVID-19 have persistent symptoms 6 months after, study finds.

[Preprint] Long Covid: Third of people infected have long term symptoms.

Opinion | Causation or confounding: why controls are critical for characterizing long COVID – “Many of the self-reported symptoms, such as intermittent headaches or tiredness, are nonspecific and prevalent in the general population”.

Almost 25% of COVID-19 patients develop long-lasting symptoms, according to a new report.

Perspective | The four most urgent questions about long COVID.

Systematic review: Frequency, signs and symptoms, and criteria adopted for long COVID-19.

Report: 376,000 people in UK have had long Covid symptoms for at least a year.

Systematic review of 45 studies including 9751 participants, most of which were hospitalized, found 73% had at least 1 persistent symptom for weeks after Covid-19.

COVID Morbidity – The emerging burden of long COVID is significant, and needs to be considered when evaluating the risk vs. benefit of pandemic measures.

One year after hospital discharge due to SARS-CoV-2 Infection, the prevalence of long-term cough, chest pain, dyspnea, and fatigue was 2.5%, 6.5%, 23.3%, and 61.2%, respectively

Population-based cohort study: Non-hospitalized COVID-19 patients have low-risk of serious long-term effects, but visits to general practitioners and outpatient hospital visits are increased.

One third of patients hospitalized with COVID-19 have lung changes after a year

Long Covid: Largest post-acute COVID-19 study to date examined the health outcomes in more than 73,000 people who’d had COVID-19 and were not hospitalized

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Perspective | They Tested Negative for Covid. Still, They Have Long Covid Symptoms.

Large study finds 1 in 3 Covid-19 survivors have subsequent mental health and neurological conditions

Cohort study: One in ten have long-term effects 8 months following mild COVID-19

Long Covid Implications for the workplace

Long Covid in the UK – More than a million affected in February, survey suggests

Covid-19: Middle aged women face greater risk of debilitating long term symptoms

Persistent neurologic symptoms and cognitive dysfunction in non‐hospitalized Covid‐19 “long haulers”

Opinion | We need to start thinking more critically — and speaking more cautiously — about long Covid

Review | Post-acute COVID-19 syndrome

Long Covid | Four-month clinical status of a cohort of patients after hospitalization for COVID-19

Perspective | Long Covid isn’t as unique as we thought

Attributes and predictors of long COVID

WHO Report: Preparing for Long COVID 2021

Long Covid: Sequelae in adults at 6 Months after COVID-19 infection

How many people get ‘long COVID’ – and who is most at risk?

Long Covid: Respiratory and psychophysical sequelae among patients with COVID-19 four months after hospital discharge

Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline

Patients, clinicians seek answers to the mystery of ‘Long COVID’

Long Covid: 6-month consequences of COVID-19 in patients discharged from hospital

[Preprint] Characterizing Long COVID in an International Cohort: 7 Months of Symptoms and Their Impact

NICE Guideline: Managing the long-term effects of COVID-19

 

Comentário no Twitter

 

Novas ferramentas da OMS para a inclusão de pessoas com demência na sociedade.

11 Ago, 2021 | 10:39h

New WHO toolkit promotes inclusion of people with dementia in society – World Health Organization

Ver Diretriz: Towards a dementia inclusive society: WHO toolkit for dementia-friendly initiatives (DFIs) – World Health Organization

 

Comentário no Twitter (fio – clique para saber mais)

 

Encefalite autoimune mediada por anticorpos: uma abordagem prática.

9 Ago, 2021 | 11:08h

Antibody-mediated autoimmune encephalitis: A practical approach – Cleveland Clinic Journal of Medicine

Pesquisadores afirmam que médicos devem abandonar os exames de urina de rotina em pacientes idosos com delirium.

6 Ago, 2021 | 11:27h

Researchers tell doctors to avoid routine urinary tests for older patients with delirium – Johns Hopkins University School of Medicine

Artigo original: Things We Do for No Reason™: Obtaining Urine Testing in Older Adults With Delirium Without Signs or Symptoms of Urinary Tract Infection – Journal of Hospital Medicine ($)

 

Comentário no Twitter (fio – clique para saber mais)

 

Diretriz sobre diagnóstico e tratamento da polirradiculoneuropatia demielinizante inflamatória crônica.

5 Ago, 2021 | 11:43h

European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task Force—Second revision – European Journal of Neurology

Diretriz sobre Cannabis e analgesia com canabinoides – “Em razão da falta de evidências clínicas de alta qualidade, atualmente o IASP não endossa o uso generalizado de cannabis e canabinoides para alívio da dor.”

4 Ago, 2021 | 12:24h

International Association for the Study of Pain Presidential Task Force on Cannabis and Cannabinoid Analgesia position statement – Pain

Ver também:

Cannabinoids, cannabis, and cannabis-based medicine for pain management: a systematic review of randomised controlled trials – Pain

General risks of harm with cannabinoids, cannabis, and cannabis-based medicine possibly relevant to patients receiving these for pain management: an overview of systematic reviews – Pain

Comentários:

More evidence needed to back cannabis as pain treatment, says review – Imperial College London

Medicinal cannabis to manage chronic pain? We don’t have evidence it works – The Conversation

Conteúdos relacionados:

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Estudo randomizado | Tratamento de rotina com fluoxetina não reduz a incidência de depressão após AVC.

4 Ago, 2021 | 12:14h

Depression Outcomes Among Patients Treated With Fluoxetine for Stroke Recovery: The AFFINITY Randomized Clinical Trial – JAMA Neurology (free for a limited period)

Editorial: Poststroke Selective Serotonin Reuptake Inhibitors—Do They Work for Anything? (gratuito por tempo limitado)

Conteúdos relacionados:

[Abstract Only] Randomized trial: Fluoxetine does not improve functional recovery after acute stroke

Randomized Trial: Effects of Fluoxetine on Functional Outcomes After Acute Stroke

Estudo randomizado | Midodrina pode reduzir a recorrência de síncope vasovagal.

4 Ago, 2021 | 12:12h

Midodrine for the Prevention of Vasovagal Syncope: A Randomized Clinical Trial – Annals of Internal Medicine

Comentário: Midodrine Cuts Recurrent Syncope in Young, Healthy Patients – HealthDay

Resumo para pacientes: Summary for Patients: Midodrine to Prevent Fainting – Annals of Internal Medicine

 

Comentário no Twitter

 

Estudo randomizado | Pimavanserina na psicose relacionada à demência.

3 Ago, 2021 | 11:10h

Trial of Pimavanserin in Dementia-Related Psychosis – New England Journal of Medicine

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