Acesso livre
Acesso livre

Neurologia

Revisão sistemática | Anticoagulantes para AVC isquêmico agudo.

30 Nov, 2021 | 12:09h

Resumo: Early treatment with blood-thinning drugs for people who have had a stroke – Cochrane Library

Estudo original: Anticoagulants for acute ischaemic stroke – Cochrane Library

Benzodiazepínicos: usos, perigos e considerações clínicas.

30 Nov, 2021 | 12:08h

Benzodiazepines: Uses, Dangers, and Clinical Considerations – Neurology International

Ataque isquêmico transitório: avaliação e conduta no departamento de emergência.

30 Nov, 2021 | 12:05h

TIA: Emergency Department Evaluation and Disposition – emDocs

Conteúdos relacionados:

AHA/ASA Guideline: Prevention of stroke in patients with previous stroke and transient ischemic attack – prevention efforts should be based on the cause of the first ischemic event.

Stroke and transient ischaemic attack in over 16s: diagnosis and initial management – National Institute for Health and Care Excellence

Canadian Stroke Best Practice Recommendations for Acute Stroke Management

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

2 recent meta-analysis highlight the benefits of short term (30 days) dual antiplatelet therapy with aspirin + clopidogrel in patients within 24 hours of high-risk transient ischemic attack or mild-moderate ischemic stroke.

Prospective validation of Canadian TIA Score for subsequent stroke risk after transient ischemic attack

Systematic review: Multiple vs. fewer antiplatelet agents for preventing early recurrence after ischemic stroke or transient ischemic attack

Fadiga como queixa principal: epidemiologia, causas, diagnóstico e tratamento.

29 Nov, 2021 | 10:44h

Fatigue as the Chief Complaint: Epidemiology, Causes, Diagnosis, and Treatment – Deutsches Ärzteblatt International

Conteúdo relacionado: NICE Guideline | Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management.

Revisão sistemática | Quantificação do impacto anticolinérgico e sedativo em idosos com polifarmácia.

26 Nov, 2021 | 11:52h

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

 

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Epidemiologia global do AVC e acesso a intervenções para AVC isquêmico agudo.

25 Nov, 2021 | 15:04h

Global Epidemiology of Stroke and Access to Acute Ischemic Stroke Interventions – Neurology

Conteúdo relacionado: Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

Três sociedades neurológicas, incluindo a AAN, emitem forte diretriz de posicionamento sobre o aducanumabe.

24 Nov, 2021 | 11:25h

Three Neurologic Societies, Including the AAN, Issue Strong Position Statement on Aducanumab – Neurology Today

Ver diretriz: Decisions With Patients and Families Regarding Aducanumab in Alzheimer Disease, With Recommendations for Consent: AAN Position Statement – Neurology

Conteúdos relacionados:

Editorial: Aducanumab for Alzheimer’s disease?

FDA approvement of Alzheimer’s drug sparks controversy among doctors.

 

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Análise de segurança de estudos randomizados mostrou que o aducanumabe (medicamento para Alzheimer) causou edema cerebral em 35% dos pacientes e sintomas associados (cefaleia, confusão, tontura e náusea) em 26%.

24 Nov, 2021 | 11:24h

Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer Disease – JAMA Neurology

Comentário: Biogen Alzheimer’s drug shows brain swelling in 35% of patients – MedicalXpress

 

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Revisão sistemática | Inibidores seletivos de recaptação da serotonina (ISRS) na recuperação pós-AVC.

24 Nov, 2021 | 11:07h

Resumo: Selective serotonin reuptake inhibitors for stroke recovery – Cochrane Library

Artigo original: Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery – Cochrane Library

Conteúdos relacionados:

RCT: Routine treatment with fluoxetine does not reduce the incidence of depression after stroke.

[Abstract Only] Randomized trial: Fluoxetine does not improve functional recovery after acute stroke

Randomized Trial: Effects of Fluoxetine on Functional Outcomes After Acute Stroke

 

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M-A | Evidências atuais não suportam a redução intensiva da pressão arterial como estratégia preventiva de declínio cognitivo e demência.

23 Nov, 2021 | 15:38h

Evaluation of Intensive vs Standard Blood Pressure Reduction and Association With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis – JAMA Network Open

 

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