Neurologia
Cefaleia pós-craniotomia: etiologias e tratamentos.
3 Mar, 2022 | 15:23hPostcraniotomy Headache: Etiologies and Treatments – Current Pain and Headache Reports
Estudo randomizado | Melatonina profilática não reduz a incidência de delirium em pacientes em UTI.
1 Mar, 2022 | 15:27hProphylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial – Intensive Care Medicine (link para o resumo – $ para o texto completo)
Comentários no Twitter
Enteral prophylactic melatonin initiated early (within 48h of admission) & continued throughout #ICU (MAX 14 consecutive days) do not ⬇️#delirium prevalence vs placebo, Pro-MEDIC multicentre RCT
➡️12🇦🇺ICUs
➡️841 pts
➡️delirium-free assessments 79.2% vs 80%https://t.co/Gt5o1VuRo7 pic.twitter.com/gPRWxxmhHS— Intensive Care Medicine (@yourICM) February 28, 2022
In 841 ICU patients with expected stay >72h, 4 mg melatonin within 48h after admission for 14 days vs placebo made no sign. differences in delirium-free assessments, LoS, 90d mortality, nor quality & quantity of sleep
Good bye Melatonin, we had a good timehttps://t.co/d0dayil99W— Peter Nydahl (@NydahlPeter) February 28, 2022
Revisão | Nova geração de tratamentos psicológicos na dor crônica.
1 Mar, 2022 | 15:25hNew generation psychological treatments in chronic pain – The BMJ (gratuito por tempo limitado)
Estudo randomizado | Uma intervenção orientada por atenção plena (mindfulness) pode reduzir a dor crônica e o uso indevido de opioides na atenção primária.
1 Mar, 2022 | 15:10hMindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care: A Randomized Clinical Trial – JAMA Internal Medicine (link para o resumo – $ para o texto completo)
Comentário: Mindfulness-Based Intervention Found to Reduce Chronic Pain and Opioid Misuse – Psychiatric News Alert
Comentário no Twitter
A randomized clinical trial showed that #Mindfulness-Oriented Recovery Enhancement delivered in the primary care setting reduces opioid misuse by as much as 46%, while simultaneously reducing chronic pain and emotional distress. https://t.co/eNj42RBCRA @DrEricGarland pic.twitter.com/tBatMT9lkQ
— JAMA Internal Medicine (@JAMAInternalMed) February 28, 2022
Metanálise sugere que há baixo risco de hemorragia intracraniana tardia (depois de uma tomografia computadorizada negativa de cabeça) após traumatismo craniano contuso de baixa energia durante o uso de anticoagulantes orais diretos.
28 Fev, 2022 | 13:31hEstudo randomizado | Em sobreviventes comatosos de parada cardíaca, uma estratégia de supressão da atividade eletroencefalográfica (EEG) rítmica e periódica com uso de medicação anticonvulsivante não melhorou os desfechos neurológicos.
24 Fev, 2022 | 15:54hTreating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentário no Twitter
In trial of comatose patients after cardiac arrest, intensive antiseizure treatment adapted from protocols for status epilepticus did not result in fewer poor outcomes at 3 mos than standard treatment. https://t.co/dpH5cgwhvW pic.twitter.com/zVBHBYMRK9
— NEJM (@NEJM) February 23, 2022
Estudo randomizado | Dexmedetomidina sublingual reduz a agitação leve a moderada em pacientes com transtorno bipolar.
24 Fev, 2022 | 13:46hEffect of Sublingual Dexmedetomidine vs Placebo on Acute Agitation Associated With Bipolar Disorder: A Randomized Clinical Trial – JAMA (gratuito por tempo limitado)
Editorial: Sublingual Dexmedetomidine as a Potential New Treatment for Agitation – JAMA (gratuito por tempo limitado)
Comentário no Twitter
Randomized clinical trial found sublingual #dexmedetomidine at a dose of 180 μg or 120 μg reduced mild to moderate agitation in patients with #bipolar disorder. https://t.co/1VK2e15F7s pic.twitter.com/0oHw6eVMIP
— JAMA (@JAMA_current) February 22, 2022
M-A | Antidepressivos combinados vs. antidepressivos em monoterapia no tratamento de pacientes com depressão aguda.
22 Fev, 2022 | 15:27hCombining Antidepressants vs Antidepressant Monotherapy for Treatment of Patients With Acute Depression: A Systematic Review and Meta-analysis – JAMA Psychiatry (gratuito por tempo limitado)
M-A de estudos randomizados | Associação entre intensidade da redução do LDL-colesterol com terapias baseadas em estatinas e prevenção secundária de AVC.
22 Fev, 2022 | 15:24hEditorial: Low-Density Lipoprotein Cholesterol Level After a Stroke—Reducing It by Any Means (gratuito por tempo limitado)
Síncope de início precoce e tardio: compreensão do mecanismo.
22 Fev, 2022 | 15:19hEarly and late-onset syncope: insight into mechanisms – European Heart Journal
Comentário no Twitter
Early and late-onset syncope: insight into mechanisms https://t.co/OlAT50jIt8 @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/F2gzBH9X2i
— European Society of Cardiology Journals (@ESC_Journals) February 17, 2022