Neurologia

Diretrizes para o tratamento da doença de Parkinson.

29 Mar, 2022 | 14:06h

Guidelines for Parkinson’s disease treatment: consensus from the Movement Disorders Scientific Department of the Brazilian Academy of Neurology – Arquivos de Neuro-Psiquiatria

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Comentário de estudo | Sintomas podem estar presentes até 10 anos antes do diagnóstico da doença de Parkinson no ambiente de atenção primária.

29 Mar, 2022 | 13:51h

Symptoms Can Appear Up to 10 Years Before a Parkinson’s Disease Diagnosis in a Primary Care Setting – Neurology Today

Estudo original: Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population – JAMA Neurology (link para o resumo – $ para o texto completo)

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Estudo randomizado | Em pacientes com enxaqueca crônica e uso excessivo de medicações sintomáticas, a terapia de prevenção de enxaqueca sem trocar ou limitar a frequência da medicação usada em excesso foi não inferior à substituição por um sintomático diferente com a limitação máxima de 2 dias de tratamento/semana.

25 Mar, 2022 | 15:41h

Patient-Centered Treatment of Chronic Migraine With Medication Overuse: A Prospective, Randomized, Pragmatic Clinical Trial – Neurology (link para o resumo – $ para o texto completo)

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Associações de consumo de álcool e tabagismo com risco de doença e degeneração em indivíduos com esclerose múltipla.

25 Mar, 2022 | 15:26h

Associations of Alcohol Consumption and Smoking With Disease Risk and Neurodegeneration in Individuals With Multiple Sclerosis in the United Kingdom – JAMA Network Open

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Estudo de coorte | Risco de problemas de saúde mental em crianças e jovens após concussão.

25 Mar, 2022 | 15:25h

Risk of Mental Health Problems in Children and Youths Following Concussion – JAMA Network Open

Comentários:

Contextual Considerations for the Increased Risk of Mental Health Problems Following Concussion in Youth – JAMA Network Open

Concussion Linked to Mental Health Issues Among Children Aged 5 to 18 Years – HealthDay

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Estudo randomizado | Tratamento com dose única de anfotericina B lipossomal para meningite por criptococo.

25 Mar, 2022 | 15:01h

Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis – New England Journal of Medicine (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

Cryptococcal meningitis is a major complication of HIV infection. Single-dose liposomal amphotericin B combined with flucytosine and fluconazole was noninferior to the WHO-recommended treatment and was associated with fewer adverse events. https://t.co/cg9DqSDhyN pic.twitter.com/SrKx4tDaph

— NEJM (@NEJM) March 23, 2022

 

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Delirium está associado a aumento de mortes hospitalares.

25 Mar, 2022 | 14:34h

Comunicado de imprensa: Delirium linked to increase in hospital deaths – University of Edinburgh

Estudo original: Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency admissions – Age and Ageing

 

Comentário no Twitter

Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency admissions.
Thank you @emmavardy2 @A_MacLullich @atula_tweets Michael Cheng, Temi Ibitoye https://t.co/bBjBQ3xpTd

— Age_and_Ageing (@Age_and_Ageing) March 16, 2022

 

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Revisão | Síndrome das pernas inquietas.

24 Mar, 2022 | 12:06h

Restless legs syndrome – Nature Reviews Disease Primers (se o acesso a este link for pago, tente este)

Infográfico: Restless legs syndrome (se o acesso a este link for pago, tente este)

Conteúdo relacionado: The Management of Restless Legs Syndrome: An Updated Algorithm

 

Comentário no Twitter

#RestlessLegs syndrome is a sleep-related disorder characterized by an urge to move the legs, often accompanied by #insomnia and involuntary periodic leg movements during resting wakefulness or sleep.#WorldSleepDay https://t.co/qkpZhWIZke pic.twitter.com/yDO3P87KbL

— Nature Reviews Disease Primers (@DiseasePrimers) March 19, 2022

 

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Diretriz ANN | Aconselhamento prático para a prevenção de AVC na aterosclerose intracraniana arterial sintomática.

23 Mar, 2022 | 12:08h

Stroke Prevention in Symptomatic Large Artery Intracranial Atherosclerosis Practice Advisory: Report of the AAN Guideline Subcommittee – Neurology

Comunicado de imprensa: AAN issues guidance on preventing second stroke in those with plaque in brain arteries – American Academy of Neurology

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Avaliação de biomarcadores sanguíneos gliais e neuronais comparada às regras de decisão clínica na avaliação da necessidade de tomografia computadorizada em pacientes com lesão cerebral traumática leve.

23 Mar, 2022 | 11:46h

Evaluation of Glial and Neuronal Blood Biomarkers Compared With Clinical Decision Rules in Assessing the Need for Computed Tomography in Patients With Mild Traumatic Brain Injury – JAMA Network Open

 

Comentário no Twitter

In this prospective cohort of mTBI/concussion patients, CCHR, NOC and blood test GFAP/UCH-L1 were equally sensitive in detecting traumatic intracranial lesions on CT but CCHR had the highest specificity; GFAP combined with CCHR detected lesions best. https://t.co/hYwxg76uu8

— JAMA Network Open (@JAMANetworkOpen) March 14, 2022

 

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