Acesso livre
Acesso livre

Neurologia Pediátrica

Estudo de coorte | Associação do tratamento com antipsicóticos, antidepressivos ou ambos com transtornos do movimento e convulsões entre crianças e adolescentes com depressão.

21 Abr, 2022 | 11:26h

Association of Treatment With Antipsychotics, Antidepressants, or Both With Movement Disorders and Seizures Among Children and Adolescents With Depression in Korea – JAMA Network Open

 

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Estudo randomizado | Segurança e eficácia da ganaxolona em pacientes com distúrbio da deficiência de CDKL5.

20 Abr, 2022 | 14:53h

Safety and efficacy of ganaxolone in patients with CDKL5 deficiency disorder: results from the double-blind phase of a randomised, placebo-controlled, phase 3 trial – The Lancet Neurology (link para o resumo – $ para o texto completo)

Estudo randomizado | Efeito de diferentes esquemas de doses de corticosteroides sobre os desfechos clínicos em meninos com distrofia muscular de Duchenne.

8 Abr, 2022 | 21:46h

Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial – JAMA (gratuito por tempo limitado)

Conteúdos relacionados:

RCT: Routine lung volume recruitment is not beneficial for boys with Duchenne muscular dystrophy.

Phase 2 RCT: Repeated intravenous cardiosphere-derived cell therapy in late-stage Duchenne muscular dystrophy.

Research: Long-term effects of glucocorticoids in patients with Duchenne muscular dystrophy

 

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Estudo nacional de coorte de nascimento | Associação entre a exposição a medicamentos antipsicóticos na gestação e o risco de distúrbios do neurodesenvolvimento.

29 Mar, 2022 | 14:52h

Association of Antipsychotic Drug Exposure in Pregnancy With Risk of Neurodevelopmental Disorders: A National Birth Cohort Study – JAMA Internal Medicine (gratuito por tempo limitado)

Comentário: Antipsychotic Use During Pregnancy Generally Not Associated With Neurodevelopmental Risks – Psychiatric News Alert

Diretrizes clínicas europeias para a síndrome de Tourette e outros transtornos de tiques.

29 Mar, 2022 | 14:36h

Summary statement

Parte I: assessment

Parte II: psychological interventions

Parte III: pharmacological treatment

Parte IV: deep brain stimulation

Conteúdo relacionado: Guideline: Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders

Estudo de coorte | Risco de problemas de saúde mental em crianças e jovens após concussão.

25 Mar, 2022 | 15:25h

Risk of Mental Health Problems in Children and Youths Following Concussion – JAMA Network Open

Comentários:

Contextual Considerations for the Increased Risk of Mental Health Problems Following Concussion in Youth – JAMA Network Open

Concussion Linked to Mental Health Issues Among Children Aged 5 to 18 Years – HealthDay

Diretrizes sobre doença falciforme | Prevenção secundária de AVC em crianças e adolescentes.

23 Mar, 2022 | 11:47h

Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular guidelines project: Associação Médica Brasileira – 2022 – Hematology, Transfusion and Cell Therapy

Conteúdo relacionado: RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.

Estudo observacional | Comparação das medidas de pressão intracraniana antes e depois do tratamento com salina hipertônica vs. manitol em crianças com lesão cerebral traumática grave.

14 Mar, 2022 | 13:35h

Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury – JAMA Network Open

Comentário convidado: ADAPTing to a New Era of Comparative Effectiveness Research in Traumatic Brain Injury—Generating Evidence From Observational Data – JAMA Network Open

 

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Associação de insuficiência respiratória na primeira infância com desfechos neurocognitivos de longo prazo.

9 Mar, 2022 | 13:33h

Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes – JAMA (link para o resumo – $ para o texto completo)

Comentários:

IQ Lower for Survivors of PICU Respiratory Failure Hospitalization – HealthDay

Investigating The Effects of Critical Illness in Early Childhood On Neurocognitive Outcomes – University of Pennsylvania School of Nursing

Estudo de coorte | Associação entre tempo de exposição a telas em crianças de 1 ano de idade e transtorno do espectro autista aos 3 anos de idade.

8 Mar, 2022 | 16:09h

Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of Age: The Japan Environment and Children’s Study – JAMA Pediatrics

Comentário: Screen Time Linked to Autism Spectrum Disorder in Boys – HealthDay

Conteúdos relacionados:

M-A: Global prevalence of meeting screen time guidelines among children 5 years and younger.

Media and Young Minds – American Academy of Pediatrics

Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents – “children below 2 years age should not be exposed to any type of screen, whereas exposure should be limited to a maximum of one hour of supervised screen time per day for children 24-59 months age, and less than two hours per day for children 5-10 years age”.

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