Medicina de Família

O que os cientistas sabem sobre as novas e mais transmissíveis variantes do coronavírus.

26 Mai, 2021 | 10:42h

What scientists know about new, fast-spreading coronavirus variants – Nature

[Preprint] Metanálise de estudo randomizado: Ivermectina para tratamento de COVID-19 – não há melhora nos desfechos de mortalidade por qualquer causa, duração da internação ou clearance viral.

26 Mai, 2021 | 10:37h

Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – medRxiv

Comentário no Twitter

🆕💥💥Preprint
Ivermectin for the treatment of #COVID19 : A systematic review & meta-analysis of RCTs
10 RCTs
1173 patients
8 RCTs➡️ Mild
1 RCT ➡️ Moderate
1 RCT➡️ Mild& mod
Ivermectin did not reduce all-cause mortality,length of stay or viral clearance https://t.co/QMx0wlfS8f pic.twitter.com/6yddqwqPF6

— Antibiotic Steward 🇵🇸💔Bassam Ghanem (@ABsteward) May 25, 2021

Estudo mostra distúrbios no controle glicometabólico agudo e de longo prazo após infecção por SARS-CoV-2.

26 Mai, 2021 | 10:34h

Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection – Nature Metabolism

Relacionado: Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? – The Lancet Diabetes & Endocrinology E SARS-CoV-2 infects human pancreatic β-cells and elicits β-cell impairment – Cell Metabolism

Comentário no Twitter

For at least 2 months after COVID-19 in people without #diabetes, glucose regulation can be abnormal, along with insulin resistance and abnormal cytokineshttps://t.co/P1xa0lx2c4 @NatMetabolism @PAOLOFIORINA @FiorinaLab pic.twitter.com/Lu7GDMjzdy

— Eric Topol (@EricTopol) May 25, 2021

O status respiratório na admissão prediz a mortalidade na COVID-19 – Pacientes hipoxêmicos (saturação de oxigênio abaixo de 92%) tiveram de 1,8 a 4 vezes mais risco de mortalidade; aqueles com frequência respiratória acima de 22 respirações por minuto tiveram risco de mortalidade aumentado em 1,9 a 3,2 vezes.

25 Mai, 2021 | 15:53h

Admission respiratory status predicts mortality in COVID-19 – Influenza and Other Respiratory Virus

Comentários: COVID-19 mortality associated with 2 signs easily measured at home – University of Washington School of Medicine E Low oxygen levels, shallow breathing tied to COVID death – CIDRAP

2 signs easily measured at home can indicate increased Covid mortality risk—respiration rate & blood-oxygen saturation. Both are distinctly predictive of higher mortality. Anyone receiving a positive Covid test can easily monitor for these signs at home https://t.co/8n7oc0d4E4 pic.twitter.com/02ysVaElsL

— delthia ricks 🔬 (@DelthiaRicks) May 24, 2021

Revisão sistemática: As evidências são insuficientes para determinar os riscos e os benefícios da suplementação de vitamina D como tratamento da COVID-19.

25 Mai, 2021 | 15:52h

Vitamin D supplementation for the treatment of COVID‐19: a living systematic review – Cochrane Library

Resumo: Is vitamin D an effective and safe treatment for COVID-19? – Cochrane Library

Estudo mostra que COVID-19 leve induz proteção duradoura por anticorpos.

25 Mai, 2021 | 15:50h

Mild COVID-19 induces lasting antibody protection, study finds – Washington University School of Medicine

Estudo original: SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans – Nature

Comentário no Twitter (fio – clique para saber mais)

Just published @nature
After even mild covid infections there are, in addition to memory B cells, bone marrow plasma cells are induced to provide long-term protection > 1 yrhttps://t.co/zVfUFvciVk @TheBcellArtist @WUSTLmed
(NB vaccination still provides further protection) pic.twitter.com/rUd8pMAP1T

— Eric Topol (@EricTopol) May 24, 2021

Perspectiva | Coronavírus: muitas variantes, mas as vacinas continuam eficazes.

25 Mai, 2021 | 15:48h

C oronavirus: so many variants, but vaccines are still effective – The Conversation

Relatório Clínico AAP: Cuidado colaborativo na identificação e no tratamento da psicose em adolescentes e adultos jovens.

25 Mai, 2021 | 15:46h

Collaborative Care in the Identification and Management of Psychosis in Adolescents and Young Adults – Pediatrics

Metanálise: Nova geração de antidepressivos para crianças e adolescentes – “a maioria dos novos antidepressivos pode reduzir os sintomas da depressão de forma modesta e com relevância clínica incerta, em comparação com placebo.”

25 Mai, 2021 | 15:46h

New generation antidepressants for depression in children and adolescents: a network meta‐analysis – Cochrane Library

Resumo: Newer generation antidepressants for depression in children and adolescents: a network meta-analysis – Cochrane Library

Comentário: Best evidence suggests antidepressants aren’t very effective in kids and teens. What can be done instead? – The Conversation

OMS: O impacto da COVID-19 nas metas globais de saúde – A doença foi responsável por, pelo menos, 3 milhões de mortes a mais em 2020.

24 Mai, 2021 | 11:09h

The impact of COVID-19 on global health goals – World Health Organization

Relacionado: Covid-19 pandemic: approximately one million excess deaths occurred in 2020 in 29 high income countries. E Perspective | Tracking lives we’ve lost to COVID-19. E COVID-19 has caused 6.9 million deaths globally, more than double what official reports show