Medicina de Emergências
Estudo randomizado | Nem remdesivir nem hidroxicloroquina afetam o clearance viral em pacientes hospitalizados com COVID-19.
14 Jul, 2021 | 11:48hComunicado de imprensa: Neither remdesivir nor HCQ affect viral clearance in hospitalized patients with COVID-19 – American College of Physicians
Estudo original: Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 – Annals of Internal Medicine
Comentário no Twitter
Newly published research in Annals concludes neither remdesivir nor #hydroxychloroquine affected viral clearance in hospitalized patients with #COVID19 https://t.co/K3qWLUW8uY. pic.twitter.com/ugbjJJ3qI5
— Annals of Int Med (@AnnalsofIM) July 12, 2021
Alerta de segurança do FDA | Coloides sintéticos a base de amido hidroxietil não devem ser usados, a menos que não exista tratamento alternativo disponível.
14 Jul, 2021 | 11:20hComentário: FDA Piles on New Warnings for Blood Volume Expanders – MedPage Today (necessário cadastro gratuito)
Relacionados: Hydroxyethyl-starch Solutions (HES) Should no Longer be Used – European Medicines Agency E Randomized Trial: Hydroxyethyl Starch vs. Saline for Volume Replacement Therapy in High-Risk Patients Undergoing Major Abdominal Surgery E Systematic Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People
Diretriz nacional alemã para tratamento de pacientes hospitalizados com COVID-19.
13 Jul, 2021 | 11:30hCasos extremamente raros de Guillain-Barré relatados com a vacina da Johnson & Johnson contra a Covid-19.
13 Jul, 2021 | 11:24hJ&J’s Covid-19 vaccine may trigger neurological condition in rare cases, FDA says – STAT
Ver também: Johnson & Johnson Vaccine Is Linked To Neurological Disorder In Extremely Rare Cases – NPR E F.D.A. Attaches Warning of Rare Nerve Syndrome to Johnson & Johnson Vaccine – The New York Times
Podcast | Uso de antibióticos.
13 Jul, 2021 | 11:16h#284 An Antibiotics Primer, with @IDdocAdi – The Curbsiders
Outro estudo randomizado avaliou a eficácia e a qualidade de vida no tratamento somente com antibióticos da apendicite aguda não complicada.
13 Jul, 2021 | 11:16hA Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial – Annals of Surgery (link para o resumo – $ para o texto completo)
Relacionado: A Randomized trial comparing antibiotics with appendectomy for appendicitis E Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin E Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis E Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis E Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children E Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International
Comentário no Twitter
The debate continues!
Another RCT comparing antibiotics to surgery for uncomplicated appendicitis – COMMA trial from 🇮🇪
Recurrence within 1-year : 25% after AB
Superior quality of life at 3 and 12mo after surgery.https://t.co/Yv51qpxchb
— Ville Sallinen (@villesallinen) July 11, 2021
Revisão | Encefalopatias associadas a doenças infecciosas.
13 Jul, 2021 | 11:13hInfectious disease-associated encephalopathies – Critical Care
Comentário no Twitter
A Review published in Critical Care focuses on the pathophysiology of encephalopathies associated with sepsis, malaria, influenza, and COVID-19; emerging therapeutic strategies; and the role of neuroinflammation. https://t.co/991S4kAKJk
— BMC (@BioMedCentral) July 11, 2021
10 tópicos principais para reconhecimento, avaliação e tratamento da sepse materna.
13 Jul, 2021 | 11:12hEstudo randomizado | Comparação da cetamina nebulizada em 3 regimes de dose diferentes para o tratamento de condições dolorosas no departamento de emergência.
13 Jul, 2021 | 11:11hComparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the Emergency Department: A Prospective, Randomized, Double-Blind Clinical Trial – Annals of Emergency Medicine (link para o resumo – $ para o texto completo)
Comentário no Twitter
Nebulized Ketamine for pain in the ED? No way…Well- here you go-Comparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the ED. https://t.co/v3UT0Y0LdU #FOAMed #FOAMems #FOAMtox #FOAMcc #FOAMpharm
— Sergey Motov (@painfreeED) July 3, 2021
M-A | Mortalidade similar tanto com fluoroquinolonas quanto com macrolídeos no tratamento da pneumonia por Legionella.
13 Jul, 2021 | 11:08hAre Fluoroquinolones or Macrolides Better for Treating Legionella Pneumonia? A Systematic Review and Meta-analysis – Clinical Infectious Diseases (link para o resumo – $ para o texto completo)