Acesso livre
Acesso livre

Medicina de Emergências

Editorial | Uso excessivo de antibióticos: gerenciamento da incerteza e mitigação contra o tratamento em excesso.

26 Jul, 2021 | 09:58h

Antibiotic overuse: managing uncertainty and mitigating against overtreatment – BMJ Quality & Safety

 

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Opinião | Tocilizumabe no tratamento da COVID-19: quem se beneficia e como? – Os pesquisadores sugerem que inibidores de IL-6 talvez devam ser ministrados somente a pacientes com altos níveis de IL-6.

23 Jul, 2021 | 10:18h

Tocilizumab in COVID-19 therapy: who benefits, and how? – The Lancet

Relacionado: A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19. E M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction in mortality from 25% to 21% with IL-6 inhibition added to glucocorticoids may not translate to patients with a lower baseline mortality risk and likely do not justify the additional expense and risk for toxicities for patients hospitalized with modest oxygen requirements and a stable clinical course (from editorial)”. E RECOVERY trial: In hospitalized COVID-19 patients with hypoxia and systemic inflammation (C-reactive protein ≥75 mg/L), tocilizumab improved survival and other clinical outcomes E Secondary analysis of RCT finds Tocilizumab was beneficial to patients hospitalized with Covid-19 if CRP levels were greater than 15.0 mg/dL, but not if CRP levels were 15.0 mg/dL or less. E M-A: Tocilizumab in COVID-19 – “For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required”.

Revisão | Ética no uso do suporte respiratório extracorpóreo.

23 Jul, 2021 | 10:05h

Ethics in extracorporeal life support: a narrative review – Critical Care

Uma revisão narrativa sobre o papel da bacteriúria por Staphylococcus aureus na bacteriemia por S. aureus.

22 Jul, 2021 | 12:52h

A Narrative Review on the Role of Staphylococcus aureus Bacteriuria in S. aureus Bacteremia – Open Forum Infectious Diseases

 

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Estudo randomizado | Realimentação oral imediata em pacientes com pancreatite aguda leve e moderada.

22 Jul, 2021 | 12:50h

Immediate Oral Refeeding in Patients With Mild and Moderate Acute Pancreatitis: A Multicenter, Randomized Controlled Trial (PADI trial) – Annals of Surgery (link para o resumo – $ para o texto completo)

Estudo de coorte | Anemia falciforme e desfechos de COVID-19 – “Nossa análise estima um aumento de 4 vezes no risco de hospitalização por COVID-19 e de 2,6 vezes no risco de morte relacionada a COVID-19 em pacientes com anemia falciforme.”

21 Jul, 2021 | 09:55h

Sickle Cell Disorders and Severe COVID-19 Outcomes: A Cohort Study – Annals of Internal Medicine

Eclâmpsia ou pré-eclâmpsia pós-parto: definição e tratamento dos distúrbios hipertensivos da gravidez.

21 Jul, 2021 | 09:52h

Postpartum preeclampsia or eclampsia: defining its place and management among the hypertensive disorders of pregnancy – American Journal of Obstetrics & Gynecology

 

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Diretriz da OMS para manejo clínico da síndrome de trombose com trombocitopenia após vacinação contra coronavírus (COVID-19).

20 Jul, 2021 | 10:58h

Guidance for clinical case management of thrombosis with thrombocytopenia syndrome (TTS) following vaccination to prevent coronavirus disease (COVID-19) – World Health Organization

Diretriz relacionada: AHA/ASA Guidance: Diagnosis and Management of Cerebral Venous Sinus Thrombosis with Vaccine-Induced Thrombotic Thrombocytopenia – “No heparin products in any dose should be given.” E ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia

OMS alerta que a infecção por HIV aumenta o risco de COVID-19 grave e crítica.

20 Jul, 2021 | 10:56h

Comunicado de imprensa: WHO warns that HIV infection increases risk of severe and critical COVID-19 – World Health Organization

Relatório: WHO report on clinical features and prognostic factors of COVID-19 in people living with HIV hospitalized with SARS-CoV-2 infection

Relacionado: M-A: Epidemiology and outcomes of COVID-19 in HIV-infected individuals – HIV is a significant risk factor for acquiring SARS-CoV-2 infection and is associated with a higher risk of mortality.

 

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Registro Internacional | AVC isquêmico e hemorrágico entre pacientes criticamente doentes com Covid-19.

20 Jul, 2021 | 10:55h

Ischemic and Hemorrhagic Stroke Among Critically Ill Patients With Coronavirus Disease 2019: An International Multicenter Coronavirus Disease 2019 Critical Care Consortium Study – Critical Care Medicine

Relacionado: SARS-CoV-2 and Stroke Characteristics – higher rate of large vessel occlusions and stroke in young patients E Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19 E Case-control study: COVID-19-associated stroke is associated with worse outcomes and increased mortality E Pictorial essay: Neurological emergencies associated with COVID-19: stroke and beyond E Characteristics and Outcomes in Patients With COVID-19 and Acute Ischemic Stroke E Risk of Ischemic Stroke in Patients with COVID-19 vs. Patients with Influenza

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