Medicina de Emergências
Estudo de coorte | Marcadores sorológicos de lesão cerebral podem predizer bom desfecho neurológico após parada cardíaca fora do ambiente hospitalar.
7 Set, 2021 | 22:01h
Comentário no Twitter
Established/novel blood brain injury markers early predict good neuro-outcome/absence of pathological prognostic findings post CA
🧠NSE/S100B may prevent premature WLST
🧠NFL highest predictive capacity
Here visual abstract, full results #FOAMcc @yourICM https://t.co/3klcew33bD pic.twitter.com/1agsFCw6RF— Intens Care Med (@yourICM) September 4, 2021
Podcast | Testes hepáticos.
7 Set, 2021 | 21:52h#293 The Best of Liver Tests with Dr. Elliot Tapper – The Curbsiders
Estudo randomizado | Tratamento precoce da COVID-19 com anakinra orientado pelos níveis plasmáticos de receptor de plasminogênio de uroquinase solúvel.
6 Set, 2021 | 16:34h
Comentário no Twitter
The SAVE-MORE phase 3 study demonstrates the efficacy of anakinra, an IL-1α/β inhibitor, in patients with COVID-19 and high serum levels of soluble plasminogen activator receptor, according to a @NatureMedicine paper. https://t.co/aM5teLMipK pic.twitter.com/bTVNqbBOcv
— Nature Portfolio (@NaturePortfolio) September 3, 2021
Estudo mostra que as concentrações de troponina cardíaca à apresentação são insuficientes para distinguir infarto do miocárdio tipo 1 de outras causas de lesão miocárdica.
6 Set, 2021 | 16:21h
Comentário no Twitter
Cardiac troponin release kinetics: levels at presentation cannot distinguish type 1 MI from other causes of injury or infarction. Results now online @CircAHA https://t.co/8cjyl6SGai@HighSTEACS @chapdoc1 @djlmed @DorienKimenai @EdinUniCVS pic.twitter.com/v0RoD532Jx
— Ryan Wereski (@RyanWereski) June 25, 2021
Estudo de coorte diagnóstica | Diferenciação entre causas centrais e periféricas da vertigem aguda em ambiente de emergência com os testes HINTS, STANDING e ABCD2.
6 Set, 2021 | 16:13hDifferentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study – Academic Emergency Medicine (link para o resumo – $ para o texto completo)
Comentário: Can We Detect Central Vertigo on Exam? – Journal Feed
Estudo randomizado | Baricitinibe reduziu a mortalidade em adultos hospitalizados com COVID-19.
3 Set, 2021 | 11:22hComentários:
Comentários no Twitter
NEW—Baricitinib did not improve the composite primary endpoint of progression to NIV,
high-flow O2, IMV, or death; however, it did reduce 28-day all-cause mortality by 38·2% vs placebo (HR 0·57 [95% CI 0·41–0·78])Read the COV-BARRIER study: https://t.co/QrU6GW0XcQ#ISICEM2021
— The Lancet Respiratory Medicine (@LancetRespirMed) September 1, 2021
(thread – click for more)
1/🧵💥 NEW COVID THERAPY SAVES LIVES
Adding baricitinib to steroids will save 1,000s of hospitalized #COVID pts. Our @LancetRespirMed COV-Barrier study is FREE.
I explain👇why it’s such a great #Pandemic discovery story: a new way to ⬇️ COVID19 deaths.https://t.co/8I5BlwyT2R pic.twitter.com/6KcfQrljqC
— WesElyMD (@WesElyMD) September 1, 2021
Diretriz científica | Covid-19 e insuficiência cardíaca.
3 Set, 2021 | 11:19h
Comentário no Twitter
Released today: Coronavirus Disease-2019 and Heart Failure: A Scientific Statement from @HFSA, published in @JCardFail. @dranulala @ankeetbhatt @EricAdler17 @BhadeliaMD @AshishCorrea @ersied727 @heartofthemater @AndrewJSauer @NMHheartdoc @scottdsolomon https://t.co/fyWab32ruU pic.twitter.com/8pNY60I6gD
— HFSA (@HFSA) September 1, 2021
Estudo randomizado | Entre pacientes criticamente doentes, a meta de oxigenação em um intervalo normal baixo vs. intervalo normal alto não resultou em redução na disfunção de órgãos.
3 Set, 2021 | 11:12hEffect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA (gratuito por tempo limitado)
Conteúdos relacionados:
M-A of randomized trials: Conservative oxygen therapy for critically ill patients.
Oxygen administration for patients with ARDS – Journal of Intensive Care
Comentário no Twitter
Multicenter RCT found, among critically ill patients, targeting oxygenation to a low-normal range compared with a high-normal range did not result in a statistically significant reduction in organ dysfunction https://t.co/lEq28bqmM4 #ISICEM21
— JAMA (@JAMA_current) August 31, 2021
Estudo randomizado | Em pacientes com insuficiência respiratória hipoxêmica, uma estratégia de ventilação com volume corrente mais baixo, facilitada pela remoção extracorpórea de dióxido de carbono, não foi associada com desfechos melhores.
3 Set, 2021 | 11:10hEffect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial – JAMA (gratuito por tempo limitado)
Conteúdo relacionado: Randomized Trial: Low vs Intermediate Tidal Volume Strategy in ICU Patients Without ARDS
Comentário no Twitter
In this randomized clinical trial that included 412 adults, 90-day mortality was 41.5% in the extracorporeal carbon dioxide removal group and 39.5% in the standard care group, a difference that was not statistically significant https://t.co/jhCY2r4qjX #ISICEM21
— JAMA (@JAMA_current) August 31, 2021
Estudo randomizado | Administração de cetamina em pacientes em crise dolorosa aguda de doença falciforme foi efetiva no controle da dor e reduziu a dose cumulativa de morfina no departamento de emergência.
3 Set, 2021 | 10:58hKetamine Administration for Acute Painful Sickle Cell Crisis: A Randomized Controlled Trial – Academic Emergency Medicine (link para o resumo – $ para o texto completo)