Medicina de Emergências

Revisão | Manifestações cutâneas da lesão renal aguda.

4 Ago, 2022 | 14:00h

Cutaneous manifestations of acute kidney injury – Clinical Kidney Journal

 

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Revisão | Tratamento da lesão renal aguda em pacientes oncológicos.

4 Ago, 2022 | 13:59h

Treatment of acute kidney injury in cancer patients – Clinical Kidney Journal

Conteúdos relacionados:

Onconephrology: Update in Anticancer Drug-Related Nephrotoxicity – Nephron

Acute Kidney Injury in Critically Ill Patients with Cancer – Clinical Journal of the American Society of Nephrology

Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents – Kidney Research and Clinical Practice

KDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer – Kidney International

 

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M-A | Estratégia de suporte respiratório em adultos com insuficiência respiratória hipoxêmica aguda.

2 Ago, 2022 | 13:15h

Respiratory support strategy in adults with acute hypoxemic respiratory failure: a systematic review and network meta-analysis – JA Clinical Reports

 

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Estudo de coorte | Análise de prescrições para terapia antiplaquetária dupla após AVC isquêmico agudo.

1 Ago, 2022 | 15:09h

Analysis of Prescriptions for Dual Antiplatelet Therapy After Acute Ischemic Stroke – JAMA Network Open

Conteúdos relacionados:

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

Multiple versus fewer antiplatelet agents for preventing early recurrence after ischaemic stroke or transient ischaemic attack – Cochrane Library

2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association – Stroke

Stroke and transient ischaemic attack in over 16s: diagnosis and initial management – National Institute for Health and Care Excellence

Dual Antiplatelet Therapy Versus Aspirin in Patients With Stroke or Transient Ischemic Attack: Meta-Analysis of Randomized Controlled Trials – Stroke

Efficacy and Safety of Using Dual Versus Monotherapy Antiplatelet Agents in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials – Circulation

 

Comentário no Twitter

In this cohort study, dual antiplatelet of aspirin and clopidogrel was underused in patients with minor ischemic stroke and potentially overused in non-minor ischemic stroke, with substantial hospital variations. https://t.co/rZeGbMgF1E

— JAMA Network Open (@JAMANetworkOpen) July 28, 2022

 

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Estudo randomizado | Tixagevimabe-cilgavimabe para tratamento de pacientes internados com COVID-19.

18 Jul, 2022 | 13:36h

Tixagevimab–cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trial – The Lancet Respiratory Medicine

Comentário: The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients – News Medical

Conteúdos relacionados:

Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Respiratory Medicine

Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19 – New England Journal of Medicine

 

Comentário no Twitter

In pts hospitalised w/ COVID-19 receiving remdesivir and other standard care, tixagevimab–cilgavimab did not improve time to sustained recovery but was safe and mortality was lower vs placebo

From the ACTIV-3–TICO Study Group https://t.co/zaaXBQYl5t pic.twitter.com/xe0tmbFrZ9

— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022

 

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M-A (maioria de estudos observacionais) | Trombólise guiada por cateter vs. anticoagulação sistêmica isolada para embolia pulmonar submaciça.

18 Jul, 2022 | 13:20h

Meta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism – American Journal of Cardiology

 

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Estudo randomizado | Trombectomia endovascular isoladamente NÃO é não inferior à ponte trombolítica padrão associada a trombectomia endovascular dentro de 4,5 horas do início do AVC.

14 Jul, 2022 | 12:05h

Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)

Estudo relacionado: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf

— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022

 

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Estudo randomizado | Trombectomia isolada NÃO é não inferior a alteplase intravenosa com trombectomia em pacientes com AVC.

14 Jul, 2022 | 12:04h

Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)

Estudo relacionado: Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf

— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022

 

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Tratamento da febre em adultos: revisão sistemática com metanálise e análises de estudos sequenciais.

14 Jul, 2022 | 12:01h

Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses – The BMJ

 

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Navegando em um mundo complicado | Comentário sobra as novas diretrizes de dor torácica do AHA/ACC.

13 Jul, 2022 | 12:16h

Navigating a Complicated World: The American Heart Association/American College of Cardiology/American College of Chest Physicians/Society of Academic Emergency Medicine/Society of Cardiovascular Computed Tomography/Society of Cardiovascular Magnetic Resonance Chest Pain Guidelines – CHEST

Diretriz original: 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

Comunicado de imprensa: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released

Eixo da diretriz: Guideline for the Evaluation and Diagnosis of Chest Pain

Pontos principais: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology

Comentário: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD

 

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