Infectologia

Estudo randomizado | Em crianças com pneumonia adquirida na comunidade, antibioticoterapia ambulatorial por 5 dias resultou em taxas de resposta clínica similares às obtidas com a estratégia padrão de 10 dias.

20 Jan, 2022 | 22:04h

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics (gratuito por tempo limitado)

Comentários:

Trial finds 5 days of antibiotics superior to 10 for kids with pneumonia – CIDRAP

Shorter antibiotics treatment is better for young children with outpatient pneumonia – Vanderbilt University Medical Center

Conteúdos relacionados:

ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections

Treatment of urinary tract infections in infants <2 Months: A Living Systematic Review – short and long duration of parenteral antibiotics were associated with a similar risk of UTI recurrence.

RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.

Randomized Trial: Seven vs. Fourteen Days of Antibiotic Therapy for Uncomplicated Gram-negative Bacteremia

Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia

Estudo randomizado | Prolongar os regimes de antibióticos intravenosos profiláticos não é benéfico após reconstrução endoprotética para tumores ósseos de membro inferior.

20 Jan, 2022 | 22:02h

Comparison of Prophylactic Intravenous Antibiotic Regimens After Endoprosthetic Reconstruction for Lower Extremity Bone Tumors: A Randomized Clinical Trial – JAMA Oncology

Comentário: No Benefit Seen With Longer Antibiotic Course After Surgery for Bone Tumors – Cancer Therapy Advisor

Revisão sistemática | Antibióticos profiláticos intermitentes para bronquiectasia.

20 Jan, 2022 | 21:57h

Intermittent prophylactic antibiotics for bronchiectasis – Cochrane Library

Resumo: Long term antibiotics taken at regular intervals by people with bronchiectasis – Cochrane Library

Diretrizes de prática clínica para o monitoramento do tratamento medicamentoso com teicoplanina.

20 Jan, 2022 | 21:53h

Clinical practice guidelines for therapeutic drug monitoring of teicoplanin: a consensus review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring – Journal of Antimicrobial Chemotherapy

[Ainda não publicado] Estudo feito em Israel mostra que reforço com 4ª dose de vacina contra COVID tem eficácia limitada.

20 Jan, 2022 | 21:37h

Israel Finds Fourth COVID Booster is Ineffective, While Hospitalised Omicron Patients Fare Much Better Than Delta Patients – Health Policy Watch

Ver também:

Israeli trial, world’s first, finds 4th dose ‘not good enough’ against Omicron – The Times of Israel

Israel study: 4th vaccine shows limited results with omicron – MedicalXpress

COVAX entrega bilionésima dose de vacina contra COVID-19 – mas 41% do mundo continua não vacinado.

20 Jan, 2022 | 21:36h

COVAX Delivers One Billionth COVID-19 Vaccine Dose – But 41% of World Remains Unvaccinated – Health Policy Watch

Ver também: COVID program delivers 1 billion doses to poorer countries – Associated Press

Conteúdos relacionados:

Is Covax finally going to vaccinate the world?

How Covax failed on its promise to vaccinate the world – “Covax, described as “naively ambitious” by one expert, has contributed just 5% of all vaccines administered globally”.

Perspective | A beautiful idea: how COVAX has fallen short.

WHO Launches Strategy to Achieve Global Covid-19 Vaccination by mid-2022.

WHO special envoys: To beat Covid, there’s a simple lesson – no one’s safe until everyone’s safe.

Joint COVAX Statement on the Equal Recognition of Vaccines – COVAX urges all government authorities to recognize as fully vaccinated all people who have received COVID-19 vaccines that have been deemed safe and effective by WHO.

WHO COVAX Joint Statement: Call to action to equip COVAX to deliver 2 billion doses in 2021.

Covax: How will Covid vaccines be shared around the world?

Medidas implementadas no ambiente escolar para conter a pandemia de COVID-19: breve revisão.

20 Jan, 2022 | 21:34h

Measures implemented in the school setting to contain the COVID‐19 pandemic: a rapid review – Cochrane Library

Comunicado de imprensa: Measures implemented in the school setting to contain the COVID-19 pandemic: a rapid review – Cochrane Library

Evidências atualizadas da Cochrane sobre COVID-19.

20 Jan, 2022 | 21:33h

COVID-19 evidence: a Cochrane round-up – Cochrane Library

Estudo levanta dúvidas sobre a confiabilidade dos testes rápidos para Covid nos primeiros dias após a infecção.

20 Jan, 2022 | 21:31h

Study raises doubts about rapid Covid tests’ reliability in early days after infection – STAT

Artigo original (preprint): Discordant SARS-CoV-2 PCR and Rapid Antigen Test Results When Infectious: A December 2021 Occupational Case Series – medRxiv

É o momento de passar das máscaras cirúrgicas e de tecido para N95? Questões respondidas.

20 Jan, 2022 | 21:29h

Time to upgrade from cloth and surgical masks to respirators? Your questions answered – The Conversation

Ver também: The CDC updated its mask guidelines. What to know about ‘the highest level of protection’ – CNN

Conteúdo relacionado: CDC urges Americans to wear most-protective mask or respirator that fits well and that they’ll wear consistently.